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James Smith, M.D., M.S.

Director, UCSF Male Reproductive Health

Dr. James Smith directs the team providing male fertility preservation counseling and treatment, and evaluates and treats men with general fertility problems, low testosterone, erectile dysfunction and Peyronie's disease. He specializes in the use of microsurgical vasovasostomy, vasoepididymostomy, sperm retrieval and varicocelectomy. In addition to serving as director of Male Reproductive Health, Smith is an assistant professor of urology and of obstetrics, gynecology and reproductive sciences at the UCSF School of Medicine.

Smith's primary research focus seeks to improve understanding of clinical, translational and basic mechanisms of male reproductive biology. Smith is an active member of the American Urological Association, the American Society for Reproductive Medicine, the Society of Reproductive Surgeons, the Society for Male Reproduction and Urology, and the Sexual Medicine Society of North America.

Smith received his master's degree in health and medical science, and his medical degree, from the University of California's Joint Medical Program (UC Berkeley and UCSF). He did his general surgery and urology training at the University of Utah in Salt Lake City, returning to UCSF to complete a fellowship in andrology.

Clinics

Center for Reproductive Health
2356 Sutter St., Seventh Floor
San Francisco, CA 94115
Phone: (415) 353-7475
Fax: (415) 353-7744

Hours: Monday to Friday
8 a.m. – 4:45 p.m.
Saturday and Sunday apts. available for patients undergoing treatment

Fertility Preservation Center
2356 Sutter St., Seventh Floor
San Francisco, CA 94115
Phone: (415) 353-9115
Fax: (415) 353-3064

Hours: Monday to Friday
8 a.m. – 5 p.m.

Male Reproductive Health Center
2356 Sutter St., Third Floor
San Francisco, CA 94115
Phone: (415) 353-3076
Fax: (415) 885-3663

Hours: Monday to Friday
8 a.m. – 5 p.m.

Urology Practice
400 Parnassus Ave., Sixth Floor, Suite A610
San Francisco, CA 94143
Phone: (415) 353-2200
Fax: (415) 353-2641

Hours: Monday to Friday
8 a.m. – 5 p.m.

