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Home > Doctors > Joel Palefsky

Joel Palefsky, M.D.

Infectious disease specialist

Dr. Joel Palefsky is an expert in infectious diseases and cancers associated with these diseases. His expertise includes the treatment of anal dysplasia, a pre-cancerous condition that may lead to anal cancer and that is caused by the human papillomavirus (HPV). Anal dysplasia occurs in men and women and is especially common among patients infected with the human immunodeficiency virus (HIV). He also specializes in the biology and development of new treatments for HPV and Epstein-Barr virus.

Palefsky earned a medical degree at McGill University in Montreal, Canada and completed a fellowship in infectious disease at Stanford University. He is the founder and president of the International Anal Neoplasia Society and president-elect of the International Papillomavirus Society. He is a professor of medicine and laboratory medicine at UCSF.

Clinics

Dysplasia Clinic
1600 Divisadero St., Fourth Floor
San Francisco, CA 94143
Phone: (415) 353- 7100
Fax: (415) 353- 4298

Hours: Monday to Friday
8 a.m. – 5 p.m.

Conditions & Treatments

More about Joel Palefsky

Additional Languages

French

Education

McGill University 1984

Residencies

McGill University, Internal Medicine 1984

Fellowships

Stanford University, Infectious Disease 1988

Selected Research and Publications

  1. Ortiz AP, Romaguera J, Pérez CM, Otero Y, Soto-Salgado M, Méndez K, Valle Y, Da Costa M, Suarez E, Palefsky J, Tortolero-Luna G. Human papillomavirus infection in women in puerto rico: agreement between physician-collected and self-collected anogenital specimens. J Low Genit Tract Dis. 2013 Apr; 17(2):210-7.
  2. Méndez K, Romaguera J, Pérez CM, Soto-Salgado M, Tortolero-Luna G, Palefsky JM, Ortiz AP. Cervical human papillomavirus infection in a sample of Hispanic women living in Puerto Rico: comparison with cervical cytology reports. P R Health Sci J. 2013 Mar; 32(1):3-7.
  3. Wilkin T, Lee JY, Lensing SY, Stier EA, Goldstone SE, Berry MJ, Jay N, Aboulafia DM, Einstein MH, Saah A, Mitsuyasu RT, Palefsky JM. High-Grade Anal Intraepithelial Neoplasia Among HIV-1-Infected Men Screening for a Multicenter Clinical Trial of a Human Papillomavirus Vaccine. HIV Clin Trials. 2013 Mar-Apr; 14(2):75-9.
  4. Stier EA, Goldstone SE, Einstein MH, Jay N, Berry JM, Wilkin T, Lee JY, Darragh TM, Da Costa M, Panther L, Aboulafia D, Palefsky JM. Safety and efficacy of topical cidofovir to treat high-grade perianal and vulvar intraepithelial neoplasia in HIV-positive men and women. AIDS. 2013 Feb 20; 27(4):545-51.
  5. Darragh TM, Colgan TJ, Thomas Cox J, Heller DS, Henry MR, Luff RD, McCalmont T, Nayar R, Palefsky JM, Stoler MH, Wilkinson EJ, Zaino RJ, Wilbur DC. The Lower Anogenital Squamous Terminology Standardization project for HPV-associated lesions: background and consensus recommendations from the College of American Pathologists and the American Society for Colposcopy and Cervical Pathology. Int J Gynecol Pathol. 2013 Jan; 32(1):76-115.
  6. Colón-López V, Ortiz AP, Del Toro-Mejías LM, García H, Clatts MC, Palefsky J. Awareness and knowledge of Human Papillomavirus (HPV) infection among high-risk men of Hispanic origin attending a Sexually Transmitted Infection (STI) clinic. BMC Infect Dis. 2012; 12:346.
  7. Palefsky JM. Practising high-resolution anoscopy. Sex Health. 2012 Dec; 9(6):580-6.
