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Liviu Klein, M.D., M.S.


Dr. Liviu Klein, a cardiologist at the UCSF Heart and Vascular Center, is director of the Mechanical Circulatory Support and Heart Failure Device Program. He specializes in treating patients with heart failure and arrhythmias, including patients before and after heart transplants. He also has expertise in cardiac resynchronization and mechanical therapies such as ventricular assist devices for heart failure. In his research, he studies the epidemiology of heart failure in women, including those at risk for sudden cardiac death. Together with colleagues in the department of Bioengineering and Therapeutic Sciences at UCSF, he is developing new technologies for monitoring and treating patients with cardiovascular disease (including heart failure), and for those who use ventricular assist devices.

Klein earned a medical degree at the Carol Davila School of Medicine in Bucharest, Romania, and earned a master's of science in clinical investigation at Northwestern University in Evanston, Ill. He completed a residency in internal medicine at the Advocate Illinois Masonic Medical Center in Chicago and a fellowship in cardiovascular epidemiology at Northwestern University's Feinberg School of Medicine. At Northwestern's McGaw Medical Center in Chicago, he completed fellowships in cardiovascular disease, advanced heart failure and transplantation, and clinical cardiac electrophysiology. Klein is a member of the American Heart Association, Heart Failure Society of America and International Society for Lung and Heart Transplant. He has published more than 60 peer-reviewed articles and books. At UCSF, he is an associate professor of clinical medicine.


Advanced Heart Failure Evaluation and Therapies Program
400 Parnassus Ave., Sixth Floor, Suite A-6110
San Francisco, CA 94143-0118
Phone: (415) 353-4145
Fax: (415) 353-4166

Hours: Thursday 12:30 p.m. - 5 p.m.

Cardiovascular Care and Prevention Center at Mission Bay
535 Mission Bay Blvd. South
San Francisco, CA 94158
Phone: (415) 353-2873
Fax: (415) 353-2528

Hours: Monday to Friday
8 a.m. – 5 p.m.

Heart Transplant Program
400 Parnassus Ave., Sixth Floor
San Francisco, CA 94143
Phone: (415) 353-4145
Fax: (415) 353-4166

Hours: Thursday 12:30 p.m. - 5 p.m.

Conditions & Treatments

More about Liviu Klein


Universitatea De Medicina Si Farmacie, Bucharest Romania 1999


Advocate Illinois Masonic Medical Center, Chicago, Internal Medicine 2003


Northwestern University, Cardiovascular Epidemiology 2005
McGaw Medical Center, Northwestern University, Cardiovascular Disease 2007
McGaw Medical Center, Northwestern University, Advanced Heart Failure and Transplantation 2008
McGaw Medical Center, Northwestern University, Cardiac Electrophysiology 2009

