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Linda C. Giudice, Ph.D., M.D.

Obstetrician, gynecologist and reproductive endocrinologist

Dr. Linda Giudice is an obstetrician, gynecologist and reproductive endocrinologist at UCSF Medical Center. She specializes in endometriosis, implantation and ovulatory disorders, infertility and assisted reproduction. She also is professor and chair of Obstetrics, Gynecology and Reproductive Sciences at the UCSF School of Medicine. In her research, she focuses on endometrial biology and placental-uterine interactions as well as environmental impacts on reproductive health.

Giudice earned a Ph.D. in biochemistry at UCLA and completed a postdoctoral fellowship at Rockefeller University, working under Nobel Laureate Gunter Blobel. She earned a medical degree at Stanford University and completed a residency in obstetrics and gynecology at Stanford and Washington University in St. Louis as well as a fellowship in reproductive endocrinology and infertility at Stanford. She served as director of the reproductive endocrinology and infertility division at Stanford before joining UCSF in 2005. Giudice is president-elect of the American Society for Reproductive Medicine and a member of the Institute of Medicine of the National Academy of Sciences.

Clinics

Center for Reproductive Health
2356 Sutter St., Seventh Floor
San Francisco, CA 94115
Phone: (415) 353-7475
Fax: (415) 353-7744

Hours: Monday to Friday
8 a.m. – 4:45 p.m.
Saturday and Sunday apts. available for patients undergoing treatment

Conditions & Treatments

More about Linda C. Giudice

Education

Stanford School of Medicine 1982

Residencies

Stanford University Medical Center, Obstetrics & Gynecology 1984
Barnes-Jewish Hospital, Obstetrics & Gynecology 1986

