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Homer Boushey, M.D.

Chief of Allergy and Immunology

Dr. Homer Boushey is recognized nationally and internationally for his work in the field of pulmonary medicine. He is an expert in clinical research on diseases of the airways, such as asthma and chronic obstructive pulmonary disease (COPD) and has focused on the effects of pollutants, allergens and infectious agents. He has studied the causes and treatments of asthma for over 30 years, and has lately focused on applying new methods for detecting microbes to the study not only of asthma, but also of COPD, pulmonary fibrosis, and other lung diseases.

Boushey received his medical degree from the UCSF in 1968, completed residency training in internal medicine at UCSF and at the Beth-Israel Hospital of Harvard Medical School, and pursued specialty training in pulmonary medicine at Oxford University and UCSF. He joined the UCSF faculty in 1974, serving as vice-chair of the Department of Medicine and Chief of the Medical Service from 1989-1995, and recently as chief of the Division of Allergy and Immunology and director of the Asthma Clinical Research Center.

Clinics

Allergy and Immunology
400 Parnassus Ave., Fifth Floor
San Francisco, CA 94143
Phone: (415) 353-2725
Fax: (415) 353-2568

Hours: Monday to Friday
8 a.m. – 5 p.m.

Asthma Clinic
400 Parnassus Ave., Fifth Floor
San Francisco, CA 94143-0359
Phone: (415) 353-2961

Hours: Thursdays
8:30 – 11:30 a.m.

Pulmonary Practice at Parnassus
400 Parnassus Ave., Fifth Floor
San Francisco, CA 94143-0359
Phone: (415) 353-2961
Fax: (415) 353-2568

Hours: Monday to Friday
8 a.m. – 5 p.m.

