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Farid Chehab, Ph.D.

Laboratory medicine specialist

Education


Selected Research and Publications

  1. Habbal MZ, Bou-Assi T, Zhu J, Owen R, Chehab FF. First report of a deletion encompassing an entire exon in the homogentisate 1,2-dioxygenase gene causing alkaptonuria. PLoS One. 2014; 9(9):e106948.
  2. Zhu J, Jiang X, Chehab FF. FoxO4 interacts with the sterol regulatory factor SREBP2 and the hypoxia inducible factor HIF2a at the CYP51 promoter. J Lipid Res. 2014 Mar; 55(3):431-42.
  3. Zhu J, Qiu J, Magrane G, Abedalthagafi M, Zanko A, Golabi M, Chehab FF. Duplication of C7orf58, WNT16 and FAM3C in an obese female with a t(7;22)(q32.1;q11.2) chromosomal translocation and clinical features resembling Coffin-Siris Syndrome. PLoS One. 2012; 7(12):e52353.
  4. Van Ziffle J, Yang W, Chehab FF. Homozygous deletion of six olfactory receptor genes in a subset of individuals with Beta-thalassemia. PLoS One. 2011; 6(2):e17327.
  5. Zhu J, Mounzih K, Chehab EF, Mitro N, Saez E, Chehab FF. Effects of FoxO4 overexpression on cholesterol biosynthesis, triacylglycerol accumulation, and glucose uptake. J Lipid Res. 2010 Jun; 51(6):1312-24.
  6. Wang B, Zhu J, Mounzih K, Chehab EF, Ke Y, Chehab FF. Overexpression of the transcription factor Foxo4 is associated with rapid glucose clearance. Mol Cell Endocrinol. 2009 Aug 13; 307(1-2):217-23.
  7. Chehab FF. Obesity and lipodystrophy--where do the circles intersect? Endocrinology. 2008 Mar; 149(3):925-34.
  8. Wang B, Chehab FF. Deletion of the serotonin 2c receptor from transgenic mice overexpressing leptin does not affect their lipodystrophy but exacerbates their diet-induced obesity. Biochem Biophys Res Commun. 2006 Dec 15; 351(2):418-23.
  9. Han XD, Powell BR, Phalin JL, Chehab FF. Mosaicism for a full mutation, premutation, and deletion of the CGG repeats results in 22% FMRP and elevated FMR1 mRNA levels in a high-functioning fragile X male. Am J Med Genet A. 2006 Jul 1; 140(13):1463-71.
  10. Chehab FF, Qiu J, Ogus S. The use of animal models to dissect the biology of leptin. Recent Prog Horm Res. 2004; 59:245-66.
  11. Ke Y, Qiu J, Ogus S, Shen WJ, Kraemer FB, Chehab FF. Overexpression of leptin in transgenic mice leads to decreased basal lipolysis, PKA activity, and perilipin levels. Biochem Biophys Res Commun. 2003 Dec 26; 312(4):1165-70.
  12. Ogus S, Ke Y, Qiu J, Wang B, Chehab FF. Hyperleptinemia precipitates diet-induced obesity in transgenic mice overexpressing leptin. Endocrinology. 2003 Jul; 144(7):2865-9.
  13. Chehab FF, Qiu J, Mounzih K, Ewart-Toland A, Ogus S. Leptin and reproduction. Nutr Rev. 2002 Oct; 60(10 Pt 2):S39-46; discussion S68-84, 85-7.
  14. Qiu J, Ogus S, Mounzih K, Ewart-Toland A, Chehab FF. Leptin-deficient mice backcrossed to the BALB/cJ genetic background have reduced adiposity, enhanced fertility, normal body temperature, and severe diabetes. Endocrinology. 2001 Aug; 142(8):3421-5.
  15. Qiu J, Ogus S, Lu R, Chehab FF. Transgenic mice overexpressing leptin accumulate adipose mass at an older, but not younger, age. Endocrinology. 2001 Jan; 142(1):348-58.
  16. Chehab FF. Leptin as a regulator of adipose mass and reproduction. Trends Pharmacol Sci. 2000 Aug; 21(8):309-14.
  17. Ewart-Toland A, Mounzih K, Qiu J, Chehab FF. Effect of the genetic background on the reproduction of leptin-deficient obese mice. Endocrinology. 1999 Feb; 140(2):732-8.
  18. Mounzih K, Qiu J, Ewart-Toland A, Chehab FF. Leptin is not necessary for gestation and parturition but regulates maternal nutrition via a leptin resistance state. Endocrinology. 1998 Dec; 139(12):5259-62.
  19. Chehab F, Khaiz D, Lakhloufi A, Bouzidi A. [Ovarian teratoma prolapsed into the rectum]. Ann Chir. 1998; 52(1):101.
  20. Vuillaumier S, Dixmeras I, Messa√Į H, Lapoum√©roulie C, Lallemand D, Gekas J, Chehab FF, Perret C, Elion J, Denamur E. Cross-species characterization of the promoter region of the cystic fibrosis transmembrane conductance regulator gene reveals multiple levels of regulation. Biochem J. 1997 Nov 1; 327 ( Pt 3):651-62.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.