Selected Research and Publications

  1. Klein L, Greenberg BH, Konstam MA, Gregory D, Kociol RD, Johnson MR, De Marco T. Activities and Compensation of Advanced Heart Failure Specialists: Results of the Heart Failure Society of America (HFSA) Survey. J Card Fail. 2015 Sep 8.
  2. Etemadi M, Inan OT, Heller JA, Hersek S, Klein L, Roy S. A Wearable Patch to Enable Long-Term Monitoring of Environmental, Activity and Hemodynamics Variables. IEEE Trans Biomed Circuits Syst. 2015 May 12.
  3. Rogers SE, Klein L, Perissinotto CM. The Importance of Cognitive Assessment Before Ventricular Device Placement: A Teachable Moment. JAMA Intern Med. 2015 Mar 30.
  4. Donneyong MM, Hornung CA, Taylor KC, Baumgartner RN, Myers JA, Eaton CB, Gorodeski EZ, Klein L, Martin LW, Shikany JM, Song Y, Li W, Manson JE. Risk of Heart Failure Among Postmenopausal Women: A Secondary Analysis of the Randomized Trial of Vitamin D Plus Calcium of the Women's Health Initiative. Circ Heart Fail. 2015 Jan; 8(1):49-56.
  5. Wiens A, Etemadi M, Roy S, Klein L, Inan O. Towards Continuous, Non-Invasive Assessment of Ventricular Function and Hemodynamics: Wearable Ballistocardiography. IEEE J Biomed Health Inform. 2014 Sep 23.
  6. Etemadi M, Hersek S, Tseng JM, Rabbani N, Heller JA, Roy S, Klein L, Inan OT. Tracking clinical status for heart failure patients using ballistocardiography and electrocardiography signal features. Conf Proc IEEE Eng Med Biol Soc. 2014 Aug; 2014:5188-91.
  7. Wiens A, Etemadi M, Klein L, Roy S, Inan OT. Wearable ballistocardiography: Preliminary methods for mapping surface vibration measurements to whole body forces. Conf Proc IEEE Eng Med Biol Soc. 2014 Aug; 2014:5172-5.
  8. Klein L, Hsia H. Sudden cardiac death in heart failure. Cardiol Clin. 2014 Feb; 32(1):135-44, ix.
  9. Sridharan L, Klein L. Prognostic factors in patients hospitalized for heart failure. Curr Heart Fail Rep. 2013 Dec; 10(4):380-6.
  10. Perez MV, Wang PJ, Larson JC, Soliman EZ, Limacher M, Rodriguez B, Klein L, Manson JE, Martin LW, Prineas R, Connelly S, Hlatky M, Wassertheil-Smoller S, Stefanick ML. Risk factors for atrial fibrillation and their population burden in postmenopausal women: the Women's Health Initiative Observational Study. Heart. 2013 Aug; 99(16):1173-8.
  11. Perez MV, Wang PJ, Larson JC, Virnig BA, Cochrane B, Curb JD, Klein L, Manson JE, Martin LW, Robinson J, Wassertheil-Smoller S, Stefanick ML. Effects of postmenopausal hormone therapy on incident atrial fibrillation: the Women's Health Initiative randomized controlled trials. Circ Arrhythm Electrophysiol. 2012 Dec; 5(6):1108-16.
  12. Klein L. ACP Journal Club. Review: new oral anticoagulants reduced stroke and systemic embolism compared with warfarin in AF. Ann Intern Med. 2012 Sep 18; 157(6):JC3-2.
  13. Avery CL, Sethupathy P, Buyske S, He Q, Lin DY, Arking DE, Carty CL, Duggan D, Fesinmeyer MD, Hindorff LA, Jeff JM, Klein L, Patton KK, Peters U, Shohet RV, Sotoodehnia N, Young AM, Kooperberg C, Haiman CA, Mohlke KL, Whitsel EA, North KE. Fine-mapping and initial characterization of QT interval loci in African Americans. PLoS Genet. 2012; 8(8):e1002870.
  14. Eaton CB, Abdulbaki AM, Margolis KL, Manson JE, Limacher M, Klein L, Allison MA, Robinson JG, Curb JD, Martin LA, Liu S, Howard BV. Racial and ethnic differences in incident hospitalized heart failure in postmenopausal women: the Women's Health Initiative. Circulation. 2012 Aug 7; 126(6):688-96.
  15. Klein L. Rivaroxaban reduced stroke and systemic embolism compared with warfarin in nonvalvular AF. Ann Intern Med. 2012 Jan 17; 156(2):JC1-2, JC1-3.
  16. Klein L. Apixaban reduced stroke and systemic embolism compared with warfarin in atrial fibrillation. Ann Intern Med. 2012 Jan 17; 156(2):JC1-2, JC1-3.
  17. Shah RU, Winkleby MA, Van Horn L, Phillips LS, Eaton CB, Martin LW, Rosal MC, Manson JE, Ning H, Lloyd-Jones DM, Klein L. Education, income, and incident heart failure in post-menopausal women: the Women's Health Initiative Hormone Therapy Trials. J Am Coll Cardiol. 2011 Sep 27; 58(14):1457-64.
  18. Klein L, Grau-Sepulveda MV, Bonow RO, Hernandez AF, Williams MV, Bhatt DL, Fonarow GC. Quality of care and outcomes in women hospitalized for heart failure. Circ Heart Fail. 2011 Sep; 4(5):589-98.
  19. Klein L. Omnes viae Romam ducunt: Asymptomatic cardiac and noncardiac organ system dysfunction leads to heart failure. Circulation. 2011 Jul 5; 124(1):4-6.
  20. Tempelhof MW, Klein L, Cotts WG, Benzuly KH, Davidson CJ, Meyers SN, McCarthy PM, Malaisrie CS, McGee EC, Beohar N. Clinical experience and patient outcomes associated with the TandemHeart percutaneous transseptal assist device among a heterogeneous patient population. ASAIO J. 2011 Jul-Aug; 57(4):254-61.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.