University of California San Francisco | About UCSF | UCSF Benioff Children's Hospital San Francisco
Search Site | Find a Doctor

Madhulika Varma, M.D.

Colorectal surgeon

Dr. Mika Varma, chief of Colorectal Surgery at UCSF Medical Center, specializes in diseases of the colon, rectum and anus. Her areas of expertise include colorectal and anal cancer, inflammatory bowel diseases such as ulcerative colitis, Crohn's disease, and pelvic floor disorders. She also is a specialist in laparoscopic colorectal surgery, using minimally invasive techniques to treat many of these diseases. Varma is director of the Center for Pelvic Physiology, which evaluates patients with fecal incontinence, constipation, pelvic floor prolapse, rectal cancer and anal fistula. She is co-director of the UCSF Center for Inflammatory Bowel Disease and a member of the clinical team of the Women's Continence Center and the Women's Health Research Center.

Varma earned a medical degree at Brown University School of Medicine in Providence, R.I. She completed a residency in general surgery at UCSF and spent a year at the University of Minnesota for specialized training in colon and rectal surgery. She returned to UCSF in 2000 where she completed a fellowship in Clinical Outcomes Research and Epidemiology. Her research interests include the assessment of clinical outcomes for inflammatory bowel diseases and defecation disorders.


Center for Colorectal Surgery
1825 Fourth St., Fourth Floor
San Francisco, CA 94158
Phone: (415) 885-3606
Fax: (415) 885-7678

Hours: Monday to Friday
8 a.m. – 4:30 p.m.

Center for Pelvic Physiology
1825 Fourth St., Fourth Floor
San Francisco, CA 94158
Urinary Incontinence and Urodynamics Testing: (415) 885-7788
All Other Appointments: (415) 885-7673
Fax: (415) 885-7678

Hours: Office open Monday to Friday, 9 a.m. – 4:30 p.m.

Appointment hours vary

Conditions & Treatments

More about Madhulika Varma

Additional Languages



Brown University School of Medicine 1991


UCSF Medical Center, General Surgery 1998


University of Minnesota, Colon and Rectal Surgery 2000

Selected Research and Publications

  1. Wang ED, Conkling N, Xu X, Chern H, Finlayson E, Varma MG, Hansen SL, Foster RD, Hoffman WY, Sbitany H. Perineal Flap Reconstruction following Oncologic Anorectal Extirpation: An Outcomes Assessment. Plast Reconstr Surg. 2015 Jan; 135(1):176e-84e.
  2. Wang ED, Conkling N, Xu X, Chern H, Finlayson E, Varma MG, Hansen SL, Foster RD, Hoffman WY, Sbitany H. Perineal reconstruction following anorectal tumor resection: an 18-year single-center experience. Plast Reconstr Surg. 2014 Oct; 134(4 Suppl 1):136-7.
  3. Cohan JN, Varma MG. Simple interventions for complex complications: moving surgery forward. Dis Colon Rectum. 2014 Jan; 57(1):3-4.
  4. Albiani JJ, Hart SL, Katz L, Berian J, Del Rosario A, Lee J, Varma M. Impact of depression and anxiety on the quality of life of constipated patients. J Clin Psychol Med Settings. 2013 Mar; 20(1):123-32.
  5. Imhoff LR, Liwanag L, Varma M. Exacerbation of symptom severity of pelvic floor disorders in women who report a history of sexual abuse. Arch Surg. 2012 Dec 1; 147(12):1123-9.
  6. Finlayson E, Zhao S, Varma MG. Outcomes after rectal cancer surgery in elderly nursing home residents. Dis Colon Rectum. 2012 Dec; 55(12):1229-35.
  7. Imhoff LR, Brown JS, Creasman JM, Subak LL, Van den Eeden SK, Thom DH, Varma MG, Huang AJ. Fecal incontinence decreases sexual quality of life, but does not prevent sexual activity in women. Dis Colon Rectum. 2012 Oct; 55(10):1059-65.
  8. Steele SR, Varma MG, Melton GB, Ross HM, Rafferty JF, Buie WD. Practice parameters for anal squamous neoplasms. Dis Colon Rectum. 2012 Jul; 55(7):735-49.
  9. Hart SL, Lee JW, Berian J, Patterson TR, Del Rosario A, Varma MG. A randomized controlled trial of anorectal biofeedback for constipation. Int J Colorectal Dis. 2012 Apr; 27(4):459-66.
  10. Hart SL, Albiani JJ, Crangle CJ, Torbit LA, Varma MG. Development and assessment of the constipation-related disability scale. Aliment Pharmacol Ther. 2012 Jan; 35(1):183-92.
  11. Varma M, Rafferty J, Buie WD. Practice parameters for the management of rectal prolapse. Dis Colon Rectum. 2011 Nov; 54(11):1339-46.
  12. Chen Z, Liu Z, Li W, Qu K, Deng X, Varma MG, Fichera A, Pigazzi A, Garcia-Aguilar J. Chromosomal copy number alterations are associated with tumor response to chemoradiation in locally advanced rectal cancer. Genes Chromosomes Cancer. 2011 Sep; 50(9):689-99.
  13. Wang JY, Hart SL, Wilkowski KS, Lee JW, Delmotte EC, del Rosario KM, del Rosario AS, Varma MG. Gender-specific differences in pelvic organ function after proctectomy for inflammatory bowel disease. Dis Colon Rectum. 2011 Jan; 54(1):66-76.
  14. Varma MG. Sew or staple: does it make a difference? Inflamm Bowel Dis. 2011 Apr; 17(4):1046-7.
  15. McCrea GL, Miaskowski C, Stotts NA, Macera L, Paul SM, Varma MG. Age differences in patients evaluated for constipation: constipation characteristics, symptoms, and bowel and dietary habits. J Wound Ostomy Continence Nurs. 2010 Nov-Dec; 37(6):667-76.
  16. Pastor C, Baek JH, Varma MG, Kim E, Indorf LA, Garcia-Aguilar J. Validation of the risk index category as a predictor of surgical site infection in elective colorectal surgery. Dis Colon Rectum. 2010 May; 53(5):721-7.
  17. Pastor C, Artinyan A, Varma MG, Kim E, Gibbs L, Garcia-Aguilar J. An increase in compliance with the Surgical Care Improvement Project measures does not prevent surgical site infection in colorectal surgery. Dis Colon Rectum. 2010 Jan; 53(1):24-30.
  18. Wang J, Varma MG, Creasman JM, Subak LL, Brown JS, Thom DH, van den Eeden SK. Pelvic floor disorders and quality of life in women with self-reported irritable bowel syndrome. Aliment Pharmacol Ther. 2010 Feb 1; 31(3):424-31.
  19. Wang JY, Hart SL, Lee J, Berian JR, McCrea GL, Varma MG. A valid and reliable measure of constipation-related quality of life. Dis Colon Rectum. 2009 Aug; 52(8):1434-42.
  20. Wang JY, Garcia-Aguilar J, Sternberg JA, Abel ME, Varma MG. Treatment of transsphincteric anal fistulas: are fistula plugs an acceptable alternative? Dis Colon Rectum. 2009 Apr; 52(4):692-7.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.