Conditions & Treatments

More about James Smith

Education

UCSF School of Medicine 2002

Residencies

University of Utah, Surgery and Urology 2007

Fellowships

UCSF Medical Center, Male Reproductive Health 2009

Selected Research and Publications

  1. Carter KA, Smith JF, White MM, Serpe MD. Assessing the diversity of arbuscular mycorrhizal fungi in semiarid shrublands dominated by Artemisia tridentata ssp. wyomingensis. Mycorrhiza. 2014 May; 24(4):301-14.
  2. Mannowetz N, Naidoo NM, Choo SA, Smith JF, Lishko PV. Slo1 is the principal potassium channel of human spermatozoa. Elife. 2013; 2:e01009.
  3. Gaskin JF, Schwarzländer M, Kinter CL, Smith JF, Novak SJ. Propagule pressure, genetic structure, and geographic origins of Chondrilla juncea (Asteraceae): an apomictic invader on three continents. Am J Bot. 2013 Sep; 100(9):1871-82.
  4. Wu AK, Odisho AY, Washington SL, Katz PP, Smith JF. Out-of-Pocket Fertility Patient Expense: Data from a Multicenter Prospective Infertility Cohort. J Urol. 2014 Feb; 191(2):427-32.
  5. Smith JF, Syritsyna O, Fellous M, Serres C, Mannowetz N, Kirichok Y, Lishko PV. Disruption of the principal, progesterone-activated sperm Ca2+ channel in a CatSper2-deficient infertile patient. Proc Natl Acad Sci U S A. 2013 Apr 23; 110(17):6823-8.
  6. Mitton-Fry MJ, Brickner SJ, Hamel JC, Brennan L, Casavant JM, Chen M, Chen T, Ding X, Driscoll J, Hardink J, Hoang T, Hua E, Huband MD, Maloney M, Marfat A, McCurdy SP, McLeod D, Plotkin M, Reilly U, Robinson S, Schafer J, Shepard RM, Smith JF, Stone GG, Subramanyam C, Yoon K, Yuan W, Zaniewski RP, Zook C. Novel quinoline derivatives as inhibitors of bacterial DNA gyrase and topoisomerase IV. Bioorg Med Chem Lett. 2013 May 15; 23(10):2955-61.
  7. Wu AK, Elliott P, Katz PP, Smith JF. Time costs of fertility care: the hidden hardship of building a family. Fertil Steril. 2013 Jun; 99(7):2025-30.
  8. Clay DL, Novak SJ, Serpe MD, Tank DC, Smith JF. Homoploid hybrid speciation in a rare endemic Castilleja from Idaho (Castilleja christii, Orobanchaceae). Am J Bot. 2012 Dec; 99(12):1976-90.
  9. Letourneau JM, Smith JF, Ebbel EE, Craig A, Katz PP, Cedars MI, Rosen MP. Racial, socioeconomic, and demographic disparities in access to fertility preservation in young women diagnosed with cancer. Cancer. 2012 Sep 15; 118(18):4579-88.
  10. Smith JF, Breyer BN, Shindel AW. Predictors of sexual bother in a population of male North American medical students. J Sex Med. 2011 Dec; 8(12):3363-9.
  11. Nangia AK, Luke B, Smith JF, Mak W, Stern JE. National study of factors influencing assisted reproductive technology outcomes with male factor infertility. Fertil Steril. 2011 Sep; 96(3):609-14.
  12. Weiss DA, Harris CR, Smith JF. The use of complementary and alternative fertility treatments. Curr Opin Obstet Gynecol. 2011 Jun; 23(3):195-9.
  13. Smith JF, Eisenberg ML, Glidden D, Millstein SG, Cedars M, Walsh TJ, Showstack J, Pasch LA, Adler N, Katz PP. Socioeconomic disparities in the use and success of fertility treatments: analysis of data from a prospective cohort in the United States. Fertil Steril. 2011 Jul; 96(1):95-101.
  14. Shindel AW, Horberg MA, Smith JF, Breyer BN. Sexual dysfunction, HIV, and AIDS in men who have sex with men. AIDS Patient Care STDS. 2011 Jun; 25(6):341-9.
  15. Breyer BN, Van den Eeden SK, Horberg MA, Eisenberg ML, Deng DY, Smith JF, Shindel AW. HIV status is an independent risk factor for reporting lower urinary tract symptoms. J Urol. 2011 May; 185(5):1710-5.
  16. Katz P, Showstack J, Smith JF, Nachtigall RD, Millstein SG, Wing H, Eisenberg ML, Pasch LA, Croughan MS, Adler N. Costs of infertility treatment: results from an 18-month prospective cohort study. Fertil Steril. 2011 Mar 1; 95(3):915-21.
  17. Smith JF, Shindel AW, Huang YC, Clavijo RI, Flechner L, Breyer BN, Eisenberg ML, Lue TF. Pentoxifylline treatment and penile calcifications in men with Peyronie's disease. Asian J Androl. 2011 Mar; 13(2):322-5.
  18. Rowen TS, Smith JF, Eisenberg ML, Breyer BN, Drey EA, Shindel AW. Contraceptive usage patterns in North American medical students. Contraception. 2011 May; 83(5):459-65.
  19. Smith JF, Breyer BN, Eisenberg ML, Sharlip ID, Shindel AW. Sexual function and depressive symptoms among male North American medical students. J Sex Med. 2010 Dec; 7(12):3909-17.
  20. Shindel AW, Eisenberg ML, Breyer BN, Sharlip ID, Smith JF. Sexual function and depressive symptoms among female North American medical students. J Sex Med. 2011 Feb; 8(2):391-9.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.