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P. Daniel Knott, M.D.

Facial plastic, aesthetic and reconstructive surgeon

Dr. P. Daniel Knott is director of Facial Plastic, Aesthetic and Reconstructive Surgery in Otolaryngology-Head and Neck Surgery at UCSF Medical Center. Knott, who joined UCSF in 2011 after 10 years at the Cleveland Clinic, has training and experience in facial aesthetics and microvascular surgery. His expertise includes treatment of facial paralysis, facial rejuvenation, reconstruction of facial cutaneous malignancies, minimally invasive facial soft tissue augmentation, rhinoplasty and free tissue transfer.

In his research, he is helping develop new methods for palatal and orbito-maxillary reconstruction, microvascular treatment of osteonecrosis and cartilage bioengineering. He has won several national awards for his research, which includes studies of head and neck tissue transplantation. Knott earned a medical degree at the School of Medicine at the University of California, San Diego and completed a five-year surgical residency at the Cleveland Clinic in otolaryngology-head and neck surgery. He also completed a fellowship in facial plastic and reconstructive surgery at UCLA Medical Center. He's an associate professor of otolaryngology at UCSF.


Facial Plastic and Reconstructive Surgery
2330 Post St., Fifth Floor
San Francisco, CA 94115
Phone: (415) 353-9500
Fax: (415) 885-7800

Hours: Monday to Friday
8 a.m. – 5 p.m.

Head and Neck Surgery Cancer Clinic
1825 Fourth St., Fourth Floor
San Francisco, CA 94158
Phone: (415) 885–7528
Fax: (415) 885–7711

Hours: Monday to Friday
8 a.m. – 5 p.m.

Conditions & Treatments

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UC San Diego School of Medicine 2000


Cleveland Clinic Foundation Medical Center 2006


UCLA Medical Center 2007

Selected Research and Publications

  1. Xu X, Wilschut KJ, Kouklis G, Tian H, Hesse R, Garland C, Sbitany H, Hansen S, Seth R, Knott PD, Hoffman WY, Pomerantz JH. Human Satellite Cell Transplantation and Regeneration from Diverse Skeletal Muscles. Stem Cell Reports. 2015 Sep 8; 5(3):419-34.
  2. Markey J, Knott PD, Fritz MA, Seth R. Recent advances in head and neck free tissue transfer. Curr Opin Otolaryngol Head Neck Surg. 2015 Aug; 23(4):297-301.
  3. Markey J, Seth R, Knott PD. Safety of cyanoacrylate-based adhesives in creating layered septal cartilage grafts during open structure septorhinoplasty. Am J Otolaryngol. 2015 Jul-Aug; 36(4):499-502.
  4. Revenaugh PC, Fritz MA, Haffey TM, Seth R, Markey J, Knott PD. Minimizing morbidity in microvascular surgery: small-caliber anastomotic vessels and minimal access approaches. JAMA Facial Plast Surg. 2015 Jan 1; 17(1):44-8.
  5. Kram YA, Russell MS, Russell MD, Knott PD. Single-stage, double-conduit microvascular pharyngotracheal reconstruction. J Reconstr Microsurg. 2015 Mar; 31(3):233-5.
  6. Cannady SB, Rosenthal EL, Knott PD, Fritz M, Wax MK. Free tissue transfer for head and neck reconstruction: a contemporary review. JAMA Facial Plast Surg. 2014 Sep-Oct; 16(5):367-73.
  7. Revenaugh PC, Knott PD, Alam DS, Kmiecik J, Fritz MA. Voice outcomes following reconstruction of laryngopharyngectomy defects using the radial forearm free flap and the anterolateral thigh free flap. Laryngoscope. 2014 Feb; 124(2):397-400.
  8. Revenaugh PC, Waters HH, Scharpf J, Knott PD, Fritz MA. Suprastomal cutaneous monitoring paddle for free flap reconstruction of laryngopharyngectomy defects. JAMA Facial Plast Surg. 2013 Jul-Aug; 15(4):287-91.
  9. Punthakee X, Zaghi S, Nabili V, Knott PD, Blackwell KE. Effects of salivary bypass tubes on fistula and stricture formation. JAMA Facial Plast Surg. 2013 May; 15(3):219-25.
  10. Rayess HM, Revenaugh PC, Benninger MS, Knott PD. Predictive factors for patient outcomes following open bedside tracheotomy. Laryngoscope. 2013 Apr; 123(4):923-8.
  11. Revenaugh PC, Knott PD, McBride JM, Fritz MA. Motor Nerve to the Vastus Lateralis. Arch Facial Plast Surg. 2012 Apr 16.
  12. Revenaugh PC, Knott PD, Scharpf J, Fritz MA. Simultaneous anterolateral thigh flap and temporalis tendon transfer to optimize facial form and function after radical parotidectomy. Arch Facial Plast Surg. 2012 Mar-Apr; 14(2):104-9.
  13. Shipchandler TZ, Waters HH, Knott PD, Fritz MA. Orbitomaxillary reconstruction using the layered fibula osteocutaneous flap. Arch Facial Plast Surg. 2012 Mar-Apr; 14(2):110-5.
  14. Knott PD, Hicks D, Braun W, Strome M. A 12-year perspective on the world's first total laryngeal transplant. Transplantation. 2011 Apr 15; 91(7):804-5.
  15. Seth R, Nabili V, Fritz MA, Alam DS, Knott PD. Volume-directed facial soft tissue deficit reconstruction. Facial Plast Surg. 2010 Dec; 26(6):494-503.
  16. Seth R, Futran ND, Alam DS, Knott PD. Outcomes of vascularized bone graft reconstruction of the mandible in bisphosphonate-related osteonecrosis of the jaws. Laryngoscope. 2010 Nov; 120(11):2165-71.
  17. Revenaugh PC, Seth R, Pavlovich JB, Knott PD, Batra PS. Minimally invasive endoscopic resection of sinonasal undifferentiated carcinoma. Am J Otolaryngol. 2011 Nov-Dec; 32(6):464-9.
  18. Makin V, Hatipoglu B, Hamrahian AH, Arrossi AV, Knott PD, Lee JH, Sade B. Spontaneous cerebrospinal fluid rhinorrhea as the initial presentation of growth hormone-secreting pituitary adenoma. Am J Otolaryngol. 2011 Sep-Oct; 32(5):433-7.
  19. Seth R, Waters HH, Knott PD. Vascularized bone graft reconstruction of the temporomandibular joint using the tunneled, anchored suture technique. Laryngoscope. 2010; 120 Suppl 4:S236.
  20. Knott PD, Newman J, Keller GS, Apfelberg DB. A novel bioabsorbable device for facial suspension and rejuvenation. Arch Facial Plast Surg. 2009 Mar-Apr; 11(2):129-35.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.