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Lianne Gensler, M.D.

Director, Ankylosing Spondylitis Clinic

Dr. Lianne Gensler is a rheumatologist at UCSF Medical Center and director of the Ankylosing Spondylitis Clinic, which treats an inflammatory disease that primarily causes pain and inflammation in the spine and the joints between the spine and pelvis.

Gensler earned a medical degree at the University of California, Irvine. She completed an internal medicine residency, chief residency and rheumatology fellowship at UCSF and then joined the medical staff in Rheumatology. Her primary research interest is in studying the disease progression of ankylosing spondylitis and identifying the predictors of osteoporosis development in patients with systemic lupus erythematosus. She is an assistant clinical professor of medicine at UCSF.


Ankylosing Spondylitis Clinic
400 Parnassus Ave., Floor B1
San Francisco, CA 94143
Phone: (415) 353–2305
Fax: (415) 353–2530

Hours: Monday to Friday; 8 a.m. to 4 p.m.

Rheumatoid Arthritis Clinic
400 Parnassus Ave., Floor B-1
San Francisco, CA 94143
Phone: (415) 353-2497
Fax: (415) 353-2530

Hours: Monday to Friday,
8 a.m. – 4 p.m.

Rheumatology Clinic
400 Parnassus Ave., Floor B1
San Francisco, CA 94143
Phone: (415) 353-2497
Fax: (415) 353-2530

Hours: Monday to Friday,
8 a.m. to 4 p.m.

