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Edward Chang, M.D.

Neurosurgeon

Dr. Edward Chang is a neurosurgeon with expertise in treating intractable epilepsy, trigeminal neuralgia, movement disorders and brain tumors in adults. He specializes in advanced brain mapping methods, including awake speech and motor mapping, to safely perform surgery in the brain. He also has extensive experience with implantable devices for neuromodulation.

Chang's research focuses upon the brain mechanisms for human speech, movement and cognition. He is faculty in the Center for Integrative Neuroscience and the Neuroscience and Bioengineering graduate programs. He co-directs the Center for Neural Engineering & Prostheses at UC Berkeley and UCSF, which brings together engineering, neuroscience, neurology and neurosurgery to develop state-of-the-art biomedical devices to restore function for patients with neurological disabilities such as paralysis and speech disorders. He earned a medical degree and completed neurosurgery residency training at UCSF. Chang is an associate professor of neurological surgery and physiology at UCSF.

Read a Q&A with Chang about surgical treatments for epilepsy.

Clinics

Epilepsy Center
400 Parnassus Ave., Eighth Floor
San Francisco, CA 94143
Phone: (415) 353-2437
Fax: (415) 353-2837

Hours: Monday to Friday
8 a.m. – 5 p.m.

Neurosurgery Clinic
400 Parnassus Ave., Eighth Floor
San Francisco, CA 94143
Phone: (415) 353-7500
Fax: (415) 353-2889

Hours: Monday to Friday
8 a.m. – 4:30 p.m.

Trigeminal Neuralgia Clinic
400 Parnassus Ave., Eighth Floor
San Francisco, CA 94143
Medical Management:
(415) 353-2892
Surgical Management:
(415) 353-2241
Medical Management Fax:
(415) 353-2898
Surgical Management Fax :
(415) 353-2889

Hours: Monday to Friday
8 a.m. – 5 p.m.

Conditions & Treatments

  • Gamma Knife
  • Glossopharyngeal Neuralgia
  • Hemifacial Spasm

More about Edward Chang

Education

UCSF School of Medicine 2004

Residencies

UCSF Medical Center, Neurosurgery 2010

Selected Research and Publications

  1. Wang DD, Benkli B, Auguste KI, Garcia PA, Sullivan J, Barkovich AJ, Chang EF, Tihan T. Unilateral holohemispheric central nervous system lesions associated with medically refractory epilepsy in the pediatric population: a retrospective series of hemimegalencephaly and Rasmussen's encephalitis. J Neurosurg Pediatr. 2014 Oct 10; 1-12.
  2. Bouchard KE, Chang EF. Control of spoken vowel acoustics and the influence of phonetic context in human speech sensorimotor cortex. J Neurosci. 2014 Sep 17; 34(38):12662-77.
  3. Englot DJ, Raygor KP, Molinaro AM, Garcia PA, Knowlton RC, Auguste KI, Chang EF. Factors Associated With Failed Focal Neocortical Epilepsy Surgery. Neurosurgery. 2014 Aug 29.
  4. Englot DJ, Han SJ, Rolston JD, Ivan ME, Kuperman RA, Chang EF, Gupta N, Sullivan JE, Auguste KI. Epilepsy surgery failure in children: a quantitative and qualitative analysis. J Neurosurg Pediatr. 2014 Oct; 14(4):386-95.
  5. Yu JP, Wilson DM, Chang EF, Cotter J, Perry A, Mahindra A, Glastonbury CM. Isolated intracerebral light chain deposition disease: novel imaging and pathologic findings. Clin Imaging. 2014 Jul 2.
  6. Leonard MK, Chang EF. Dynamic speech representations in the human temporal lobe. Trends Cogn Sci. 2014 Sep; 18(9):472-9.
  7. Cheng JS, Lim DA, Chang EF, Barbaro NM. A review of percutaneous treatments for trigeminal neuralgia. Neurosurgery. 2014 Mar; 10 Suppl 1:25-33.
  8. Dürschmid S, Quandt F, Krämer UM, Hinrichs H, Heinze HJ, Schulz R, Pannek H, Chang EF, Knight RT. Oscillatory dynamics track motor performance improvement in human cortex. PLoS One. 2014; 9(2):e89576.
  9. Englot DJ, Chang EF. Rates and predictors of seizure freedom in resective epilepsy surgery: an update. Neurosurg Rev. 2014 Jul; 37(3):389-405.
  10. Mesgarani N, Cheung C, Johnson K, Chang EF. Phonetic feature encoding in human superior temporal gyrus. Science. 2014 Feb 28; 343(6174):1006-10.
  11. Englot DJ, Lee AT, Tsai C, Halabi C, Barbaro NM, Auguste KI, Garcia PA, Chang EF. Seizure types and frequency in patients who "fail" temporal lobectomy for intractable epilepsy. Neurosurgery. 2013 Nov; 73(5):838-44; quiz 844.
  12. Tate MC, Guo L, McEvoy J, Chang EF. Safety and efficacy of motor mapping utilizing short pulse train direct cortical stimulation. Stereotact Funct Neurosurg. 2013; 91(6):379-85.
  13. Wissel T, Pfeiffer T, Frysch R, Knight RT, Chang EF, Hinrichs H, Rieger JW, Rose G. Hidden Markov model and support vector machine based decoding of finger movements using electrocorticography. J Neural Eng. 2013 Oct; 10(5):056020.
  14. Edwards E, Chang EF. Syllabic (~2-5 Hz) and fluctuation (~1-10 Hz) ranges in speech and auditory processing. Hear Res. 2013 Nov; 305:113-34.
  15. Conant D, Bouchard KE, Chang EF. Speech map in the human ventral sensory-motor cortex. Curr Opin Neurobiol. 2014 Feb; 24(1):63-7.
  16. Burneo JG, Sirven JI, Kiesel LW, Vecht CJ, Jehi L, Chung SS, Uhm J, Politsky JM, Chang EF, Husain AM, Tatum WO, Meador KJ, Noe K, Hesdorffer DC, Herman ST, Wiebe S, Engel J, Schrader S, Parko KL, Dichter MA, Kwan P, Kossoff E, Sperling MR. Managing common complex symptomatic epilepsies: tumors and trauma: american epilepsy society - 2012 annual course summary. Epilepsy Curr. 2013 Sep; 13(5):232-5.
  17. Wang DD, Ouyang D, Englot DJ, Rolston JD, Molinaro AM, Ward M, Chang EF. Trends in surgical treatment for trigeminal neuralgia in the United States of America from 1988 to 2008. J Clin Neurosci. 2013 Nov; 20(11):1538-45.
  18. Jahangiri A, Wagner JR, Pekmezci M, Hiniker A, Chang EF, Kunwar S, Blevins L, Aghi MK. A comprehensive long-term retrospective analysis of silent corticotrophic adenomas vs hormone-negative adenomas. Neurosurgery. 2013 Jul; 73(1):8-17; discussion 17-8.
  19. Englot DJ, Rolston JD, Wang DD, Sun PP, Chang EF, Auguste KI. Seizure outcomes after temporal lobectomy in pediatric patients. J Neurosurg Pediatr. 2013 Aug; 12(2):134-41.
  20. Englot DJ, Breshears JD, Sun PP, Chang EF, Auguste KI. Seizure outcomes after resective surgery for extra-temporal lobe epilepsy in pediatric patients. J Neurosurg Pediatr. 2013 Aug; 12(2):126-33.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.