Vein of Galen Malformation

Vein of Galen malformations (VOGMs) belong to a group of disorders known as cerebral vascular malformations, which are conditions affecting the blood vessels in the brain. Vascular malformations can involve the arteries, the blood vessels that carry blood to the body, or the veins, the blood vessels that return blood to the heart. VOGM is a rare type of vascular malformation of the brain that develops before birth and often affects newborns.

A VOGM occurs when there is an abnormal connection between arteries and the deep draining veins. Normally, these arteries and veins are connected by capillaries, which monitor and slow blood flow through the brain, allowing for the exchange of oxygen and nutrients. However, because a VOGM does not have capillaries, the blood flow becomes very fast, making the heart work harder. This can result in heart failure, which is the most common concern in newborns. The malformation also can interfere with normal drainage of the fluid produced by the brain, called the cerebrospinal fluid, causing this fluid to accumulate and leading to a condition called hydrocephalus. If left untreated, a VOGM also can cause problems with mental development, resulting in retardation or even death.

Our UCSF Pediatric Stroke and Cerebrovascular Disease Center is staffed by the world's leading experts in stroke and cerebrovascular disease among children. A team of experts specializing in malformations that affect blood vessels in the brain, work together with you and your family to develop the best possible treatment plan for your child. This team includes a neurologist, neurosurgeon and interventional neuroradiologist.

For more information or to make an appointment, please call:
Child Neurology Clinic (415) 353-2525

Reviewed by health care specialists at UCSF Children's Hospital.
Last updated August 15, 2007