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Liviu Klein, M.D., M.S.

Cardiologist

Dr. Liviu Klein, a cardiologist at the UCSF Heart and Vascular Center, is director of the Mechanical Circulatory Support and Heart Failure Device Program. He specializes in treating patients with heart failure and arrhythmias, including patients before and after heart transplants. He also has expertise in cardiac resynchronization and mechanical therapies such as ventricular assist devices for heart failure. In his research, he studies the epidemiology of heart failure in women, including those at risk for sudden cardiac death. Together with colleagues in the department of Bioengineering and Therapeutic Sciences at UCSF, he is developing new sensor technologies for monitoring and treating patients with heart failure, and for those who use ventricular assist devices.

Klein earned a medical degree at the Carol Davila School of Medicine in Bucharest, Romania, and earned a master's of science in clinical investigation at Northwestern University in Evanston, Ill. He completed a residency in internal medicine at the Advocate Illinois Masonic Medical Center in Chicago and a fellowship in cardiovascular epidemiology at Northwestern University's Feinberg School of Medicine. At Northwestern's McGaw Medical Center in Chicago, he completed fellowships in cardiovascular disease, advanced heart failure and transplantation, and clinical cardiac electrophysiology. Klein is a member of the American Heart Association, Heart Failure Society of America and International Society for Lung and Heart Transplant. He has published more than 60 peer-reviewed articles and books. At UCSF, he is an assistant professor of clinical medicine.

Clinics

Advanced Heart Failure Evaluation and Therapies Program
400 Parnassus Ave., Sixth Floor, Suite A-6110
San Francisco, CA 94143-0118
Phone: (415) 353-4145
Fax: (415) 353-4166

Hours: Thursday 12:30 p.m. - 5 p.m.

Cardiovascular Care and Prevention Center at Mission Bay
535 Mission Bay Blvd. South
San Francisco, CA 94158
Phone: (415) 353-2873
Fax: (415) 353-2528

Hours: Monday to Friday
8 a.m. – 5 p.m.

Heart Transplant Program
400 Parnassus Ave., Sixth Floor
San Francisco, CA 94143
Phone: (415) 353-4145
Fax: (415) 353-4166

Hours: Thursday 12:30 p.m. - 5 p.m.

Conditions & Treatments

More about Liviu Klein

Education

Universitatea De Medicina Si Farmacie, Bucharest Romania 1999

Residencies

Advocate Illinois Masonic Medical Center, Chicago, Internal Medicine 2003

Fellowships

Northwestern University, Cardiovascular Epidemiology 2005
McGaw Medical Center, Northwestern University, Cardiovascular Disease 2007
McGaw Medical Center, Northwestern University, Advanced Heart Failure and Transplantation 2008
McGaw Medical Center, Northwestern University, Cardiac Electrophysiology 2009

