Multiple Myeloma
Signs and Symptoms

Symptoms of multiple myeloma depend on how advanced the disease has become. In the earliest stages, a person may not have any symptoms.

When symptoms do occur, patients commonly experience:

• Bone pain (often in the back or ribs)
• Broken bones
• Weakness
• Fatigue
• Weight loss
• Repeated infections

When the disease is advanced, symptoms may include:

• Nausea
• Vomiting
• Constipation
• Problems with urination
• Weakness or numbness in the legs

These are not sure signs of multiple myeloma, however — they can be caused by other medical problems. If you experience these symptoms, see a doctor as soon as possible. Only a health professional can determine what is causing a patient's symptoms.

Reviewed by health care specialists at UCSF Medical Center.