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Carlos Corvera, M.D., F.A.C.S.

Gastrointestinal cancer surgeon

Dr. Carlos Corvera is chief of the Liver, Biliary and Pancreatic Surgery Program at UCSF Medical Center and a cancer surgeon at the UCSF Helen Diller Comprehensive Cancer Center with expertise in the diagnosis and treatment of benign and malignant diseases of the liver, bile ducts, gallbladder and pancreas. He specializes in complex, conventional surgical procedures, and has developed innovations in minimally invasive, or laparoscopic, surgical techniques for the liver and pancreas.

Corvera graduated from the University of California, San Diego School of Medicine. He completed a general surgery residency at UCSF and a clinical fellowship in surgical oncology at Memorial Sloan-Kettering Cancer Center in New York City, where he completed a fellowship in hepatobiliary surgery. In his research, he focuses on the mechanisms of biliary tract fibrosis and inflammation. He is an associate professor of surgery at UCSF.

Clinics

Gastrointestinal Surgery and Oncology Clinic
1600 Divisadero St., Fourth Floor
San Francisco, CA 94143-1705
Phone: (415) 353-9888
Fax: (415) 353-9931

Hours: Monday to Friday
8 a.m. – 5 p.m.

Gastrointestinal Surgery at Parnassus
400 Parnassus Ave., Sixth Floor
San Francisco, CA 94143-0388
Phone: (415) 353-2161
Fax: (415) 353-2505

Hours: Monday to Friday
8 a.m. – 4:30 p.m.

Pancreas Center
1600 Divisadero St., Fourth Floor
San Francisco, CA 94143-1705
Phone (Pancreatic Cancer): (415) 353-9888
Fax: (415) 353-9931

Hours: Monday to Friday
8 a.m. — 5 p.m.

More about Carlos Corvera

Additional Languages

Spanish

Education

University of California, San Diego School of Medicine 1993

Residencies

UCSF Medical Center, General Surgery 2001

Fellowships

Memorial Sloan-Kettering Cancer Center, Surgical Oncology 2002
Memorial Sloan-Kettering Cancer Center, Hepatobiliary Surgery 2003