Selected Research and Publications

  1. Donneyong MM, Hornung CA, Taylor KC, Baumgartner RN, Myers JA, Eaton CB, Gorodeski EZ, Klein L, Martin LW, Shikany JM, Song Y, Li W, Manson JE. Risk of Heart Failure Among Postmenopausal Women: A Secondary Analysis of the Randomized Trial of Vitamin D Plus Calcium of the Women's Health Initiative. Circ Heart Fail. 2014 Nov 14.
  2. Wiens A, Etemadi M, Roy S, Klein L, Inan O. Towards Continuous, Non-Invasive Assessment of Ventricular Function and Hemodynamics: Wearable Ballistocardiography. IEEE J Biomed Health Inform. 2014 Sep 23.
  3. Klein L, Hsia H. Sudden cardiac death in heart failure. Cardiol Clin. 2014 Feb; 32(1):135-44.
  4. Sridharan L, Klein L. Prognostic factors in patients hospitalized for heart failure. Curr Heart Fail Rep. 2013 Dec; 10(4):380-6.
  5. Perez MV, Wang PJ, Larson JC, Soliman EZ, Limacher M, Rodriguez B, Klein L, Manson JE, Martin LW, Prineas R, Connelly S, Hlatky M, Wassertheil-Smoller S, Stefanick ML. Risk factors for atrial fibrillation and their population burden in postmenopausal women: the Women's Health Initiative Observational Study. Heart. 2013 Aug; 99(16):1173-8.
  6. Perez MV, Wang PJ, Larson JC, Virnig BA, Cochrane B, Curb JD, Klein L, Manson JE, Martin LW, Robinson J, Wassertheil-Smoller S, Stefanick ML. Effects of postmenopausal hormone therapy on incident atrial fibrillation: the Women's Health Initiative randomized controlled trials. Circ Arrhythm Electrophysiol. 2012 Dec; 5(6):1108-16.
  7. Klein L. ACP Journal Club. Review: new oral anticoagulants reduced stroke and systemic embolism compared with warfarin in AF. Ann Intern Med. 2012 Sep 18; 157(6):JC3-2.
  8. Avery CL, Sethupathy P, Buyske S, He Q, Lin DY, Arking DE, Carty CL, Duggan D, Fesinmeyer MD, Hindorff LA, Jeff JM, Klein L, Patton KK, Peters U, Shohet RV, Sotoodehnia N, Young AM, Kooperberg C, Haiman CA, Mohlke KL, Whitsel EA, North KE. Fine-mapping and initial characterization of QT interval loci in African Americans. PLoS Genet. 2012; 8(8):e1002870.
  9. Eaton CB, Abdulbaki AM, Margolis KL, Manson JE, Limacher M, Klein L, Allison MA, Robinson JG, Curb JD, Martin LA, Liu S, Howard BV. Racial and ethnic differences in incident hospitalized heart failure in postmenopausal women: the Women's Health Initiative. Circulation. 2012 Aug 7; 126(6):688-96.
  10. Klein L. Rivaroxaban reduced stroke and systemic embolism compared with warfarin in nonvalvular AF. Ann Intern Med. 2012 Jan 17; 156(2):JC1-2, JC1-3.
  11. Klein L. Apixaban reduced stroke and systemic embolism compared with warfarin in atrial fibrillation. Ann Intern Med. 2012 Jan 17; 156(2):JC1-2, JC1-3.
  12. Shah RU, Winkleby MA, Van Horn L, Phillips LS, Eaton CB, Martin LW, Rosal MC, Manson JE, Ning H, Lloyd-Jones DM, Klein L. Education, income, and incident heart failure in post-menopausal women: the Women's Health Initiative Hormone Therapy Trials. J Am Coll Cardiol. 2011 Sep 27; 58(14):1457-64.
  13. Klein L, Grau-Sepulveda MV, Bonow RO, Hernandez AF, Williams MV, Bhatt DL, Fonarow GC. Quality of care and outcomes in women hospitalized for heart failure. Circ Heart Fail. 2011 Sep; 4(5):589-98.
  14. Klein L. Omnes viae Romam ducunt: Asymptomatic cardiac and noncardiac organ system dysfunction leads to heart failure. Circulation. 2011 Jul 5; 124(1):4-6.
  15. Tempelhof MW, Klein L, Cotts WG, Benzuly KH, Davidson CJ, Meyers SN, McCarthy PM, Malaisrie CS, McGee EC, Beohar N. Clinical experience and patient outcomes associated with the TandemHeart percutaneous transseptal assist device among a heterogeneous patient population. ASAIO J. 2011 Jul-Aug; 57(4):254-61.
  16. Svetlichnaya J, Klein L. Atrial fibrillation in elderly patients with heart failure: convergence of two cardiovascular epidemics in the 21st Century. Expert Rev Cardiovasc Ther. 2011 Jul; 9(7):903-12.
  17. Shah RU, Tsai V, Klein L, Heidenreich PA. Characteristics and outcomes of very elderly patients after first hospitalization for heart failure. Circ Heart Fail. 2011 May; 4(3):301-7.
  18. Klein L. ACP Journal Club. Higher-dose dabigatran reduced stroke, but not major hemorrhage, more than warfarin in atrial fibrillation. Ann Intern Med. 2010 Jan 19; 152(2):JC1-2.
  19. Shah RU, Klein L, Lloyd-Jones DM. Heart failure in women: epidemiology, biology and treatment. Womens Health (Lond Engl). 2009 Sep; 5(5):517-27.
  20. Klein L, Massie BM, Leimberger JD, O'Connor CM, Piņa IL, Adams KF, Califf RM, Gheorghiade M. Admission or changes in renal function during hospitalization for worsening heart failure predict postdischarge survival: results from the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-CHF). Circ Heart Fail. 2008 May; 1(1):25-33.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.