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Yerem Yeghiazarians, M.D.

Interventional cardiologist

Dr. Yerem Yeghiazarians is co-director of the Adult Cardiac Catheterization Laboratory, director of the Peripheral Interventional Cardiology Program and director of the UCSF Translational Cardiac Stem Cell Program. He is an expert in managing patients with coronary artery disease, acute coronary syndromes, valvular heart disease, cardiomyopathies, patent foramen ovale and peripheral arterial diseases.

Yeghiazarians earned an undergraduate degree from Brandeis University and a medical degree from the Johns Hopkins School of Medicine. He trained in internal medicine at Brigham and Women's Hospital, a teaching affiliate of Harvard Medical School, where he was chief medical resident and an instructor in medicine. He also completed general and interventional adult cardiology training at Brigham and Women's Hospital. At UCSF, he is an associate professor of cardiology.

Clinics

Cardiovascular Care and Prevention Center at Mission Bay
535 Mission Bay Blvd. South
San Francisco, CA 94158
Phone: (415) 353-2873
Fax: (415) 353-2528

Hours: Monday to Friday
8 a.m. – 5 p.m.

Heart Valve Disease Clinic
535 Mission Bay Blvd. South
San Francisco, CA 94158
Phone: (415) 353-9088
Fax: (415) 353-2528

Hours: Monday through Friday, 8 a.m. – 5 p.m.

