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Edward F. Chang, M.D.

Neurosurgeon

Dr. Edward Chang is a neurosurgeon with expertise in treating intractable epilepsy, movement disorders and brain tumors in adults. He specializes in advanced brain mapping methods, including awake speech and motor mapping, to safely perform surgery in the brain. He also has extensive training in deep brain stimulation for movement disorders and implantable devices for neuromodulation.

In his research, he studies neurophysiological technologies to preserve and restore speech, movement and cognition. He is a member of the Keck Center for Integrative Neuroscience, and has a secondary appointment in the Department of Physiology. He co-directs the Center for Neural Engineering at UCSF and UC Berkeley, which brings together engineering, neuroscience, neurology and neurosurgery to develop devices to restore function for patients with neurological disabilities such as paralysis and speech disorders. He earned a medical degree and completed neurosurgery residency training at UCSF. He has received several national awards and National Institutes of Health grants for his contributions to neurosurgery and neuroscience. Chang is an assistant professor of Neurological Surgery and Physiology at UCSF.

Read a Q&A with Chang about surgical treatments for epilepsy.

Clinics

Epilepsy Center
400 Parnassus Ave., Eighth Floor
San Francisco, CA 94143
Phone: (415) 353-2437
Fax: (415) 353-2837

Hours: Monday to Friday
8 a.m. – 5 p.m.

Neurosurgery Clinic
400 Parnassus Ave., Eighth Floor
San Francisco, CA 94143
Phone: (415) 353-7500
Fax: (415) 353-2939

Hours: Monday to Friday
8 a.m. – 4:30 p.m.

Surgical Movement Disorders Center
1635 Divisadero St., Suite 520
San Francisco, CA 94115
Neurology: (415) 353-2311
Neurosurgery: (415) 353-2071
Fax: (415) 353-9060

Hours: Monday to Friday
8 a.m. – 5 p.m.

Trigeminal Neuralgia Clinic
400 Parnassus Ave., Eighth Floor
San Francisco, CA 94143
Phone: (415) 353-2241
Fax: (415) 353-2889

Hours: Monday to Friday
8 a.m. – 5 p.m.

Conditions & Treatments

More about Edward F. Chang

Education

UCSF School of Medicine 2004

Residencies

UCSF Medical Center, Neurosurgery 2010

Selected Research and Publications

  1. Rowland NC, Breshears J, Chang EF. Neurosurgery and the dawning age of Brain-Machine Interfaces. Surg Neurol Int. 2013; 4(Suppl 1):S11-4.
  2. Bouchard KE, Mesgarani N, Johnson K, Chang EF. Functional organization of human sensorimotor cortex for speech articulation. Nature. 2013 Mar 21; 495(7441):327-32.
  3. Chang EF, Niziolek CA, Knight RT, Nagarajan SS, Houde JF. Human cortical sensorimotor network underlying feedback control of vocal pitch. Proc Natl Acad Sci U S A. 2013 Feb 12; 110(7):2653-8.
  4. Wang DD, Deans AE, Barkovich AJ, Tihan T, Barbaro NM, Garcia PA, Chang EF. Transmantle sign in focal cortical dysplasia: a unique radiological entity with excellent prognosis for seizure control. J Neurosurg. 2013 Feb; 118(2):337-44.
  5. Ritaccio A, Beauchamp M, Bosman C, Brunner P, Chang E, Crone N, Gunduz A, Gupta D, Knight R, Leuthardt E, Litt B, Moran D, Ojemann J, Parvizi J, Ramsey N, Rieger J, Viventi J, Voytek B, Williams J, Schalk G. Proceedings of the third international workshop on advances in electrocorticography. Epilepsy Behav. 2012 Dec; 25(4):605-13.
  6. Englot DJ, Ouyang D, Wang DD, Rolston JD, Garcia PA, Chang EF. Relationship between hospital surgical volume, lobectomy rates, and adverse perioperative events at US epilepsy centers. J Neurosurg. 2013 Jan; 118(1):169-74.
  7. Englot DJ, Rolston JD, Wang DD, Hassnain KH, Gordon CM, Chang EF. Efficacy of vagus nerve stimulation in posttraumatic versus nontraumatic epilepsy. J Neurosurg. 2012 Nov; 117(5):970-7.
  8. Englot DJ, Young WL, Han SJ, McCulloch CE, Chang EF, Lawton MT. Seizure predictors and control after microsurgical resection of supratentorial arteriovenous malformations in 440 patients. Neurosurgery. 2012 Sep; 71(3):572-80; discussion 580.
  9. Cheung C, Chang EF. Real-time, time-frequency mapping of event-related cortical activation. J Neural Eng. 2012 Aug; 9(4):046018.
  10. Southwell DG, Garcia PA, Berger MS, Barbaro NM, Chang EF. Long-term seizure control outcomes after resection of gangliogliomas. Neurosurgery. 2012 Jun; 70(6):1406-13; discussion 1413-4.
  11. Air EL, Ryapolova-Webb E, de Hemptinne C, Ostrem JL, Galifianakis NB, Larson PS, Chang EF, Starr PA. Acute effects of thalamic deep brain stimulation and thalamotomy on sensorimotor cortex local field potentials in essential tremor. Clin Neurophysiol. 2012 Nov; 123(11):2232-8.
  12. Mesgarani N, Chang EF. Selective cortical representation of attended speaker in multi-talker speech perception. Nature. 2012 May 10; 485(7397):233-6.
  13. Englot DJ, Han SJ, Berger MS, Barbaro NM, Chang EF. Extent of surgical resection predicts seizure freedom in low-grade temporal lobe brain tumors. Neurosurgery. 2012 Apr; 70(4):921-8; discussion 928.
  14. Potts MB, Chang EF, Young WL, Lawton MT. Transsylvian-transinsular approaches to the insula and basal ganglia: operative techniques and results with vascular lesions. Neurosurgery. 2012 Apr; 70(4):824-34; discussion 834.
  15. Englot DJ, Berger MS, Chang EF, Garcia PA. Characteristics and treatment of seizures in patients with high-grade glioma: a review. Neurosurg Clin N Am. 2012 Apr; 23(2):227-35, vii-viii.
  16. Englot DJ, Ouyang D, Garcia PA, Barbaro NM, Chang EF. Epilepsy surgery trends in the United States, 1990-2008. Neurology. 2012 Apr 17; 78(16):1200-6.
  17. Rolston JD, Englot DJ, Wang DD, Shih T, Chang EF. Comparison of seizure control outcomes and the safety of vagus nerve, thalamic deep brain, and responsive neurostimulation: evidence from randomized controlled trials. Neurosurg Focus. 2012 Mar; 32(3):E14.
  18. Rowland NC, Englot DJ, Cage TA, Sughrue ME, Barbaro NM, Chang EF. A meta-analysis of predictors of seizure freedom in the surgical management of focal cortical dysplasia. J Neurosurg. 2012 May; 116(5):1035-41.
  19. Englot DJ, Wang DD, Rolston JD, Shih TT, Chang EF. Rates and predictors of long-term seizure freedom after frontal lobe epilepsy surgery: a systematic review and meta-analysis. J Neurosurg. 2012 May; 116(5):1042-8.
  20. Pasley BN, David SV, Mesgarani N, Flinker A, Shamma SA, Crone NE, Knight RT, Chang EF. Reconstructing speech from human auditory cortex. PLoS Biol. 2012 Jan; 10(1):e1001251.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions by logging on to UCSF Profiles.

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