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Geoffrey T. Manley, M.D., Ph.D.

Neurosurgeon

Dr. Geoffrey T. Manley, a trauma neurosurgeon and an internationally recognized expert in neurotrauma, specializes in brain and spinal cord injury and neurocritical care. He is a leader in the rapidly growing field of advanced neuromonitoring and clinical informatics for critical care.

Manley is a graduate of the Medical Scientist Training Program at Cornell University Medical College, where he earned a medical degree and doctorate in neuroscience. He completed a residency in neurosurgery and a postdoctoral fellowship in molecular biophysics at UCSF. Manley is a member of the California Institute for Quantitative Biosciences and the UCSF Center for Clinical and Translational Informatics. He has published over 120 manuscripts that reflect a wide range of research interests from molecular aspects of brain injury to the clinical care of head trauma patients. He has helped to define new molecular mechanisms of injury to the nervous system that may lead to new treatments for these devastating injuries. His many honors include the General Motors Trauma Research Award and Trauma Research Award from the American College of Surgeons. He has served as a consultant for the Prehospital Guidelines Committee for the World Health Organization and on a number of committees for the National Institutes of Health. He is chief of Neurosurgery at San Francisco General Hospital and a professor of neurosurgery at UCSF.

Clinics

Concussion and Brain Injury Program
1500 Owens St., Second Floor
San Francisco, CA 94158
Phone: (415) 353-1915
Fax: (415) 514-6075

Hours: Monday to Friday
8 a.m. – 5 p.m.

More about Geoffrey T. Manley

Education

Cornell University Medical College 1995

Residencies

UCSF Medical Center 2001

Selected Research and Publications

  1. Yuh EL, Mukherjee P, Lingsma HF, Yue JK, Ferguson AR, Gordon WA, Valadka AB, Schnyer DM, Okonkwo DO, Maas AI, Manley GT. Magnetic resonance imaging improves 3-month outcome prediction in mild traumatic brain injury. Ann Neurol. 2013 Feb; 73(2):224-35.
  2. Rosenfeld JV, Maas AI, Bragge P, Morganti-Kossmann MC, Manley GT, Gruen RL. Early management of severe traumatic brain injury. Lancet. 2012 Sep 22; 380(9847):1088-98.
  3. Moen KG, Skandsen T, Folvik M, Brezova V, Kvistad KA, Rydland J, Manley GT, Vik A. A longitudinal MRI study of traumatic axonal injury in patients with moderate and severe traumatic brain injury. J Neurol Neurosurg Psychiatry. 2012 Dec; 83(12):1193-200.
  4. Laroche M, Kutcher ME, Huang MC, Cohen MJ, Manley GT. Coagulopathy after traumatic brain injury. Neurosurgery. 2012 Jun; 70(6):1334-45.
  5. Yuh EL, Cooper SR, Ferguson AR, Manley GT. Quantitative CT improves outcome prediction in acute traumatic brain injury. J Neurotrauma. 2012 Mar 20; 29(5):735-46.
  6. Maas AI, Menon DK, Lingsma HF, Pineda JA, Sandel ME, Manley GT. Re-orientation of clinical research in traumatic brain injury: report of an international workshop on comparative effectiveness research. J Neurotrauma. 2012 Jan 1; 29(1):32-46.
  7. Nakagawa K, Hills NK, Kamel H. The effect of decompressive hemicraniectomy on brain temperature after severe brain injury. Neurocrit Care. 2011 Aug; 15(1):101-6.
  8. Sughrue ME, Bloch OG, Manley GT, Stiver SI. Marked reduction in wound complication rates following decompressive hemicraniectomy with an improved operative closure technique. J Clin Neurosci. 2011 Sep; 18(9):1201-5.
  9. Flint AC, Gean AD, Manley GT, Rao VA, Sheridan WF, von Koch CS. Temporizing treatment of hyperacute subdural hemorrhage by subdural evacuation port system placement. J Neurosurg. 2011 Oct; 115(4):844-8.
  10. Nakagawa A, Manley GT, Gean AD, Ohtani K, Armonda R, Tsukamoto A, Yamamoto H, Takayama K, Tominaga T. Mechanisms of primary blast-induced traumatic brain injury: insights from shock-wave research. J Neurotrauma. 2011 Jun; 28(6):1101-19.
  11. Beattie MS, Manley GT. Tight squeeze, slow burn: inflammation and the aetiology of cervical myelopathy. Brain. 2011 May; 134(Pt 5):1259-61.
  12. Sorani MD, Manley GT, Claude Hemphill J, Baranzini SE. Dynamic, multi-level network models of clinical trials. Pac Symp Biocomput. 2011; 38-49.
  13. Manley GT, Diaz-Arrastia R, Brophy M, Engel D, Goodman C, Gwinn K, Veenstra TD, Ling G, Ottens AK, Tortella F, Hayes RL. Common data elements for traumatic brain injury: recommendations from the biospecimens and biomarkers working group. Arch Phys Med Rehabil. 2010 Nov; 91(11):1667-72.
  14. Voytek B, Secundo L, Bidet-Caulet A, Scabini D, Stiver SI, Gean AD, Manley GT, Knight RT. Hemicraniectomy: a new model for human electrophysiology with high spatio-temporal resolution. J Cogn Neurosci. 2010 Nov; 22(11):2491-502.
  15. Whyte J, Vasterling J, Manley GT. Common data elements for research on traumatic brain injury and psychological health: current status and future development. Arch Phys Med Rehabil. 2010 Nov; 91(11):1692-6.
  16. Monson KL, Matsumoto MM, Young WL, Manley GT, Hashimoto T. Abrupt increase in rat carotid blood flow induces rapid alteration of artery mechanical properties. J Mech Behav Biomed Mater. 2011 Jan; 4(1):9-15.
  17. Gean AD, Fischbein NJ, Purcell DD, Aiken AH, Manley GT, Stiver SI. Benign anterior temporal epidural hematoma: indolent lesion with a characteristic CT imaging appearance after blunt head trauma. Radiology. 2010 Oct; 257(1):212-8.
  18. Rosenthal G, Sanchez-Mejia RO, Phan N, Hemphill JC, Martin C, Manley GT. Incorporating a parenchymal thermal diffusion cerebral blood flow probe in bedside assessment of cerebral autoregulation and vasoreactivity in patients with severe traumatic brain injury. J Neurosurg. 2011 Jan; 114(1):62-70.
  19. Cohen MJ, Grossman AD, Morabito D, Knudson MM, Butte AJ, Manley GT. Identification of complex metabolic states in critically injured patients using bioinformatic cluster analysis. Crit Care. 2010; 14(1):R10.
  20. Chun KA, Manley GT, Stiver SI, Aiken AH, Phan N, Wang V, Meeker M, Cheng SC, Gean AD, Wintermark M. Interobserver variability in the assessment of CT imaging features of traumatic brain injury. J Neurotrauma. 2010 Feb; 27(2):325-30.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions by logging on to UCSF Profiles.