Conditions & Treatments

More about Yerem Yeghiazarians

Additional Languages

Armenian
French
Persian

Education

Johns Hopkins University School of Medicine 1995

Residencies

Brigham and Women's Hospital-Harvard Medical School, Internal Medicine 1998

Fellowships

Brigham and Women's Hospital-Harvard Medical School, Cardiology 2003

Selected Research and Publications

  1. Ameri K, Rajah AM, Nguyen V, Sanders TA, Jahangiri A, Delay M, Donne M, Choi HJ, Tormos KV, Yeghiazarians Y, Jeffrey SS, Rinaudo PF, Rowitch DH, Aghi M, Maltepe E. Nuclear Localization of the Mitochondrial Factor HIGD1A during Metabolic Stress. PLoS One. 2013; 8(4):e62758.
  2. Ye J, Boyle AJ, Shih H, Sievers RE, Wang ZE, Gormley M, Yeghiazarians Y. CD45-positive cells are not an essential component in cardiosphere formation. Cell Tissue Res. 2013 Jan; 351(1):201-5.
  3. Majure DT, Hallaux M, Yeghiazarians Y, Boyle AJ. Topical nitroglycerin and lidocaine locally vasodilate the radial artery without affecting systemic blood pressure: A dose-finding phase I study. J Crit Care. 2012 Oct; 27(5):532.e9-532.e13.
  4. Angeli FS, Zhang Y, Sievers R, Jun K, Yim S, Boyle A, Yeghiazarians Y. Injection of human bone marrow and mononuclear cell extract into infarcted mouse hearts results in functional improvement. Open Cardiovasc Med J. 2012; 6:38-43.
  5. Koskenvuo JW, Sievers RE, Zhang Y, Angeli FS, Lee B, Shih H, Ye J, Boyle AJ, Yeghiazarians Y. Fractionation of mouse bone-marrow cells limits functional efficacy in non-reperfused mouse model of acute myocardial infarction. Ann Med. 2012 Dec; 44(8):829-35.
  6. Ye J, Boyle A, Shih H, Sievers RE, Zhang Y, Prasad M, Su H, Zhou Y, Grossman W, Bernstein HS, Yeghiazarians Y. Sca-1+ cardiosphere-derived cells are enriched for Isl1-expressing cardiac precursors and improve cardiac function after myocardial injury. PLoS One. 2012; 7(1):e30329.
  7. Yeghiazarians Y, Gaur M, Zhang Y, Sievers RE, Ritner C, Prasad M, Boyle A, Bernstein HS. Myocardial improvement with human embryonic stem cell-derived cardiomyocytes enriched by p38MAPK inhibition. Cytotherapy. 2012 Feb; 14(2):223-31.
  8. Aschbacher K, Chen Q, Varga M, Haddad DJ, Yeghiazarians Y, Epel E, Wolkowitz OM, Springer ML. Higher fasting glucose levels are associated with reduced circulating angiogenic cell migratory capacity among healthy individuals. Am J Cardiovasc Dis. 2012; 2(1):12-9.
  9. Chen S, Law CS, Grigsby CL, Olsen K, Hong TT, Zhang Y, Yeghiazarians Y, Gardner DG. Cardiomyocyte-specific deletion of the vitamin D receptor gene results in cardiac hypertrophy. Circulation. 2011 Oct 25; 124(17):1838-47.
  10. Wang X, Takagawa J, Lam VC, Haddad DJ, Tobler DL, Mok PY, Zhang Y, Clifford BT, Pinnamaneni K, Saini SA, Su R, Bartel MJ, Sievers RE, Carbone L, Kogan S, Yeghiazarians Y, Hermiston M, Springer ML. Donor myocardial infarction impairs the therapeutic potential of bone marrow cells by an interleukin-1-mediated inflammatory response. Sci Transl Med. 2011 Sep 14; 3(100):100ra90.
  11. Boyle AJ, Yeghiazarians Y, Shih H, Hwang J, Ye J, Sievers R, Zheng D, Palasubramaniam J, Palasubramaniam D, Karschimkus C, Whitbourn R, Jenkins A, Wilson AM. Myocardial production and release of MCP-1 and SDF-1 following myocardial infarction: differences between mice and man. J Transl Med. 2011; 9:150.
  12. Koskenvuo JW, Mirsky R, Zhang Y, Helenius H, Angeli FS, De Marco T, Boyle AJ, Yeghiazarians Y. Evidence of diminished coronary flow in pulmonary hypertension: explaining angina pectoris in this patient group? Clin Physiol Funct Imaging. 2011 Nov; 31(6):477-84.
  13. Ng R, Yeghiazarians Y. Post Myocardial Infarction Cardiogenic Shock: A Review of Current Therapies. J Intensive Care Med. 2011 Jul 11.
  14. Lao D, Parasher PS, Cho KC, Yeghiazarians Y. Atherosclerotic renal artery stenosis--diagnosis and treatment. Mayo Clin Proc. 2011 Jul; 86(7):649-57.
  15. Mirsky R, Jahn S, Koskenvuo JW, Sievers RE, Yim SM, Ritner C, Bernstein HS, Angeli FS, Boyle AJ, De Marco T, Yeghiazarians Y. Treatment of pulmonary arterial hypertension with circulating angiogenic cells. Am J Physiol Lung Cell Mol Physiol. 2011 Jul; 301(1):L12-9.
  16. Boyle AJ, Shih H, Hwang J, Ye J, Lee B, Zhang Y, Kwon D, Jun K, Zheng D, Sievers R, Angeli F, Yeghiazarians Y, Lee R. Cardiomyopathy of aging in the mammalian heart is characterized by myocardial hypertrophy, fibrosis and a predisposition towards cardiomyocyte apoptosis and autophagy. Exp Gerontol. 2011 Jul; 46(7):549-59.
  17. Glenn DJ, Wang F, Nishimoto M, Cruz MC, Uchida Y, Holleran WM, Zhang Y, Yeghiazarians Y, Gardner DG. A murine model of isolated cardiac steatosis leads to cardiomyopathy. Hypertension. 2011 Feb; 57(2):216-22.
  18. Hoffmayer KS, Zellner C, Kwan DM, Konety S, Foster E, Moore P, Yeghiazarians Y. Closure of a para-valvular aortic leak: with the use of 2 AMPLATZER devices and real-time 2- and 3-dimensional transesophageal echocardiography. Tex Heart Inst J. 2011; 38(1):81-4.
  19. Angeli FS, Amabile N, Shapiro M, Mirsky R, Bartlett L, Zhang Y, Virmani R, Chatterjee K, Boyle A, Grossman W, Yeghiazarians Y. Cytokine combination therapy with erythropoietin and granulocyte colony stimulating factor in a porcine model of acute myocardial infarction. Cardiovasc Drugs Ther. 2010 Dec; 24(5-6):409-20.
  20. Ochoa VM, Yeghiazarians Y. Subclavian artery stenosis: a review for the vascular medicine practitioner. Vasc Med. 2011 Feb; 16(1):29-34.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions by logging on to UCSF Profiles.