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Home > Doctors > Andrew J. Boyle

Andrew J. Boyle, M.D.

Interventional cardiologist

Dr. Andrew Boyle is a cardiologist who specializes in coronary artery disease at the UCSF Heart and Vascular Center. An interventional cardiologist, he performs cardiac catheterizations, coronary artery angioplasty and stenting as well as percutaneous closure of atrial septal defects (ASD) and patent foramen ovale (PFO). In addition to caring for patients, he studies adult stem cell therapies for heart disease and new imaging methods.

Boyle grew up in Australia, where he earned a medical degree at Monash University. He completed an internship, residency in internal medicine and fellowship in cardiology at St. Vincent's Hospital in Melbourne, Australia. In 2002, he received board certification in internal medicine and cardiology from the Royal Australasian College of Physicians. During his training, Boyle became interested in developing new techniques, particularly stem cell therapies, to prevent and treat heart failure after a heart attack. He also completed a doctorate degree at the University of Melbourne and Columbia University, New York. Subsequently, he completed a fellowship in interventional cardiology at Johns Hopkins University School of Medicine, where he studied stem cell therapeutics.

Conditions & Treatments

Clinics

Cardiovascular Care and Prevention Center at Mission Bay
535 Mission Bay Blvd. South
San Francisco, CA 94158
Phone: (415) 353-2873
Fax: (415) 353-2528

Hours: Monday to Friday
8 a.m. – 5 p.m.

More about Andrew J. Boyle

Education

Monash University School of Medicine, Australia 1994

Residencies

St. Vincent's Hospital, Australia, Internal Medicine 1998
St. Vincent's Hospital, Australia, Cardiology 2001

