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Manish Kumar Aghi, Ph.D., M.D.

Neurosurgeon

Dr. Manish Aghi is a neurosurgeon specializing in adult brain tumors at UCSF Medical Center. He cares for patients with a wide range of conditions, including astrocytomas, oligodendrogliomas, anaplastic astrocytomas, glioblastomas, meningiomas, and pituitary adenomas. As principal investigator at the UCSF Brain Tumor Research Center, his research interests include glioblastoma angiogenesis, mechanisms of glioblastoma resistance to anti-angiogenic therapy, and experimental glioblastoma therapies like oncolytic viruses.

Aghi earned a medical degree and a doctoral degree in neurosciences from Harvard Medical School and completed a neurosurgery residency at Massachusetts General Hospital. He is a member of the Society for Neuro-oncology, American Association of Neurological Surgeons, Congress of Neurologic Surgeons and Pituitary Network Association. Among his honors are the Ronald L. Bittner Award; Preuss Award and Mahaley Award from the American Association of Neurological Surgeons; and the Synthes Skull Base Award and the Integra Foundation Award from the Congress of Neurological Surgeons. He is an assistant professor in residence in neurological surgery at UCSF.

Clinics

California Center for Pituitary Disorders
400 Parnassus Ave., Eighth Floor
San Francisco, CA 94143
Phone: (866) 559-5543

Fax: (415) 353-2889

Hours: Monday to Friday
8 a.m. – 5 p.m.

Neuro-Oncology Clinic
400 Parnassus Ave., Eighth Floor
San Francisco, CA 94143
Phone: (415) 353-2966
Fax: (415) 353-2167

Hours: Monday to Friday
8 a.m. – 5 p.m.

Neurosurgery Clinic
400 Parnassus Ave., Eighth Floor
San Francisco, CA 94143
Phone: (415) 353-7500
Fax: (415) 353-2889

Hours: Monday to Friday
8 a.m. – 4:30 p.m.

