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Jeffrey Pearl, M.D.


Dr. Jeffrey M. Pearl is a general surgeon and director of the Hernia Center at UCSF Medical Center at Mount Zion. Pearl specializes in the use of a polypropylene device for hernia repair and is board certified in gastrointestinal surgery. He also is associate chief medical officer for UCSF Medical Center at Mount Zion and associate dean of the UCSF School of Medicine at the Mount Zion campus. As associate chief medical officer, he is responsible for the oversight of physician activities and quality programs at Mount Zion. Pearl earned his medical degree from the Mount Sinai School of Medicine in New York and completed his residency at the University of California, San Diego.

More about Jeffrey Pearl


Mount Sinai School of Medicine 1970


UC San Diego, General Surgery 1976

Selected Research and Publications

  1. Pearl JM, Donaldson NE. Surprise wire. AORN J. 2010 Aug; 92(2):250, 208.
  2. Pearl JM, Plank DM, McLean KM, Wagner CJ, Duffy JY. Glucocorticoids improve calcium cycling in cardiac myocytes after cardiopulmonary bypass. J Surg Res. 2011 May 15; 167(2):279-86.
  3. Anagnostopoulos PV, Pearl JM, Octave C, Cohen M, Gruessner A, Wintering E, Teodori MF. Improved current era outcomes in patients with heterotaxy syndromes. Eur J Cardiothorac Surg. 2009 May; 35(5):871-7; discussion 877-8.
  4. Duffy JY, McLean KM, Lyons JM, Czaikowski AJ, Wagner CJ, Pearl JM. Modulation of nuclear factor-kappaB improves cardiac dysfunction associated with cardiopulmonary bypass and deep hypothermic circulatory arrest. Crit Care Med. 2009 Feb; 37(2):577-83.
  5. Yeung VH, Pearl JM, Coakley FV, Joe BN, Westphalen AC, Yeh BM. Computed tomographic appearance of Prolene Hernia System and polypropylene mesh plug inguinal hernia repair. J Comput Assist Tomogr. 2008 Jul-Aug; 32(4):529-32.
  6. Pandalai PK, McLean KM, Bulcao CF, Duffy JY, D'Souza KM, Merrill WH, Pearl JM, Akhter SA. Acute beta-blockade prevents myocardial beta-adrenergic receptor desensitization and preserves early ventricular function after brain death. J Thorac Cardiovasc Surg. 2008 Apr; 135(4):792-8.
  7. Ashcraft TM, Jones K, Border WL, Eghtesady P, Pearl JM, Khoury PR, Manning PB. Factors affecting long-term risk of aortic arch recoarctation after the Norwood procedure. Ann Thorac Surg. 2008 Apr; 85(4):1397-401; discussion 1401-2.
  8. McKenna DA, Carter JT, Poder L, Gosnell JE, Maa J, Pearl JM, Goldstein RB. Round ligament varices: sonographic appearance in pregnancy. Ultrasound Obstet Gynecol. 2008 Mar; 31(3):355-7.
  9. McLean KM, Pandalai PK, Pearl JM, Bulcao CF, Lyons JM, Wagner CJ, Akhter SA, Duffy JY. Beta-adrenergic receptor antagonism preserves myocardial function after brain death in a porcine model. J Heart Lung Transplant. 2007 May; 26(5):522-8.
  10. Gudausky TM, Pearl J, Dent CL, Kim E, Divanovic A, Spicer RL, Beekman RH. Open-chest epicardial approach to transcatheter pulmonary artery stenting following heart transplantation in an infant. Congenit Heart Dis. 2007 Jan-Feb; 2(1):64-9.
  11. McLean KM, Duffy JY, Pandalai PK, Lyons JM, Bulcao CF, Wagner CJ, Akhter SA, Pearl JM. Glucocorticoids alter the balance between pro- and anti-inflammatory mediators in the myocardium in a porcine model of brain death. J Heart Lung Transplant. 2007 Jan; 26(1):78-84.
  12. McLean KM, Pearl JM. Pulmonary atresia with intact ventricular septum: initial management. Ann Thorac Surg. 2006 Dec; 82(6):2214-9; discussion 2219-20.
  13. McLean KM, Lorts A, Pearl JM. Current treatments for congenital aortic stenosis. Curr Opin Cardiol. 2006 May; 21(3):200-4.
  14. Hinton RB, Deutsch GH, Pearl JM, Hobart HH, Morris CA, Benson DW. Bilateral semilunar valve disease in a child with partial deletion of the Williams-Beuren syndrome region is associated with elastin haploinsufficiency. J Heart Valve Dis. 2006 May; 15(3):352-5.
  15. Dent CL, Spaeth JP, Jones BV, Schwartz SM, Glauser TA, Hallinan B, Pearl JM, Khoury PR, Kurth CD. Brain magnetic resonance imaging abnormalities after the Norwood procedure using regional cerebral perfusion. J Thorac Cardiovasc Surg. 2006 Jan; 131(1):190-7.
  16. Dent CL, Spaeth JP, Jones BV, Schwartz SM, Glauser TA, Hallinan B, Pearl JM, Khoury PR, Kurth CD. Brain magnetic resonance imaging abnormalities after the Norwood procedure using regional cerebral perfusion. J Thorac Cardiovasc Surg. 2005 Dec; 130(6):1523-30.
  17. Lyons JM, Pearl JM, McLean KM, Akhter SA, Wagner CJ, Pandalai PK, Duffy JY. Glucocorticoid administration reduces cardiac dysfunction after brain death in pigs. J Heart Lung Transplant. 2005 Dec; 24(12):2249-54.
  18. Eghtesady P, Nelson D, Schwartz SM, Wheeler D, Pearl JM, Cripe LH, Manning PB. Heparin-induced thrombocytopenia complicating support by the Berlin Heart. ASAIO J. 2005 Nov-Dec; 51(6):820-5.
  19. Pandalai PK, Lyons JM, Duffy JY, McLean KM, Wagner CJ, Merrill WH, Pearl JM, Akhter SA. Role of the beta-adrenergic receptor kinase in myocardial dysfunction after brain death. J Thorac Cardiovasc Surg. 2005 Oct; 130(4):1183-9.
  20. Kaiser RA, Lyons JM, Duffy JY, Wagner CJ, McLean KM, O'Neill TP, Pearl JM, Molkentin JD. Inhibition of p38 reduces myocardial infarction injury in the mouse but not pig after ischemia-reperfusion. Am J Physiol Heart Circ Physiol. 2005 Dec; 289(6):H2747-51.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.