Progressive Supranuclear Palsy |
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Progressive Supranuclear Palsy
 Signs and Symptoms
Diagnosis
Treatment
Signs and Symptoms The signs and symptoms of progressive supranuclear palsy (PSP) vary from patient to patient but loss of balance while walking is the most common first symptom. Patients may have unexplained falls or a stiffness and awkwardness when walking. Sometimes the falls are described as attacks of dizziness, which can lead to an incorrect diagnosis of an inner ear problem.
Other common early symptoms include a loss of interest in usual hobbies or recreational activities, increased irritability and forgetfulness. Patients may suddenly laugh or cry, be apathetic or have occasional angry outbursts for no apparent reason.
As the disease progresses, many patients develop blurring of vision and problems controlling eye movements. PSP patients have trouble voluntarily shifting their gaze downward and can have trouble controlling their eyelids. This can lead to involuntary closing of the eyes, prolonged or infrequent blinking, or difficulty in opening the eyes. Another common visual problem is an inability to maintain eye contact during a conversation. This can give the mistaken impression that the patient is hostile or uninterested.
In addition, with PSP speech usually becomes slurred. Swallowing solid foods or liquids can be difficult. In rare cases, some patients will experience shaky hands.
Reviewed by health care specialists at UCSF Medical Center.
Last updated May 8, 2007
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