Conditions & Treatments

More about Homer Boushey

Additional Languages

French

Education

UCSF 1968

Residencies

UCSF, Internal Medicine 1970

Fellowships

UCSF, Pulmonary Diseases 1973

Selected Research and Publications

  1. Lynch SV, Wood RA, Boushey H, Bacharier LB, Bloomberg GR, Kattan M, O'Connor GT, Sandel MT, Calatroni A, Matsui E, Johnson CC, Lynn H, Visness CM, Jaffee KF, Gergen PJ, Gold DR, Wright RJ, Fujimura K, Rauch M, Busse WW, Gern JE. Effects of early-life exposure to allergens and bacteria onĀ recurrent wheeze and atopy in urban children. J Allergy Clin Immunol. 2014 Sep; 134(3):593-601.e12.
  2. Castro M, King TS, Kunselman SJ, Cabana MD, Denlinger L, Holguin F, Kazani SD, Moore WC, Moy J, Sorkness CA, Avila P, Bacharier LB, Bleecker E, Boushey HA, Chmiel J, Fitzpatrick AM, Gentile D, Hundal M, Israel E, Kraft M, Krishnan JA, LaForce C, Lazarus SC, Lemanske R, Lugogo N, Martin RJ, Mauger DT, Naureckas E, Peters SP, Phipatanakul W, Que LG, Sheshadri A, Smith L, Solway J, Sullivan-Vedder L, Sumino K, Wechsler ME, Wenzel S, White SR, Sutherland ER. Effect of vitamin D3 on asthma treatment failures in adults with symptomatic asthma and lower vitamin D levels: the VIDA randomized clinical trial. JAMA. 2014 May 28; 311(20):2083-91.
  3. Huang YJ, Sethi S, Murphy T, Nariya S, Boushey HA, Lynch SV. Airway microbiome dynamics in exacerbations of chronic obstructive pulmonary disease. J Clin Microbiol. 2014 Aug; 52(8):2813-23.
  4. McErlean P, Berdnikovs S, Favoreto S, Shen J, Biyasheva A, Barbeau R, Eisley C, Barczak A, Ward T, Schleimer RP, Erle DJ, Boushey HA, Avila PC. Asthmatics with exacerbation during acute respiratory illness exhibit unique transcriptional signatures within the nasal mucosa. Genome Med. 2014; 6(1):1.
  5. Huang YJ, Boushey HA. The microbiome and asthma. Ann Am Thorac Soc. 2014 Jan; 11 Suppl 1:S48-51.
  6. Cho SH, Hong SJ, Chen H, Habib A, Cho D, Lee SH, Kang J, Ward T, Boushey HA, Schleimer RP, Avila PC. Plasminogen activator inhibitor-1 in sputum and nasal lavage fluids increases in asthmatic patients during common colds. J Allergy Clin Immunol. 2014 May; 133(5):1465-1467.e2.
  7. Fujimura KE, Demoor T, Rauch M, Faruqi AA, Jang S, Johnson CC, Boushey HA, Zoratti E, Ownby D, Lukacs NW, Lynch SV. House dust exposure mediates gut microbiome Lactobacillus enrichment and airway immune defense against allergens and virus infection. Proc Natl Acad Sci U S A. 2014 Jan 14; 111(2):805-10.
  8. Huang YJ, Boushey HA. The bronchial microbiome and asthma phenotypes. Am J Respir Crit Care Med. 2013 Nov 15; 188(10):1178-80.
  9. Rom WN, Boushey H, Caplan A. Experimental human exposure to air pollutants is essential to understand adverse health effects. Am J Respir Cell Mol Biol. 2013 Nov; 49(5):691-6.
  10. Peters SP, Bleecker ER, Kunselman SJ, Icitovic N, Moore WC, Pascual R, Ameredes BT, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Craig T, Denlinger LC, Engle LL, Dimango EA, Israel E, Kraft M, Lazarus SC, Lemanske RF, Lugogo N, Martin RJ, Meyers DA, Ramsdell J, Sorkness CA, Sutherland ER, Wasserman SI, Walter MJ, Wechsler ME, Chinchilli VM, Szefler SJ. Predictors of response to tiotropium versus salmeterol in asthmatic adults. J Allergy Clin Immunol. 2013 Nov; 132(5):1068-1074.e1.
  11. Himes BE, Qiu W, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Nieuwenhuis MA, Postma DS, Vonk JM, Rafaels N, Hansel NN, Barnes K, Raby B, Tantisira KG, Weiss ST. ITGB5 and AGFG1 variants are associated with severity of airway responsiveness. BMC Med Genet. 2013; 14:86.
  12. Li X, Hawkins GA, Ampleford EJ, Moore WC, Li H, Hastie AT, Howard TD, Boushey HA, Busse WW, Calhoun WJ, Castro M, Erzurum SC, Israel E, Lemanske RF, Szefler SJ, Wasserman SI, Wenzel SE, Peters SP, Meyers DA, Bleecker ER. Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients. J Allergy Clin Immunol. 2013 Aug; 132(2):313-20.e15.
  13. Himes BE, Sheppard K, Berndt A, Leme AS, Myers RA, Gignoux CR, Levin AM, Gauderman WJ, Yang JJ, Mathias RA, Romieu I, Torgerson DG, Roth LA, Huntsman S, Eng C, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Postma DS, Nieuwenhuis MA, Vonk JM, Lima JJ, Irvin CG, Peters SP, Kubo M, Tamari M, Nakamura Y, Litonjua AA, Tantisira KG, Raby BA, Bleecker ER, Meyers DA, London SJ, Barnes KC, Gilliland FD, Williams LK, Burchard EG, Nicolae DL, Ober C, DeMeo DL, Silverman EK, Paigen B, Churchill G, Shapiro SD, Weiss ST. Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene. PLoS One. 2013; 8(2):e56179.
  14. Calhoun WJ, Boushey HA, Ameredes BT. Strategies for tailoring asthma treatment in adults--reply. JAMA. 2013 Jan 9; 309(2):136-7.
  15. Denlinger LC, Manthei DM, Seibold MA, Ahn K, Bleecker E, Boushey HA, Calhoun WJ, Castro M, Chinchili VM, Fahy JV, Hawkins GA, Icitovic N, Israel E, Jarjour NN, King T, Kraft M, Lazarus SC, Lehman E, Martin RJ, Meyers DA, Peters SP, Sheerar D, Shi L, Sutherland ER, Szefler SJ, Wechsler ME, Sorkness CA, Lemanske RF. P2X7-regulated protection from exacerbations and loss of control is independent of asthma maintenance therapy. Am J Respir Crit Care Med. 2013 Jan 1; 187(1):28-33.
  16. Calhoun WJ, Ameredes BT, King TS, Icitovic N, Bleecker ER, Castro M, Cherniack RM, Chinchilli VM, Craig T, Denlinger L, DiMango EA, Engle LL, Fahy JV, Grant JA, Israel E, Jarjour N, Kazani SD, Kraft M, Kunselman SJ, Lazarus SC, Lemanske RF, Lugogo N, Martin RJ, Meyers DA, Moore WC, Pascual R, Peters SP, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Wasserman SI, Walter MJ, Wechsler ME, Boushey HA. Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: the BASALT randomized controlled trial. JAMA. 2012 Sep 12; 308(10):987-97.
  17. Fujimura KE, Rauch M, Matsui E, Iwai S, Calatroni A, Lynn H, Mitchell H, Johnson CC, Gern JE, Togias A, Boushey HA, Kennedy S, Lynch SV. Development of a standardized approach for environmental microbiota investigations related to asthma development in children. J Microbiol Methods. 2012 Nov; 91(2):231-9.
  18. Alton EW, Boushey HA, Garn H, Green FH, Hodges M, Martin RJ, Murdoch RD, Renz H, Shrewsbury SB, Seguin R, Johnson G, Parry JD, Tepper J, Renzi P, Cavagnaro J, Ferrari N. Clinical expert panel on monitoring potential lung toxicity of inhaled oligonucleotides: consensus points and recommendations. Nucleic Acid Ther. 2012 Aug; 22(4):246-54.
  19. Wegienka G, Hasiec E, Boushey H, Johnson CC, Strickler R, Zoratti E, Havstad S. Studying forced expiratory volume at 1?second over menstrual segments in asthmatic and non-asthmatic women: assessing protocol feasibility. BMC Res Notes. 2012; 5:261.
  20. Kumar R, Williams LK, Kato A, Peterson EL, Favoreto S, Hulse K, Wang D, Beckman K, Thyne S, LeNoir M, Meade K, Lanfear DE, Levin AM, Favro D, Yang JJ, Weiss K, Boushey HA, Grammer L, Avila PC, Burchard EG, Schleimer R. Genetic variation in B cell-activating factor of the TNF family (BAFF) and asthma exacerbations among African American subjects. J Allergy Clin Immunol. 2012 Oct; 130(4):996-9.e6.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.