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Edward Chang, M.D.

Neurosurgeon

Dr. Edward Chang is a neurosurgeon with expertise in treating intractable epilepsy, trigeminal neuralgia, movement disorders and brain tumors in adults. He specializes in advanced brain mapping methods, including awake speech and motor mapping, to safely perform surgery in the brain. He also has extensive experience with implantable devices for neuromodulation.

Chang's research focuses upon the brain mechanisms for human speech, movement and cognition. He is faculty in the Center for Integrative Neuroscience and the Neuroscience and Bioengineering graduate programs. He co-directs the Center for Neural Engineering & Prostheses at UC Berkeley and UCSF, which brings together engineering, neuroscience, neurology and neurosurgery to develop state-of-the-art biomedical devices to restore function for patients with neurological disabilities such as paralysis and speech disorders. He earned a medical degree and completed neurosurgery residency training at UCSF. Chang is an associate professor of neurological surgery and physiology at UCSF.

Read a Q&A with Chang about surgical treatments for epilepsy.

Clinics

Epilepsy Center
400 Parnassus Ave., Eighth Floor
San Francisco, CA 94143
Phone: (415) 353-2437
Fax: (415) 353-2837

Hours: Monday to Friday
8 a.m. – 5 p.m.

Neurosurgery Clinic
400 Parnassus Ave., Eighth Floor
San Francisco, CA 94143
Phone: (415) 353-7500
Fax: (415) 353-2889

Hours: Monday to Friday
8 a.m. – 4:30 p.m.

Trigeminal Neuralgia Clinic
400 Parnassus Ave., Eighth Floor
San Francisco, CA 94143
Medical Management:
(415) 353-2892
Surgical Management:
(415) 353-2241
Medical Management Fax:
(415) 353-2898
Surgical Management Fax :
(415) 353-2889

Hours: Monday to Friday
8 a.m. – 5 p.m.

Conditions & Treatments

  • Gamma Knife
  • Glossopharyngeal Neuralgia
  • Hemifacial Spasm

More about Edward Chang

Education

UCSF School of Medicine 2004

Residencies

UCSF Medical Center, Neurosurgery 2010

Selected Research and Publications

  1. Cheng JS, Lim DA, Chang EF, Barbaro NM. A review of percutaneous treatments for trigeminal neuralgia. Neurosurgery. 2014 Mar; 10 Suppl 1:25-33.
  2. Dürschmid S, Quandt F, Krämer UM, Hinrichs H, Heinze HJ, Schulz R, Pannek H, Chang EF, Knight RT. Oscillatory dynamics track motor performance improvement in human cortex. PLoS One. 2014; 9(2):e89576.
  3. Englot DJ, Chang EF. Rates and predictors of seizure freedom in resective epilepsy surgery: an update. Neurosurg Rev. 2014 Jul; 37(3):389-405.
  4. Mesgarani N, Cheung C, Johnson K, Chang EF. Phonetic feature encoding in human superior temporal gyrus. Science. 2014 Feb 28; 343(6174):1006-10.
  5. Englot DJ, Lee AT, Tsai C, Halabi C, Barbaro NM, Auguste KI, Garcia PA, Chang EF. Seizure types and frequency in patients who "fail" temporal lobectomy for intractable epilepsy. Neurosurgery. 2013 Nov; 73(5):838-44; quiz 844.
  6. Tate MC, Guo L, McEvoy J, Chang EF. Safety and efficacy of motor mapping utilizing short pulse train direct cortical stimulation. Stereotact Funct Neurosurg. 2013; 91(6):379-85.
  7. Wissel T, Pfeiffer T, Frysch R, Knight RT, Chang EF, Hinrichs H, Rieger JW, Rose G. Hidden Markov model and support vector machine based decoding of finger movements using electrocorticography. J Neural Eng. 2013 Oct; 10(5):056020.
  8. Edwards E, Chang EF. Syllabic (~2-5 Hz) and fluctuation (~1-10 Hz) ranges in speech and auditory processing. Hear Res. 2013 Nov; 305:113-34.
  9. Conant D, Bouchard KE, Chang EF. Speech map in the human ventral sensory-motor cortex. Curr Opin Neurobiol. 2014 Feb; 24(1):63-7.
  10. Burneo JG, Sirven JI, Kiesel LW, Vecht CJ, Jehi L, Chung SS, Uhm J, Politsky JM, Chang EF, Husain AM, Tatum WO, Meador KJ, Noe K, Hesdorffer DC, Herman ST, Wiebe S, Engel J, Schrader S, Parko KL, Dichter MA, Kwan P, Kossoff E, Sperling MR. Managing common complex symptomatic epilepsies: tumors and trauma: american epilepsy society - 2012 annual course summary. Epilepsy Curr. 2013 Sep; 13(5):232-5.
  11. Wang DD, Ouyang D, Englot DJ, Rolston JD, Molinaro AM, Ward M, Chang EF. Trends in surgical treatment for trigeminal neuralgia in the United States of America from 1988 to 2008. J Clin Neurosci. 2013 Nov; 20(11):1538-45.
  12. Jahangiri A, Wagner JR, Pekmezci M, Hiniker A, Chang EF, Kunwar S, Blevins L, Aghi MK. A comprehensive long-term retrospective analysis of silent corticotrophic adenomas vs hormone-negative adenomas. Neurosurgery. 2013 Jul; 73(1):8-17; discussion 17-8.
  13. Englot DJ, Rolston JD, Wang DD, Sun PP, Chang EF, Auguste KI. Seizure outcomes after temporal lobectomy in pediatric patients. J Neurosurg Pediatr. 2013 Aug; 12(2):134-41.
  14. Englot DJ, Breshears JD, Sun PP, Chang EF, Auguste KI. Seizure outcomes after resective surgery for extra-temporal lobe epilepsy in pediatric patients. J Neurosurg Pediatr. 2013 Aug; 12(2):126-33.
  15. Englot DJ, Rutkowski MJ, Ivan ME, Sun PP, Kuperman RA, Chang EF, Gupta N, Sullivan JE, Auguste KI. Effects of temporal lobectomy on consciousness-impairing and consciousness-sparing seizures in children. Childs Nerv Syst. 2013 Oct; 29(10):1915-22.
  16. Hensley-Judge H, Quigg M, Barbaro NM, Newman SA, Ward MM, Chang EF, Broshek DK, Lamborn KR, Laxer KD, Garcia P, Heck CN, Kondziolka D, Beach R, Salanova V, Goodman R. Visual field defects after radiosurgery for mesial temporal lobe epilepsy. Epilepsia. 2013 Aug; 54(8):1376-80.
  17. Rowland NC, Breshears J, Chang EF. Neurosurgery and the dawning age of Brain-Machine Interfaces. Surg Neurol Int. 2013; 4(Suppl 1):S11-4.
  18. Bouchard KE, Mesgarani N, Johnson K, Chang EF. Functional organization of human sensorimotor cortex for speech articulation. Nature. 2013 Mar 21; 495(7441):327-32.
  19. Chang EF, Niziolek CA, Knight RT, Nagarajan SS, Houde JF. Human cortical sensorimotor network underlying feedback control of vocal pitch. Proc Natl Acad Sci U S A. 2013 Feb 12; 110(7):2653-8.
  20. Wang DD, Deans AE, Barkovich AJ, Tihan T, Barbaro NM, Garcia PA, Chang EF. Transmantle sign in focal cortical dysplasia: a unique radiological entity with excellent prognosis for seizure control. J Neurosurg. 2013 Feb; 118(2):337-44.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.