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David Wilson, M.D.



Columbia College at Chicago School of Medicine 2004


UCSF Medical Center 2009


UCSF Medical Center 2011

Selected Research and Publications

  1. Wilson DM, Apps J, Bailey N, Bamford MJ, Beresford IJ, Briggs MA, Calver AR, Crook B, Davis RP, Davis S, Dean DK, Harris L, Heightman TD, Panchal T, Parr CA, Quashie N, Steadman JG, Schogger J, Sehmi SS, Stean TO, Takle AK, Trail BK, White T, Witherington J, Worby A, Medhurst AD. The discovery of the benzazepine class of histamine H3 receptor antagonists. Bioorg Med Chem Lett. 2013 Dec 15; 23(24):6897-901.
  2. Wilson DM, Apps J, Bailey N, Bamford MJ, Beresford IJ, Brackenborough K, Briggs MA, Brough S, Calver AR, Crook B, Davis RK, Davis RP, Davis S, Dean DK, Harris L, Heslop T, Holland V, Jeffrey P, Panchal TA, Parr CA, Quashie N, Schogger J, Sehmi SS, Stean TO, Steadman JG, Trail B, Wald J, Worby A, Takle AK, Witherington J, Medhurst AD. Identification of clinical candidates from the benzazepine class of histamine H3 receptor antagonists. Bioorg Med Chem Lett. 2013 Dec 15; 23(24):6890-6.
  3. Kirkali G, Jaruga P, Reddy PT, Tona A, Nelson BC, Li M, Wilson DM, Dizdaroglu M. Identification and quantification of DNA repair protein apurinic/apyrimidinic endonuclease 1 (APE1) in human cells by liquid chromatography/isotope-dilution tandem mass spectrometry. PLoS One. 2013; 8(7):e69894.
  4. Kostylev M, Wilson D. Two-parameter kinetic model based on a time-dependent activity coefficient accurately describes enzymatic cellulose digestion. Biochemistry. 2013 Aug 20; 52(33):5656-64.
  5. Kassick AJ, Jiang J, Bunda J, Wilson D, Bao J, Lu H, Lin P, Ball RG, Doss GA, Tong X, Tsao KL, Wang H, Chicchi G, Karanam B, Tschirret-Guth R, Samuel K, Hora DF, Kumar S, Madeira M, Eng W, Hargreaves R, Purcell M, Gantert L, Cook J, Devita RJ, Mills SG. 2-[(3aR,4R,5S,7aS)-5-{(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]-2-hydroxyethoxy}-4-(2-methylphenyl)octahydro-2H-isoindol-2-yl]-1,3-oxazol-4(5H)-one: A Potent Human NK1 Receptor Antagonist with Multiple Clearance Pathways. J Med Chem. 2013 Jul 25; 56(14):5940-8.
  6. Jiménez-Díaz MB, Viera S, Ibáñez J, Mulet T, Magán-Marchal N, Garuti H, Gómez V, Cortés-Gil L, Martínez A, Ferrer S, Fraile MT, Calderón F, Fernández E, Shultz LD, Leroy D, Wilson DM, García-Bustos JF, Gamo FJ, Angulo-Barturen I. A new in vivo screening paradigm to accelerate antimalarial drug discovery. PLoS One. 2013; 8(6):e66967.
  7. Wilson DM, Lemon CH. Modulation of central gustatory coding by temperature. J Neurophysiol. 2013 Sep; 110(5):1117-29.
  8. Illuzzi JL, Harris NA, Manvilla BA, Kim D, Li M, Drohat AC, Wilson DM. Functional assessment of population and tumor-associated APE1 protein variants. PLoS One. 2013; 8(6):e65922.
  9. Iyama T, Wilson DM. DNA repair mechanisms in dividing and non-dividing cells. DNA Repair (Amst). 2013 Aug; 12(8):620-36.
  10. Sykora P, Wilson DM, Bohr VA. Base excision repair in the mammalian brain: Implication for age related neurodegeneration. Mech Ageing Dev. 2013 Oct; 134(10):440-8.
  11. Wilson DM, Bohr VA. Special issue on the segmental progeria Cockayne syndrome. Mech Ageing Dev. 2013 May-Jun; 134(5-6):159-60.
  12. Keshari KR, Sai V, Wang ZJ, Vanbrocklin HF, Kurhanewicz J, Wilson DM. Hyperpolarized [1-13C]dehydroascorbate MR spectroscopy in a murine model of prostate cancer: comparison with 18F-FDG PET. J Nucl Med. 2013 Jun; 54(6):922-8.
  13. Keshari KR, Sriram R, Van Criekinge M, Wilson DM, Wang ZJ, Vigneron DB, Peehl DM, Kurhanewicz J. Metabolic reprogramming and validation of hyperpolarized 13C lactate as a prostate cancer biomarker using a human prostate tissue slice culture bioreactor. Prostate. 2013 Aug; 73(11):1171-81.
  14. McNeill DR, Paramasivam M, Baldwin J, Huang J, Vyjayanti VN, Seidman MM, Wilson DM. NEIL1 responds and binds to psoralen-induced DNA interstrand crosslinks. J Biol Chem. 2013 May 3; 288(18):12426-36.
  15. Koelsch BL, Keshari KR, Peeters TH, Larson PE, Wilson DM, Kurhanewicz J. Diffusion MR of hyperpolarized 13C molecules in solution. Analyst. 2013 Feb 21; 138(4):1011-4.
  16. Dozier CL, Iwata BA, Wilson DM, Thomason-Sassi JL, Roscoe EM. Does supplementary reinforcement of stereotypy facilitate extinction? J Appl Behav Anal. 2013; 46(1):242-55.
  17. Sykora P, Yang JL, Ferrarelli LK, Tian J, Tadokoro T, Kulkarni A, Weissman L, Keijzers G, Wilson DM, Mattson MP, Bohr VA. Modulation of DNA base excision repair during neuronal differentiation. Neurobiol Aging. 2013 Jul; 34(7):1717-27.
  18. Harbour JW, Wilson D, Finger PT, Worley LA, Onken MD. Gene expressing profiling of iris melanomas. Ophthalmology. 2013 Jan; 120(1):213, 213.e1-3.
  19. Calderón F, Wilson DM, Gamo FJ. Antimalarial drug discovery: recent progress and future directions. Prog Med Chem. 2013; 52:97-151.
  20. Keshari KR, Sriram R, Koelsch BL, Van Criekinge M, Wilson DM, Kurhanewicz J, Wang ZJ. Hyperpolarized 13C-pyruvate magnetic resonance reveals rapid lactate export in metastatic renal cell carcinomas. Cancer Res. 2013 Jan 15; 73(2):529-38.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.