Selected Research and Publications

  1. Ho EY, Cozen ML, Shen H, Lerrigo R, Trimble E, Ryan JC, Corvera CU, Monto A. Expanded use of aggressive therapies improves survival in early and intermediate hepatocellular carcinoma. HPB (Oxford). 2014 Aug; 16(8):758-67.
  2. Jensen DD, Godfrey CB, Niklas C, Canals M, Kocan M, Poole DP, Murphy JE, Alemi F, Cottrell GS, Korbmacher C, Lambert NA, Bunnett NW, Corvera CU. The bile acid receptor TGR5 does not interact with -arrestins or traffic to endosomes but transmits sustained signals from plasma membrane rafts. J Biol Chem. 2013 Aug 9; 288(32):22942-60.
  3. Alemi F, Kwon E, Poole DP, Lieu T, Lyo V, Cattaruzza F, Cevikbas F, Steinhoff M, Nassini R, Materazzi S, Guerrero-Alba R, Valdez-Morales E, Cottrell GS, Schoonjans K, Geppetti P, Vanner SJ, Bunnett NW, Corvera CU. The TGR5 receptor mediates bile acid-induced itch and analgesia. J Clin Invest. 2013 Apr 1; 123(4):1513-30.
  4. Rajagopal S, Kumar DP, Mahavadi S, Bhattacharya S, Zhou R, Corvera CU, Bunnett NW, Grider JR, Murthy KS. Activation of G protein-coupled bile acid receptor, TGR5, induces smooth muscle relaxation via both Epac- and PKA-mediated inhibition of RhoA/Rho kinase pathway. Am J Physiol Gastrointest Liver Physiol. 2013 Mar 1; 304(5):G527-35.
  5. Alemi F, Poole DP, Chiu J, Schoonjans K, Cattaruzza F, Grider JR, Bunnett NW, Corvera CU. The receptor TGR5 mediates the prokinetic actions of intestinal bile acids and is required for normal defecation in mice. Gastroenterology. 2013 Jan; 144(1):145-54.
  6. Cottrell GS, Alemi F, Kirkland JG, Grady EF, Corvera CU, Bhargava A. Localization of calcitonin receptor-like receptor (CLR) and receptor activity-modifying protein 1 (RAMP1) in human gastrointestinal tract. Peptides. 2012 Jun; 35(2):202-11.
  7. Warne JP, Alemi F, Reed AS, Varonin JM, Chan H, Piper ML, Mullin ME, Myers MG, Corvera CU, Xu AW. Impairment of central leptin-mediated PI3K signaling manifested as hepatic steatosis independent of hyperphagia and obesity. Cell Metab. 2011 Dec 7; 14(6):791-803.
  8. Thompson M, Hiniker A, Duh QY, Corvera CU. Visual vignette. What is the diagnosis? Insulin-secreting tumor. Endocr Pract. 2011 Sep-Oct; 17(5):832.
  9. Alemi F, Kwon E, Chiu J, Aoki H, Stewart L, Corvera CU. Laparoscopic treatment of liver tumours using a two-needle probe bipolar radiofrequency ablation device. HPB (Oxford). 2011 Sep; 13(9):656-64.
  10. Alemi F, Kwon E, Freise C, Kang SM, Hirose R, Stewart L, Corvera CU. Hepatic surgery at a VA tertiary medical center: lessons learned. Am J Surg. 2010 Nov; 200(5):591-5.
  11. Russell JS, Sawhney R, Monto A, Nanavati S, Davoren JB, Aslam R, Corvera CU. Periprocedural complications by Child-Pugh class in patients undergoing transcatheter arterial embolization or chemoembolization to treat unresectable hepatocellular carcinoma at a VA medical center. Am J Surg. 2010 Nov; 200(5):659-64.
  12. Lavoie B, Balemba OB, Godfrey C, Watson CA, Vassileva G, Corvera CU, Nelson MT, Mawe GM. Hydrophobic bile salts inhibit gallbladder smooth muscle function via stimulation of GPBAR1 receptors and activation of KATP channels. J Physiol. 2010 Sep 1; 588(Pt 17):3295-305.
  13. Poole DP, Godfrey C, Cattaruzza F, Cottrell GS, Kirkland JG, Pelayo JC, Bunnett NW, Corvera CU. Expression and function of the bile acid receptor GpBAR1 (TGR5) in the murine enteric nervous system. Neurogastroenterol Motil. 2010 Jul; 22(7):814-25, e227-8.
  14. Parekh J, Corvera CU. Hemorrhagic cholecystitis. Arch Surg. 2010 Feb; 145(2):202-4.
  15. Kirkland JG, Godfrey CB, Garrett R, Kakar S, Yeh BM, Corvera CU. Reversible surgical model of biliary inflammation and obstructive jaundice in mice. J Surg Res. 2010 Dec; 164(2):221-7.
  16. Ozgediz D, Zheng J, Smith EB, Corvera CU. Abdominal actinomycosis after laparoscopic cholecystectomy: a rare complication of bile spillage. Surg Infect (Larchmt). 2009 Jun; 10(3):297-300.
  17. Chang TT, Corvera CU. Caudate split for open and laparoscopic liver resections. J Am Coll Surg. 2008 Dec; 207(6):e7-9.
  18. Ozgediz D, Smith EB, Zheng J, Otero J, Tabatabai ZL, Corvera CU. Basal cell carcinoma does metastasize. Dermatol Online J. 2008; 14(8):5.
  19. Chang TT, Sawhney R, Monto A, Davoren JB, Kirkland JG, Stewart L, Corvera CU. Implementation of a multidisciplinary treatment team for hepatocellular cancer at a Veterans Affairs Medical Center improves survival. HPB (Oxford). 2008; 10(6):405-11.
  20. Corvera CU, Blumgart LH, Akhurst T, DeMatteo RP, D'Angelica M, Fong Y, Jarnagin WR. 18F-fluorodeoxyglucose positron emission tomography influences management decisions in patients with biliary cancer. J Am Coll Surg. 2008 Jan; 206(1):57-65.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.