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Jonathan George, M.D., M.P.H.

Head and neck surgeon

Dr. Jonathan R. George is a head and neck surgical oncologist specializing in the surgical management of thyroid and parathyroid disease. However, his expertise encompasses advanced management of all malignancies of the head and neck, including upper aerodigestive tract cancers — such as oral cavity, oropharynx, hypopharynx, and larynx cancers — as well as advanced skin cancers, salivary gland tumors and skull base malignancies. George is a member of the UCSF Head and Neck Oncologic and Endocrine Surgery team, which is based within the UCSF Bakar Cancer Hospital at UCSF Medical Center's new Mission Bay campus in San Francisco.

George is certified by the American Board of Otolaryngology. He is a fellow of the American Head and Neck Society and the American Thyroid Association.

George's academic pursuits are directed toward clinical and translational investigations into thyroid and squamous cell cancers. He is engaged in multi-institutional clinical trials to advance targeted treatment of head and neck cancers through UCSF's National Cancer Institute-designated Helen Diller Family Comprehensive Cancer Center and its Clinical and Translational Sciences Institute.

George earned a B.A. from Amherst College and an M.D. from Duke University School of Medicine, both with honors distinction. He also received an M.P.H. from the University of North Carolina at Chapel Hill School of Public Health for his studies on the epidemiology of head and neck cancer. He completed a two-year clinical/translational research fellowship studying head and neck cancer at the University of North Carolina at Chapel Hill. He then completed residency in Otolaryngology—Head and Neck Surgery at UCSF Medical Center, followed by advanced fellowship training in head and neck surgical oncology at M.D. Anderson Cancer Center in Houston, Texas. There he pursued rigorous, mentored surgical training in advanced thyroid cancer with Dr. Gary Clayman.

George is committed to providing exceptional, direct-access patient care and is available for short-notice consultations for all head and neck and thyroid cancer patients. To request an appointment, please call his clinic at the number listed below or email him at


Head and Neck Surgery Cancer Clinic
1825 Fourth St., Fourth Floor
San Francisco, CA 94158
Phone: (415) 885–7528
Fax: (415) 885–7711

Hours: Monday to Friday
8 a.m. – 5 p.m.

Thyroid and Parathyroid Surgery
2380 Sutter St., Second Floor
San Francisco, CA 94115
Phone: (415) 885–7528
Fax: (415) 885–7711

Hours: Monday to Friday, 8 a.m. – 5 p.m.

Conditions & Treatments

More about Jonathan George


Duke University School of Medicine 2008


UCSF Medical Center, Otolaryngology – Head and Neck Surgery 2013


M.D. Anderson Cancer Center, Advanced Head and Neck Surgical Oncology Fellowship 2014

Selected Research and Publications

  1. George JR, Yom SS, Wang SJ. Improved outcomes in adjuvant radiotherapy for oral cavity carcinoma at an academic center: a matched-pair analysis. Laryngoscope. 2014 Jul; 124(7):1603-8.
  2. George JR, Yom SS, Wang SJ. Combined modality treatment outcomes for head and neck cancer: comparison of postoperative radiation therapy at academic vs nonacademic medical centers. JAMA Otolaryngol Head Neck Surg. 2013 Nov; 139(11):1118-26.
  3. Clark AJ, Jahangiri A, Garcia RM, George JR, Sughrue ME, McDermott MW, El-Sayed IH, Aghi MK. Endoscopic surgery for tuberculum sellae meningiomas: a systematic review and meta-analysis. Neurosurg Rev. 2013 Jul; 36(3):349-59.
  4. Bissell DM, Roulot D, George J. Transforming growth factor beta and the liver. Hepatology. 2001 Nov; 34(5):859-67.
  5. George J, Wang SS, Sevcsik AM, Sanicola M, Cate RL, Koteliansky VE, Bissell DM. Transforming growth factor-beta initiates wound repair in rat liver through induction of the EIIIA-fibronectin splice isoform. Am J Pathol. 2000 Jan; 156(1):115-24.
  6. George J, Roulot D, Koteliansky VE, Bissell DM. In vivo inhibition of rat stellate cell activation by soluble transforming growth factor beta type II receptor: a potential new therapy for hepatic fibrosis. Proc Natl Acad Sci U S A. 1999 Oct 26; 96(22):12719-24.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.