Corticobasal Degeneration
Treatment

Currently, there are no treatments to slow the progress of corticobasal degeneration (CBD). Instead, individual symptoms are targeted with specific medications or therapy. For example, rigidity and difficulty walking may partially respond to treatments for Parkinson's disease.

Muscle contractions and and twitching may respond to muscle relaxants or anti-seizure medications.

Memory and behavior problems may respond to treatments for Alzheimer's disease or depression.

Other therapies include:

• Occupational therapy may be used to design equipment that supports the activities of daily living and maintains functional independence.
• Physical therapy is important for maintaining a patient's range of motion. This may prevent pain and contraction or the shortening of muscles as well as help maintain mobility.
• Speech therapy may be recommended to improve articulation and volume of the voice.

The UCSF Memory and Aging Center is involved in research to better understand the cause and course of the disease, which has led to counseling, support and medications to treat symptoms.

Reviewed by health care specialists at UCSF Medical Center.