Fellowships

Johns Hopkins Hospital, Interventional Cardiology 2006

Selected Research and Publications

  1. Angeli FS, Zhang Y, Sievers R, Jun K, Yim S, Boyle A, Yeghiazarians Y. Injection of human bone marrow and mononuclear cell extract into infarcted mouse hearts results in functional improvement. Open Cardiovasc Med J. 2012; 6:38-43.
  2. Ye J, Boyle A, Shih H, Sievers RE, Zhang Y, Prasad M, Su H, Zhou Y, Grossman W, Bernstein HS, Yeghiazarians Y. Sca-1 cardiosphere-derived cells are enriched for isl1-expressing cardiac precursors and improve cardiac function after myocardial injury. PLoS One. 2012; 7(1):e30329.
  3. Wang TY, Masoudi FA, Messenger JC, Shunk KA, Boyle A, Brennan JM, Anderson HV, Anstrom KJ, Dai D, Peterson ED, Douglas PS, Rumsfeld JS. Percutaneous coronary intervention and drug-eluting stent use among patients =85 years of age in the United States. J Am Coll Cardiol. 2012 Jan 10; 59(2):105-12.
  4. Yeghiazarians Y, Gaur M, Zhang Y, Sievers RE, Ritner C, Prasad M, Boyle A, Bernstein HS. Myocardial improvement with human embryonic stem cell-derived cardiomyocytes enriched by p38MAPK inhibition. Cytotherapy. 2012 Feb; 14(2):223-31.
  5. Boyle AJ, Yeghiazarians Y, Shih H, Hwang J, Ye J, Sievers R, Zheng D, Palasubramaniam J, Palasubramaniam D, Karschimkus C, Whitbourn R, Jenkins A, Wilson AM. Myocardial production and release of MCP-1 and SDF-1 following myocardial infarction: differences between mice and man. J Transl Med. 2011; 9:150.
  6. Koskenvuo JW, Mirsky R, Zhang Y, Helenius H, Angeli FS, De Marco T, Boyle AJ, Yeghiazarians Y. Evidence of diminished coronary flow in pulmonary hypertension: explaining angina pectoris in this patient group? Clin Physiol Funct Imaging. 2011 Nov; 31(6):477-84.
  7. Mirsky R, Jahn S, Koskenvuo JW, Sievers RE, Yim SM, Ritner C, Bernstein HS, Angeli FS, Boyle AJ, De Marco T, Yeghiazarians Y. Treatment of pulmonary arterial hypertension with circulating angiogenic cells. Am J Physiol Lung Cell Mol Physiol. 2011 Jul; 301(1):L12-9.
  8. Boyle AJ, Shih H, Hwang J, Ye J, Lee B, Zhang Y, Kwon D, Jun K, Zheng D, Sievers R, Angeli F, Yeghiazarians Y, Lee R. Cardiomyopathy of aging in the mammalian heart is characterized by myocardial hypertrophy, fibrosis and a predisposition towards cardiomyocyte apoptosis and autophagy. Exp Gerontol. 2011 Jul; 46(7):549-59.
  9. Shih H, Lee B, Lee RJ, Boyle AJ. The aging heart and post-infarction left ventricular remodeling. J Am Coll Cardiol. 2011 Jan 4; 57(1):9-17.
  10. Angeli FS, Amabile N, Shapiro M, Mirsky R, Bartlett L, Zhang Y, Virmani R, Chatterjee K, Boyle A, Grossman W, Yeghiazarians Y. Cytokine combination therapy with erythropoietin and granulocyte colony stimulating factor in a porcine model of acute myocardial infarction. Cardiovasc Drugs Ther. 2010 Dec; 24(5-6):409-20.
  11. Zellner C, Ports TA, Yeghiazarians Y, Boyle AJ. Sterile radial artery granuloma after transradial procedures: a unique and avoidable complication. Catheter Cardiovasc Interv. 2010 Nov 1; 76(5):673-6.
  12. Yong CM, Sharma M, Ochoa V, Abnousi F, Roberts J, Bass NM, Niemann CU, Shiboski S, Prasad M, Tavakol M, Ports TA, Gregoratos G, Yeghiazarians Y, Boyle AJ. Multivessel coronary artery disease predicts mortality, length of stay, and pressor requirements after liver transplantation. Liver Transpl. 2010 Nov; 16(11):1242-8.
  13. Zellner C, Yeghiazarians Y, Ports TA, Ursell P, Boyle AJ. Sterile radial artery granuloma after transradial cardiac catheterization. Cardiovasc Revasc Med. 2011 May-Jun; 12(3):187-9.
  14. Hatzistergos KE, Quevedo H, Oskouei BN, Hu Q, Feigenbaum GS, Margitich IS, Mazhari R, Boyle AJ, Zambrano JP, Rodriguez JE, Dulce R, Pattany PM, Valdes D, Revilla C, Heldman AW, McNiece I, Hare JM. Bone marrow mesenchymal stem cells stimulate cardiac stem cell proliferation and differentiation. Circ Res. 2010 Oct 1; 107(7):913-22.
  15. Zhang Y, Sievers RE, Prasad M, Mirsky R, Shih H, Wong ML, Angeli FS, Ye J, Takagawa J, Koskenvuo JW, Springer ML, Grossman W, Boyle AJ, Yeghiazarians Y. Timing of bone marrow cell therapy is more important than repeated injections after myocardial infarction. Cardiovasc Pathol. 2011 Jul-Aug; 20(4):204-12.
  16. Heiss C, Jahn S, Taylor M, Real WM, Angeli FS, Wong ML, Amabile N, Prasad M, Rassaf T, Ottaviani JI, Mihardja S, Keen CL, Springer ML, Boyle A, Grossman W, Glantz SA, Schroeter H, Yeghiazarians Y. Improvement of endothelial function with dietary flavanols is associated with mobilization of circulating angiogenic cells in patients with coronary artery disease. J Am Coll Cardiol. 2010 Jul 13; 56(3):218-24.
  17. Angeli FS, Smith C, Amabile N, Shapiro M, Bartlett L, Virmani R, Chatterjee K, Boyle A, Grossman W, Yeghiazarians Y. Granulocyte colony stimulating factor in myocardial infarction with low ejection fraction. Cytokine. 2010 Sep; 51(3):278-85.
  18. Yeghiazarians Y, Khan M, Angeli FS, Zhang Y, Jahn S, Prasad M, Mirsky R, Shih H, Minasi P, Boyle A, Grossman W. Cytokine combination therapy with long-acting erythropoietin and granulocyte colony stimulating factor improves cardiac function but is not superior than monotherapy in a mouse model of acute myocardial infarction. J Card Fail. 2010 Aug; 16(8):669-78.
  19. Angeli FS, Amabile N, Burjonroppa S, Shapiro M, Bartlett L, Zhang Y, Virmani R, Chatterjee K, Boyle A, Grossman W, Yeghiazarians Y. Prolonged therapy with erythropoietin is safe and prevents deterioration of left ventricular systolic function in a porcine model of myocardial infarction. J Card Fail. 2010 Jul; 16(7):579-89.
  20. Koskenvuo JW, Mirsky R, Zhang Y, Angeli FS, Jahn S, Alastalo TP, Schiller NB, Boyle AJ, Chatterjee K, De Marco T, Yeghiazarians Y. A comparison of echocardiography to invasive measurement in the evaluation of pulmonary arterial hypertension in a rat model. Int J Cardiovasc Imaging. 2010 Jun; 26(5):509-18.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions by logging on to UCSF Profiles.

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