Congenital Heart Disease

Transposition of Great Arteries

Signs and Symptoms
Diagnosis
Treatment

Treatment

Early treatment is aimed at maintaining blood circulation. A medication called prostaglandin may be used to keep the ductus arteriosus open.

Another procedure, called an atrial septostomy, may be used to enlarge an atrial septal defect. In this procedure, performed in our Cardiac Catheterization Laboratory, a thin plastic tube called a catheter is inserted into a blood vessel in the groin and then directed to the heart and the site of the foramen ovale. A balloon on the tip of the catheter is inflated and then pulled back to enlarge the hole.

Permanent treatment requires a surgical procedure to switch the arteries to their proper places. This operation, called an arterial switch operation, is done within the first few weeks of life. It is an open-heart procedure that requires a temporary stopping of the baby's heart while a heart-lung machine handles respiration and blood circulation. Any abnormal holes between the ventricles or atria also are closed.

As part of the procedure, the coronary arteries — the arteries that supply blood to the heart — have to be taken off their normal position on the aorta and transplanted into the new "aorta" that now carries oxygenated blood from the left ventricle around the body. Rarely, this may be lead to problems that require further procedures.

Reviewed by health care specialists at UCSF Children's Hospital.
Last updated May 8, 2007