Fellowships

Stanford University Medical Center, Reproductive Endocrinology and Infertility

Selected Research and Publications

  1. Afshar Y, Hastings J, Roqueiro D, Jeong JW, Giudice LC, Fazleabas AT. Changes in eutopic endometrial gene expression during the progression of experimental endometriosis in the baboon, papio anubis. Biol Reprod. 2013; 88(2):44.
  2. Rogers PA, D'Hooghe TM, Fazleabas A, Giudice LC, Montgomery GW, Petraglia F, Taylor RN. Defining future directions for endometriosis research: workshop report from the 2011 world congress of endometriosis in montpellier, france. Reprod Sci. 2013 May; 20(5):483-99.
  3. Louis GM, Peterson CM, Chen Z, Hediger ML, Croughan MS, Sundaram R, Stanford JB, Fujimoto VY, Varner MW, Giudice LC, Kennedy A, Sun L, Wu Q, Kannan K. Perfluorochemicals and endometriosis: the ENDO study. Epidemiology. 2012 Nov; 23(6):799-805.
  4. Meldrum DR, Chang RJ, Giudice LC, Balasch J, Barbieri RL. Role of decreased androgens in the ovarian response to stimulation in older women. Fertil Steril. 2013 Jan; 99(1):5-11.
  5. Alvarez P, Chen X, Hendrich J, Irwin JC, Green PG, Giudice LC, Levine JD. Ectopic uterine tissue as a chronic pain generator. Neuroscience. 2012 Dec 6; 225:269-82.
  6. Burney RO, Giudice LC. Pathogenesis and pathophysiology of endometriosis. Fertil Steril. 2012 Sep; 98(3):511-9.
  7. Buck Louis GM, Chen Z, Peterson CM, Hediger ML, Croughan MS, Sundaram R, Stanford JB, Varner MW, Fujimoto VY, Giudice LC, Trumble A, Parsons PJ, Kannan K. Persistent lipophilic environmental chemicals and endometriosis: the ENDO Study. Environ Health Perspect. 2012 Jun; 120(6):811-6.
  8. Sutton P, Woodruff TJ, Perron J, Stotland N, Conry JA, Miller MD, Giudice LC. Toxic environmental chemicals: the role of reproductive health professionals in preventing harmful exposures. Am J Obstet Gynecol. 2012 Sep; 207(3):164-73.
  9. Spitzer TL, Rojas A, Zelenko Z, Aghajanova L, Erikson DW, Barragan F, Meyer M, Tamaresis JS, Hamilton AE, Irwin JC, Giudice LC. Perivascular human endometrial mesenchymal stem cells express pathways relevant to self-renewal, lineage specification, and functional phenotype. Biol Reprod. 2012 Feb; 86(2):58.
  10. Pabona JM, Simmen FA, Nikiforov MA, Zhuang D, Shankar K, Velarde MC, Zelenko Z, Giudice LC, Simmen RC. Krüppel-like factor 9 and progesterone receptor coregulation of decidualizing endometrial stromal cells: implications for the pathogenesis of endometriosis. J Clin Endocrinol Metab. 2012 Mar; 97(3):E376-92.
  11. Aghajanova L, Shen S, Rojas AM, Fisher SJ, Irwin JC, Giudice LC. Comparative transcriptome analysis of human trophectoderm and embryonic stem cell-derived trophoblasts reveal key participants in early implantation. Biol Reprod. 2012 Jan; 86(1):1-21.
  12. Hyman RW, Herndon CN, Jiang H, Palm C, Fukushima M, Bernstein D, Vo KC, Zelenko Z, Davis RW, Giudice LC. The dynamics of the vaginal microbiome during infertility therapy with in vitro fertilization-embryo transfer. J Assist Reprod Genet. 2012 Feb; 29(2):105-15.
  13. Leach RE, Jessmon P, Coutifaris C, Kruger M, Myers ER, Ali-Fehmi R, Carson SA, Legro RS, Schlaff WD, Carr BR, Steinkampf MP, Silva S, Leppert PC, Giudice L, Diamond MP, Armant DR. High throughput, cell type-specific analysis of key proteins in human endometrial biopsies of women from fertile and infertile couples. Hum Reprod. 2012 Mar; 27(3):814-28.
  14. Zelenko Z, Aghajanova L, Irwin JC, Giudice LC. Nuclear receptor, coregulator signaling, and chromatin remodeling pathways suggest involvement of the epigenome in the steroid hormone response of endometrium and abnormalities in endometriosis. Reprod Sci. 2012 Feb; 19(2):152-62.
  15. White WB, Grady D, Giudice LC, Berry SM, Zborowski J, Snabes MC. A cardiovascular safety study of LibiGel (testosterone gel) in postmenopausal women with elevated cardiovascular risk and hypoactive sexual desire disorder. Am Heart J. 2012 Jan; 163(1):27-32.
  16. Fisher SJ, Giudice LC. SGK1: a fine balancing act for human pregnancy. Nat Med. 2011; 17(11):1348-9.
  17. Buck Louis GM, Hediger ML, Peterson CM, Croughan M, Sundaram R, Stanford J, Chen Z, Fujimoto VY, Varner MW, Trumble A, Giudice LC. Incidence of endometriosis by study population and diagnostic method: the ENDO study. Fertil Steril. 2011 Aug; 96(2):360-5.
  18. Landi A, Tarantino R, Marotta N, Ruggeri AG, Domenicucci M, Giudice L, Martini S, Rastelli M, Ferrazza G, De Luca N, Tomei G, Delfini R. The use of platelet gel in postero-lateral fusion: preliminary results in a series of 14 cases. Eur Spine J. 2011 May; 20 Suppl 1:S61-7.
  19. Savaris RF, Groll JM, Young SL, DeMayo FJ, Jeong JW, Hamilton AE, Giudice LC, Lessey BA. Progesterone resistance in PCOS endometrium: a microarray analysis in clomiphene citrate-treated and artificial menstrual cycles. J Clin Endocrinol Metab. 2011 Jun; 96(6):1737-46.
  20. Sheldon E, Vo KC, McIntire RA, Aghajanova L, Zelenko Z, Irwin JC, Giudice LC. Biobanking human endometrial tissue and blood specimens: standard operating procedure and importance to reproductive biology research and diagnostic development. Fertil Steril. 2011 May; 95(6):2120-2, 2122.e1-12.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions by logging on to UCSF Profiles.