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Aimee Kao, M.D.

Neurologist

Dr. Aimee Kao is an expert in the diagnosis and treatment of age-related cognitive conditions such as Alzheimer's disease, Lewy body desease (dementia with Lewy bodies) and frontotemporal lobar degeneration. Kao's research uses model organisms such as the roundworm, C. elegans, to understand the basic mechanisms of neurodegenerative diseases.

Kao received her B.S. degree from Brown University and her M.D. and Ph.D. degrees from the University of Iowa School of Medicine. She completed her internship at the Beth Israel-Deaconess Hospital and her neurology residency at UCSF, where she was chief resident. She has fellowship training in behavioral neurology and molecular genetics. Kao joined the UCSF faculty in 2007. She is an assistant professor of neurology.

Clinics

Memory and Aging Center
1500 Owens St., Suite 320
San Francisco, CA 94158
Phone: (415) 353-2057
Fax: (415) 476-4800

Hours: Monday to Friday
8 a.m. – 5 p.m.

Conditions & Treatments

More about Aimee Kao

Education

University of Iowa, College of Medicine 2000

Residencies

Beth Israel-Deaconness Hospital, Internal Medicine 2001
UCSF Medical Center, Neurology 2004

Selected Research and Publications

  1. Chuang CH, Lin SH, Chen CY, Sheu BS, Kao AW, Wang JD. Increasing Incidence and Lifetime Risk of Inflammatory Bowel Disease in Taiwan: A Nationwide Study in a Low-endemic Area 1998-2010. Inflamm Bowel Dis. 2013 Dec; 19(13):2815-9.
  2. Judy ME, Nakamura A, Huang A, Grant H, McCurdy H, Weiberth KF, Gao F, Coppola G, Kenyon C, Kao AW. A shift to organismal stress resistance in programmed cell death mutants. PLoS Genet. 2013; 9(9):e1003714.
  3. Boxer AL, Gold M, Huey E, Hu WT, Rosen H, Kramer J, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, Mackenzie IR, Mitic L, Roberson ED, Van Kammen D, Cantillon M, Zahs K, Jackson G, Salloway S, Morris J, Tong G, Feldman H, Fillit H, Dickinson S, Khachaturian ZS, Sutherland M, Abushakra S, Lewcock J, Farese R, Kenet RO, Laferla F, Perrin S, Whitaker S, Honig L, Mesulam MM, Boeve B, Grossman M, Miller BL, Cummings JL. The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: the next therapeutic frontier). Alzheimers Dement. 2013 Mar; 9(2):189-98.
  4. Boxer AL, Gold M, Huey E, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, Mackenzie IR, Mitic L, Roberson ED, Van Kammen D, Cantillon M, Zahs K, Salloway S, Morris J, Tong G, Feldman H, Fillit H, Dickinson S, Khachaturian Z, Sutherland M, Farese R, Miller BL, Cummings J. Frontotemporal degeneration, the next therapeutic frontier: molecules and animal models for frontotemporal degeneration drug development. Alzheimers Dement. 2013 Mar; 9(2):176-88.
  5. Kao AW, Eisenhut RJ, Martens LH, Nakamura A, Huang A, Bagley JA, Zhou P, de Luis A, Neukomm LJ, Cabello J, Farese RV, Kenyon C. A neurodegenerative disease mutation that accelerates the clearance of apoptotic cells. Proc Natl Acad Sci U S A. 2011 Mar 15; 108(11):4441-6.
  6. Kao AW, Racine CA, Quitania LC, Kramer JH, Christine CW, Miller BL. Cognitive and neuropsychiatric profile of the synucleinopathies: Parkinson disease, dementia with Lewy bodies, and multiple system atrophy. Alzheimer Dis Assoc Disord. 2009 Oct-Dec; 23(4):365-70.
  7. Kao AW, Price RW. Chemokine receptors, neural progenitor cells, and the AIDS dementia complex. J Infect Dis. 2004 Jul 15; 190(2):211-5.
  8. Kao AW, Yang C, Pessin JE. Functional comparison of the role of dynamin 2 splice variants on GLUT-4 endocytosis in 3T3L1 adipocytes. Am J Physiol Endocrinol Metab. 2000 May; 278(5):E825-31.
  9. Duan D, Li Q, Kao AW, Yue Y, Pessin JE, Engelhardt JF. Dynamin is required for recombinant adeno-associated virus type 2 infection. J Virol. 1999 Dec; 73(12):10371-6.
  10. Kao AW, Noda Y, Johnson JH, Pessin JE, Saltiel AR. Aldolase mediates the association of F-actin with the insulin-responsive glucose transporter GLUT4. J Biol Chem. 1999 Jun 18; 274(25):17742-7.
  11. Summers SA, Kao AW, Kohn AD, Backus GS, Roth RA, Pessin JE, Birnbaum MJ. The role of glycogen synthase kinase 3beta in insulin-stimulated glucose metabolism. J Biol Chem. 1999 Jun 18; 274(25):17934-40.
  12. Kao AW, Ceresa BP, Santeler SR, Pessin JE. Expression of a dominant interfering dynamin mutant in 3T3L1 adipocytes inhibits GLUT4 endocytosis without affecting insulin signaling. J Biol Chem. 1998 Sep 25; 273(39):25450-7.
  13. Ceresa BP, Kao AW, Santeler SR, Pessin JE. Inhibition of clathrin-mediated endocytosis selectively attenuates specific insulin receptor signal transduction pathways. Mol Cell Biol. 1998 Jul; 18(7):3862-70.
  14. Okada S, Kao AW, Ceresa BP, Blaikie P, Margolis B, Pessin JE. The 66-kDa Shc isoform is a negative regulator of the epidermal growth factor-stimulated mitogen-activated protein kinase pathway. J Biol Chem. 1997 Oct 31; 272(44):28042-9.
  15. Kao AW, Waters SB, Okada S, Pessin JE. Insulin stimulates the phosphorylation of the 66- and 52-kilodalton Shc isoforms by distinct pathways. Endocrinology. 1997 Jun; 138(6):2474-80.
  16. Waters SB, Chen D, Kao AW, Okada S, Holt KH, Pessin JE. Insulin and epidermal growth factor receptors regulate distinct pools of Grb2-SOS in the control of Ras activation. J Biol Chem. 1996 Jul 26; 271(30):18224-30.
  17. Bearer EL, DeGiorgis JA, Bodner RA, Kao AW, Reese TS. Evidence for myosin motors on organelles in squid axoplasm. Proc Natl Acad Sci U S A. 1993 Dec 1; 90(23):11252-6.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.