Conditions & Treatments

More about Lianne Gensler


UC Irvine School of Medicine 2001


UCSF Medical Center, Internal Medicine 2005


UCSF Medical Center, Rheumatology 2008

Selected Research and Publications

  1. Sun NZ, Brezinski EA, Berliner J, Haemel A, Connolly MK, Gensler L, McCalmont TH, Shinkai K. Updates in adult-onset Still disease: Atypical cutaneous manifestations and associations with delayed malignancy. J Am Acad Dermatol. 2015 Jun 5.
  2. Cortes A, Pulit SL, Leo PJ, Pointon JJ, Robinson PC, Weisman MH, Ward M, Gensler LS, Zhou X, Garchon HJ, Chiocchia G, Nossent J, Lie BA, Førre Ø, Tuomilehto J, Laiho K, Bradbury LA, Elewaut D, Burgos-Vargas R, Stebbings S, Appleton L, Farrah C, Lau J, Haroon N, Mulero J, Blanco FJ, Gonzalez-Gay MA, Lopez-Larrea C, Bowness P, Gaffney K, Gaston H, Gladman DD, Rahman P, Maksymowych WP, Crusius JB, van der Horst-Bruinsma IE, Valle-Oñate R, Romero-Sánchez C, Hansen IM, Pimentel-Santos FM, Inman RD, Martin J, Breban M, Wordsworth BP, Reveille JD, Evans DM, de Bakker PI, Brown MA. Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1. Nat Commun. 2015; 6:7146.
  3. Gensler LS. Axial spondyloarthritis: the heart of the matter. Clin Rheumatol. 2015 May 10.
  4. Robinson PC, Costello ME, Leo P, Bradbury LA, Hollis K, Cortes A, Lee S, Joo KB, Shim SC, Weisman M, Ward M, Zhou X, Garchon HJ, Chiocchia G, Nossent J, Lie BA, Førre Ø, Tuomilehto J, Laiho K, Jiang L, Liu Y, Wu X, Elewaut D, Burgos-Vargas R, Gensler LS, Stebbings S, Haroon N, Mulero J, Fernandez-Sueiro JL, Gonzalez-Gay MA, Lopez-Larrea C, Bowness P, Gafney K, Gaston JS, Gladman DD, Rahman P, Maksymowych WP, Xu H, van der Horst-Bruinsma IE, Chou CT, Valle-Oñate R, Romero-Sánchez MC, Hansen IM, Pimentel-Santos FM, Inman RD, Martin J, Breban M, Evans D, Reveille JD, Kim TH, Wordsworth BP, Brown MA. ERAP2 is associated with ankylosing spondylitis in HLA-B27-positive and HLA-B27-negative patients. Ann Rheum Dis. 2015 Apr 27.
  5. Deodhar A, Sieper J, Reveille JD, van der Heijde D, Gensler LS, Landewé R. Reply. Arthritis Rheumatol. 2015 Mar; 67(3):856-7.
  6. Robinson PC, Claushuis TA, Cortes A, Martin TM, Evans DM, Leo P, Mukhopadhyay P, Bradbury LA, Cremin K, Harris J, Maksymowych WP, Inman RD, Rahman P, Haroon N, Gensler L, Powell JE, van der Horst-Bruinsma IE, Hewitt AW, Craig JE, Lim LL, Wakefield D, McCluskey P, Voigt V, Fleming P. Genetic dissection of acute anterior uveitis reveals similarities and differences in associations observed with ankylosing spondylitis. Arthritis Rheumatol. 2015 Jan; 67(1):140-51.
  7. Poddubnyy D, Gensler LS. Spontaneous, drug-induced, and drug-free remission in peripheral and axial spondyloarthritis. Best Pract Res Clin Rheumatol. 2014 Oct; 28(5):807-18.
  8. Deodhar A, Reveille JD, van den Bosch F, Braun J, Burgos-Vargas R, Caplan L, Clegg DO, Colbert RA, Gensler LS, van der Heijde D, van der Horst-Bruinsma IE, Inman RD, Maksymowych WP, Mease PJ, Raychaudhuri S, Reimold A, Rudwaleit M, Sieper J, Weisman MH, Landewé RB. The concept of axial spondyloarthritis: joint statement of the spondyloarthritis research and treatment network and the Assessment of SpondyloArthritis international Society in response to the US Food and Drug Administration's comments and concerns. Arthritis Rheumatol. 2014 Oct; 66(10):2649-56.
  9. Assassi S, Weisman MH, Lee M, Savage L, Diekman L, Graham TA, Rahbar MH, Schall JI, Gensler LS, Deodhar AA, Clegg DO, Colbert RA, Reveille JD. New population-based reference values for spinal mobility measures based on the 2009-2010 National Health and Nutrition Examination Survey. Arthritis Rheumatol. 2014 Sep; 66(9):2628-37.
  10. Cortes A, Maksymowych WP, Wordsworth BP, Inman RD, Danoy P, Rahman P, Stone MA, Corr M, Gensler LS, Gladman D, Morgan A, Marzo-Ortega H, Ward MM. Association study of genes related to bone formation and resorption and the extent of radiographic change in ankylosing spondylitis. Ann Rheum Dis. 2014 Apr 10.
  11. Fatemi G, Gensler LS, Learch TJ, Weisman MH. Spine fractures in ankylosing spondylitis: a case report and review of imaging as well as predisposing factors to falls and fractures. Semin Arthritis Rheum. 2014 Aug; 44(1):20-4.
  12. Maksymowych WP, Learch T, Lambert RG, Ward M, Haroon N, Inman R, Salonen D, Gensler LS, Weisman MH. Development and validation of the spondyloarthritis radiography module for calibration of readers using the modified Stoke Ankylosing Spondylitis Spine Score. Arthritis Care Res (Hoboken). 2014 Jan; 66(1):55-62.
  13. Haroon N, Inman RD, Learch TJ, Weisman MH, Lee M, Rahbar MH, Ward MM, Reveille JD, Gensler LS. The impact of tumor necrosis factor a inhibitors on radiographic progression in ankylosing spondylitis. Arthritis Rheum. 2013 Oct; 65(10):2645-54.
  14. Zhou X, Wang J, Zou H, Ward MM, Weisman MH, Espitia MG, Xiao X, Petersdorf E, Mignot E, Martin J, Gensler LS, Scheet P, Reveille JD. MICA, a gene contributing strong susceptibility to ankylosing spondylitis. Ann Rheum Dis. 2014 Aug; 73(8):1552-7.
  15. Belani H, Gensler L, Bajpai U, Meinhardt E, Graf J, Pincus L, Leslie KS. Neutrophilic urticaria with systemic inflammation: a case series. JAMA Dermatol. 2013 Apr; 149(4):453-8.
  16. Gensler LS. Glucocorticoids: complications to anticipate and prevent. Neurohospitalist. 2013 Apr; 3(2):92-7.
  17. Bethi S, Dasgupta A, Weisman MH, Learch TJ, Gensler LS, Davis JC, Reveille JD, Ward MM. Functional limitations due to axial and peripheral joint impairments in patients with ankylosing spondylitis: are focused measures more informative? Arthritis Care Res (Hoboken). 2013 Apr; 65(4):607-14.
  18. Yazdany J, Schmajuk G, Robbins M, Daikh D, Beall A, Yelin E, Barton J, Carlson A, Margaretten M, Zell J, Gensler LS, Kelly V, Saag K, King C. Choosing wisely: the American College of Rheumatology's Top 5 list of things physicians and patients should question. Arthritis Care Res (Hoboken). 2013 Mar; 65(3):329-39.
  19. Ward MM, Learch TJ, Gensler LS, Davis JC, Reveille JD, Weisman MH. Regional radiographic damage and functional limitations in patients with ankylosing spondylitis: differences in early and late disease. Arthritis Care Res (Hoboken). 2013 Feb; 65(2):257-65.
  20. Gensler L, Inman R, Deodhar A. The "knowns" and "unknowns" of biologic therapy in ankylosing spondylitis. Am J Med Sci. 2012 May; 343(5):360-3.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.