The treatment for recurrent pregnancy loss (RPL) depends on what's causing the condition.
In cases where an abnormality of chromosome structure is causing RPL, one possible therapy is in vitro fertilization (IVF), with biopsy and chromosomal evaluation of each embryo, called pre-implantation genetic diagnosis.
Diagnostic tests such as hysterosalpingograms, saline sonohysterograms and hysteroscopy (an endoscopic inspection of the uterus) can be used to evaluate the uterine cavity. Many abnormalities within the uterine cavity can be corrected with minor surgery.
Anti-phospholipid antibody syndrome (APS) has been shown to respond to treatment with blood thinning medications.
Currently, there is no evidence that blood thinning medications can prevent miscarriage, although studies are ongoing.
In cases of uncontrolled diabetes or thyroid gland dysfunction, correcting the hormonal imbalances is recommended.
In the search for a solution for RPL, several tests and therapies have been used that are not proven to be helpful. These include:
Reviewed by health care specialists at UCSF Medical Center.