  8. Chan PK, Zhang C, Park JS, Smith-McCune KK, Palefsky JM, Giovannelli L, Coutlée F, Hibbitts S, Konno R, Settheetham-Ishida W, Chu TY, Ferrera A, Alejandra Picconi M, De Marco F, Woo YL, Raiol T, Piña-Sánchez P, Bae JH, Wong MC, Chirenje MZ, Magure T, Moscicki AB, Fiander AN, Capra G, Young Ki E, Tan Y, Chen Z, Burk RD, Chan MC, Cheung TH, Pim D, Banks L. Geographical distribution and oncogenic risk association of human papillomavirus type 58 E6 and E7 sequence variations. Int J Cancer. 2013 Jun 1; 132(11):2528-36.
  9. Denny LA, Franceschi S, de Sanjosé S, Heard I, Moscicki AB, Palefsky J. Human papillomavirus, human immunodeficiency virus and immunosuppression. Vaccine. 2012 Nov 20; 30 Suppl 5:F168-74.
  10. Moscicki AB, Schiffman M, Burchell A, Albero G, Giuliano AR, Goodman MT, Kjaer SK, Palefsky J. Updating the natural history of human papillomavirus and anogenital cancers. Vaccine. 2012 Nov 20; 30 Suppl 5:F24-33.
  11. Ortiz AP, Colón-López V, Girona-Lozada G, Botello-Harbaum MT, Sheon N, Guiot HM, Román-Torres L, Díaz-Santana MV, Miranda-De LS, Palefsky JM. Report of the 2012 capacity building for HIV-HPV clinical trials recruitment among minority underserved populations of Hispanic origin in Puerto Rico. P R Health Sci J. 2012 Sep; 31(3):185-7.
  12. Couture MC, Page K, Stein ES, Sansothy N, Sichan K, Kaldor J, Evans JL, Maher L, Palefsky J. Cervical human papillomavirus infection among young women engaged in sex work in Phnom Penh, Cambodia: prevalence, genotypes, risk factors and association with HIV infection. BMC Infect Dis. 2012; 12:166.
  13. Keller MJ, Burk RD, Xie X, Anastos K, Massad LS, Minkoff H, Xue X, D'Souza G, Watts DH, Levine AM, Castle PE, Colie C, Palefsky JM, Strickler HD. Risk of cervical precancer and cancer among HIV-infected women with normal cervical cytology and no evidence of oncogenic HPV infection. JAMA. 2012 Jul 25; 308(4):362-9.
  14. Arbyn M, de Sanjosé S, Saraiya M, Sideri M, Palefsky J, Lacey C, Gillison M, Bruni L, Ronco G, Wentzensen N, Brotherton J, Qiao YL, Denny L, Bornstein J, Abramowitz L, Giuliano A, Tommasino M, Monsonego J. EUROGIN 2011 roadmap on prevention and treatment of HPV-related disease. Int J Cancer. 2012 Nov 1; 131(9):1969-82.
  15. Palefsky JM. Antiretroviral therapy and anal cancer: the good, the bad, and the unknown. Sex Transm Dis. 2012 Jul; 39(7):501-3.
  16. Darragh TM, Colgan TJ, Cox JT, Heller DS, Henry MR, Luff RD, McCalmont T, Nayar R, Palefsky JM, Stoler MH, Wilkinson EJ, Zaino RJ, Wilbur DC. The Lower Anogenital Squamous Terminology Standardization Project for HPV-Associated Lesions: background and consensus recommendations from the College of American Pathologists and the American Society for Colposcopy and Cervical Pathology. J Low Genit Tract Dis. 2012 Jul; 16(3):205-42.
  17. Palefsky J, Berry JM, Jay N. Anal cancer screening. Lancet Oncol. 2012 Jul; 13(7):e279-80; author rreply e280.
  18. Darragh TM, Colgan TJ, Cox JT, Heller DS, Henry MR, Luff RD, McCalmont T, Nayar R, Palefsky JM, Stoler MH, Wilkinson EJ, Zaino RJ, Wilbur DC. The Lower Anogenital Squamous Terminology Standardization Project for HPV-Associated Lesions: background and consensus recommendations from the College of American Pathologists and the American Society for Colposcopy and Cervical Pathology. Arch Pathol Lab Med. 2012 Oct; 136(10):1266-97.
  19. Palefsky J. HIV protease inhibitors to prevent progression of cervical intraepithelial neoplasia to cervical cancer: therapeutic opportunities and challenges. AIDS. 2012 May 15; 26(8):1035-6.
  20. Cranston RD, Murphy R, Weiss RE, Da Costa M, Palefsky J, Shoptaw S, Gorbach PM. Anal human papillomavirus infection in a street-based sample of drug using HIV-positive men. Int J STD AIDS. 2012 Mar; 23(3):195-200.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions by logging on to UCSF Profiles.

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