Conditions & Treatments

More about Manish Kumar Aghi

Education

Harvard Medical School 2000

Residencies

Massachusetts General Hospital, Neurosurgery 2007

Selected Research and Publications

  1. Jahangiri A, Wagner J, Han SW, Tran MT, Miller LM, Tom MW, Ostling LR, Kunwar S, Blevins L, Aghi MK. Rate and time course of improvement in endocrine function after more than 1000 pituitary operations. Neurosurgery. 2014 Aug; 61 Suppl 1:163-6.
  2. Jahangiri A, Wagner J, Han SW, Zygourakis CC, Han SJ, Tran MT, Miller LM, Tom MW, Kunwar S, Blevins LS, Aghi MK. Morbidity of repeat transsphenoidal surgery assessed in more than 1000 operations. J Neurosurg. 2014 Jul; 121(1):67-74.
  3. Burke K, Benet A, Aghi MK, El-Sayed I. Impact of platybasia and anatomic variance on surgical approaches to the craniovertebral junction. Laryngoscope. 2014 Aug; 124(8):1760-6.
  4. Ivan ME, J Han S, Aghi MK. Tumors of the anterior skull base. Expert Rev Neurother. 2014 Apr; 14(4):425-38.
  5. Safaee M, Sun MZ, Oh T, Aghi MK, Berger MS, McDermott MW, Parsa AT, Bloch O. Use of thrombin-based hemostatic matrix during meningioma resection: A potential risk factor for perioperative thromboembolic events. Clin Neurol Neurosurg. 2014 Apr; 119:116-20.
  6. Potts MB, Shah JK, Molinaro AM, Blevins LS, Tyrrell JB, Kunwar S, Dowd CF, Hetts SW, Aghi MK. Cavernous and inferior petrosal sinus sampling and dynamic magnetic resonance imaging in the preoperative evaluation of Cushing's disease. J Neurooncol. 2014 Feb; 116(3):593-600.
  7. Castro BA, Aghi MK. Getting more out of radiation therapy in glioblastoma. Neuro Oncol. 2014 Jan; 16(1):4-6.
  8. Bloch O, Crane CA, Fuks Y, Kaur R, Aghi MK, Berger MS, Butowski NA, Chang SM, Clarke JL, McDermott MW, Prados MD, Sloan AE, Bruce JN, Parsa AT. Heat-shock protein peptide complex-96 vaccination for recurrent glioblastoma: a phase II, single-arm trial. Neuro Oncol. 2014 Jan; 16(2):274-9.
  9. Jahangiri A, Aghi MK, Carbonell WS. 1 Integrin: Critical Path to Antiangiogenic Therapy Resistance and Beyond. Cancer Res. 2014 Jan 1; 74(1):3-7.
  10. Jahangiri A, Potts M, Kunwar S, Blevins L, El-Sayed IH, Aghi MK. Extended endoscopic endonasal approach for suprasellar Rathke's cleft cysts. J Clin Neurosci. 2014 May; 21(5):779-85.
  11. Awad AJ, Rowland NC, Mian M, Hiniker A, Tate M, Aghi MK. Etiology, prognosis, and management of secondary pituitary abscesses forming in underlying pituitary adenomas. J Neurooncol. 2014 May; 117(3):469-76.
  12. Ayodele MO, Pekmezci M, Aghi MK, Scott BJ. Headache and focal neurologic deficits in a 37-year-old woman. JAMA Neurol. 2013 Nov 1; 70(11):1445-9.
  13. Han SJ, Rolston JD, Jahangiri A, Aghi MK. Rathke's cleft cysts: review of natural history and surgical outcomes. J Neurooncol. 2014 Apr; 117(2):197-203.
  14. Jahangiri A, Wagner J, Tran MT, Miller LM, Tom MW, Kunwar S, Blevins L, Aghi MK. Factors predicting postoperative hyponatremia and efficacy of hyponatremia management strategies after more than 1000 pituitary operations. J Neurosurg. 2013 Dec; 119(6):1478-83.
  15. Jahangiri A, Clark AJ, Han SJ, Kunwar S, Blevins LS, Aghi MK. Socioeconomic factors associated with pituitary apoplexy. J Neurosurg. 2013 Dec; 119(6):1432-6.
  16. Jahangiri A, Wagner JR, Pekmezci M, Hiniker A, Chang EF, Kunwar S, Blevins L, Aghi MK. A comprehensive long-term retrospective analysis of silent corticotrophic adenomas vs hormone-negative adenomas. Neurosurgery. 2013 Jul; 73(1):8-17; discussion 17-8.
  17. Bloch O, Safaee M, Sun MZ, Butowski NA, McDermott MW, Berger MS, Aghi MK, Parsa AT. Disseminated progression of glioblastoma after treatment with bevacizumab. Clin Neurol Neurosurg. 2013 Sep; 115(9):1795-801.
  18. Carbonell WS, DeLay M, Jahangiri A, Park CC, Aghi MK. 1 integrin targeting potentiates antiangiogenic therapy and inhibits the growth of bevacizumab-resistant glioblastoma. Cancer Res. 2013 May 15; 73(10):3145-54.
  19. Hiniker A, Hagenkord JM, Powers MP, Aghi MK, Prados MD, Perry A. Gliosarcoma arising from an oligodendroglioma (oligosarcoma). Clin Neuropathol. 2013 May-Jun; 32(3):165-70.
  20. Ameri K, Rajah AM, Nguyen V, Sanders TA, Jahangiri A, Delay M, Donne M, Choi HJ, Tormos KV, Yeghiazarians Y, Jeffrey SS, Rinaudo PF, Rowitch DH, Aghi M, Maltepe E. Nuclear localization of the mitochondrial factor HIGD1A during metabolic stress. PLoS One. 2013; 8(4):e62758.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.