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Clay Johnston, M.D.


Dr. Claiborne Johnston is a neurologist who treats patients with cerebral aneurysms, vascular malformations and stroke. Most of the care he provides occurs in the hospital, including the Neurological Intensive Care Unit, but he also provides follow-up care for patients with complex neurovascular disorders in the Neurovascular Disease and Stroke Center.

Johnston earned a medical degree at Harvard Medical School and completed a residency in neurology as well as a fellowship in neurovascular service at UCSF. He earned a doctorate in epidemiology at the University of California at Berkeley. At UCSF, Johnston is associate vice chancellor of research, director of the Clinical and Translational Science Institute, director of the hospital Stroke Service and a professor of neurology and epidemiology.


Neurovascular Disease and Stroke Center
400 Parnassus Ave., Eighth Floor
San Francisco, CA 94143
Phone: (415) 353-8897
Fax: (415) 353-8705

Hours: Monday to Friday
8:30 a.m. – 5 p.m.

Conditions & Treatments

More about Clay Johnston


Harvard Medical School 1992


UCSF, Neurology 1996


UCSF, Neurovascular 1998

Selected Research and Publications

  1. Wang Y, Johnston SC, Wang Y. Clopidogrel with aspirin in minor stroke or transient ischemic attack. N Engl J Med. 2013 Oct 3; 369(14):1376-7.
  2. Saposnik G, Johnston SC, Ovbiagele B. Response to letter regarding article, "Predicting clinical outcomes after thrombolysis using the iScore: results from the Virtual International Stroke Trials Archive". Stroke. 2013 Nov; 44(11):e155.
  3. Saposnik G, Johnston SC, Raptis S, Ovbiagele B, Fisher M. Stroke journal: what is being published to advance the field? Stroke. 2013 Sep; 44(9):2644-9.
  4. Hauser SL, Johnston SC. Living in the time of sequestration. Ann Neurol. 2013 Jul; 74(1):A5-6.
  5. Wang Y, Wang Y, Zhao X, Liu L, Wang D, Wang C, Wang C, Li H, Meng X, Cui L, Jia J, Dong Q, Xu A, Zeng J, Li Y, Wang Z, Xia H, Johnston SC. Clopidogrel with aspirin in acute minor stroke or transient ischemic attack. N Engl J Med. 2013 Jul 4; 369(1):11-9.
  6. Johnston SC, Hauser SL. The dangers of clinical conviction: an "M&M" of endovascular therapies for stroke. Ann Neurol. 2013 Jun; 73(6):A5-6.
  7. Ovbiagele B, Goldstein LB, Higashida RT, Howard VJ, Johnston SC, Khavjou OA, Lackland DT, Lichtman JH, Mohl S, Sacco RL, Saver JL, Trogdon JG. Forecasting the future of stroke in the United States: a policy statement from the American Heart Association and American Stroke Association. Stroke. 2013 Aug; 44(8):2361-75.
  8. Hauser SL, Josephson SA, Johnston SC. Multiple sclerosis: monotherapy rules. Ann Neurol. 2013 Mar; 73(3):A5-6.
  9. Johnston SC, Josephson SA, Hauser SL. Are relative value units hurting healthcare? Ann Neurol. 2013 Feb; 73(2):A5-6.
  10. Nikneshan D, Raptis R, Pongmoragot J, Zhou L, Johnston SC, Saposnik G. Predicting clinical outcomes and response to thrombolysis in acute stroke patients with diabetes. Diabetes Care. 2013 Jul; 36(7):2041-7.
  11. Kim AS, Johnston SC. Is hypertension the key to reaching the healthy people 2000 goals by 2020? JAMA Intern Med. 2013 Jan 14; 173(1):51-3.
  12. Navi BB, Kamel H, Shah MP, Grossman AW, Wong C, Poisson SN, Whetstone WD, Josephson SA, Johnston SC, Kim AS. The use of neuroimaging studies and neurological consultation to evaluate dizzy patients in the emergency department. Neurohospitalist. 2013 Jan; 3(1):7-14.
  13. Hauser SL, Johnston SC. DSM-V: psychodrama on the public stage. Ann Neurol. 2013 Jan; 73(1):A5-6.
  14. Wang A, Al-Kuhlani M, Johnston SC, Ojcius DM, Chou J, Dean D. Transcription factor complex AP-1 mediates inflammation initiated by Chlamydia pneumoniae infection. Cell Microbiol. 2013 May; 15(5):779-94.
  15. Josephson SA, Johnston SC, Hauser SL. Electronic medical records and the academic neurologist: when carrots turn into sticks. Ann Neurol. 2012 Dec; 72(6):A5-6.
  16. Kamel H, Navi BB, Elijovich L, Josephson SA, Yee AH, Fung G, Johnston SC, Smith WS. Pilot randomized trial of outpatient cardiac monitoring after cryptogenic stroke. Stroke. 2013 Feb; 44(2):528-30.
  17. Saposnik G, Guzik AK, Reeves M, Ovbiagele B, Johnston SC. Stroke Prognostication using Age and NIH Stroke Scale: SPAN-100. Neurology. 2013 Jan 1; 80(1):21-8.
  18. Hauser SL, Josephson SA, Johnston SC. Deciphering the signature injury. Ann Neurol. 2012 Nov; 72(5):A5-6.
  19. Saposnik G, Demchuk A, Tu JV, Johnston SC. The iScore predicts efficacy and risk of bleeding in the National Institute of Neurological disorders and Stroke Tissue Plasminogen Activator Stroke Trial. J Stroke Cerebrovasc Dis. 2013 Aug; 22(6):876-82.
  20. Navi BB, Kamel H, Shah MP, Grossman AW, Wong C, Poisson SN, Whetstone WD, Josephson SA, Johnston SC, Kim AS. Rate and predictors of serious neurologic causes of dizziness in the emergency department. Mayo Clin Proc. 2012 Nov; 87(11):1080-8.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.