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Mark Ratcliffe, M.D.

Heart surgeon

Education

Case Western Reserve University 1981

Residencies

University of Pennsylvania, General Surgery 1988

Fellowships

University of Pennsylvania, Cardiothoracic Surgery 1991

Selected Research and Publications

  1. Yaffee DW, Grossi EA, Ratcliffe MB. Progressive design concepts in off-pump left ventricular remodeling mitral valve repair devices. Ann Cardiothorac Surg. 2015 Jul; 4(4):352-4.
  2. Ratcliffe M, Cambronero N, Takaba K, Ge L. Studies on postinfarct left ventricular remodeling: state of the art. Ann Thorac Surg. 2015 Mar; 99(3):755-6.
  3. Morrel WG, Ge L, Zhang Z, Grossi EA, Guccione JM, Ratcliffe MB. Effect of mitral annuloplasty device shape and size on leaflet and myofiber stress following repair of posterior leaflet prolapse: a patient-specific finite element simulation. J Heart Valve Dis. 2014 Nov; 23(6):727-34.
  4. Lovett DH, Chu C, Wang G, Ratcliffe MB, Baker AJ. A N-terminal truncated intracellular isoform of matrix metalloproteinase-2 impairs contractility of mouse myocardium. Front Physiol. 2014; 5:363.
  5. Pantoja JL, Ge L, Zhang Z, Morrel WG, Guccione JM, Grossi EA, Ratcliffe MB. Posterior papillary muscle anchoring affects remote myofiber stress and pump function: finite element analysis. Ann Thorac Surg. 2014 Oct; 98(4):1355-62.
  6. Shimkunas R, Makwana O, Spaulding K, Bazargan M, Khazalpour M, Takaba K, Soleimani M, Myagmar BE, Lovett DH, Simpson PC, Ratcliffe MB, Baker AJ. Myofilament dysfunction contributes to impaired myocardial contraction in the infarct border zone. Am J Physiol Heart Circ Physiol. 2014 Oct 15; 307(8):H1150-8.
  7. Lee LC, Ge L, Zhang Z, Pease M, Nikolic SD, Mishra R, Ratcliffe MB, Guccione JM. Patient-specific finite element modeling of the Cardiokinetix Parachute() device: effects on left ventricular wall stress and function. Med Biol Eng Comput. 2014 Jun; 52(6):557-66.
  8. Ratcliffe M, Cambronero N, Long S. Invited commentary. Ann Thorac Surg. 2014 May; 97(5):1524-5.
  9. Lee LC, Genet M, Dang AB, Ge L, Guccione JM, Ratcliffe MB. Applications of computational modeling in cardiac surgery. J Card Surg. 2014 May; 29(3):293-302.
  10. Ge L, Morrel WG, Ward A, Mishra R, Zhang Z, Guccione JM, Grossi EA, Ratcliffe MB. Measurement of mitral leaflet and annular geometry and stress after repair of posterior leaflet prolapse: virtual repair using a patient-specific finite element simulation. Ann Thorac Surg. 2014 May; 97(5):1496-503.
  11. Ratcliffe MB, Wozniak CJ. Invited commentary. Ann Thorac Surg. 2014 Mar; 97(3):907-8.
  12. Wenk JF, Ge L, Zhang Z, Mojsejenko D, Potter DD, Tseng EE, Guccione JM, Ratcliffe MB. Biventricular finite element modeling of the Acorn CorCap Cardiac Support Device on a failing heart. Ann Thorac Surg. 2013 Jun; 95(6):2022-7.
  13. Lee LC, Wenk JF, Zhong L, Klepach D, Zhang Z, Ge L, Ratcliffe MB, Zohdi TI, Hsu E, Navia JL, Kassab GS, Guccione JM. Analysis of patient-specific surgical ventricular restoration: importance of an ellipsoidal left ventricular geometry for diastolic and systolic function. J Appl Physiol (1985). 2013 Jul 1; 115(1):136-44.
  14. Shimkunas R, Zhang Z, Wenk JF, Soleimani M, Khazalpour M, Acevedo-Bolton G, Wang G, Saloner D, Mishra R, Wallace AW, Ge L, Baker AJ, Guccione JM, Ratcliffe MB. Left ventricular myocardial contractility is depressed in the borderzone after posterolateral myocardial infarction. Ann Thorac Surg. 2013 May; 95(5):1619-25.
  15. Acevedo-Bolton G, Suzuki T, Malhotra D, Zhang Z, Wallace AW, Guccione JM, Saloner DA, Ratcliffe MB. Left ventricular pressure gating in ovine cardiac studies: a software-based method. J Biomech Eng. 2013 Mar 1; 135(3):34502.
  16. Ratcliffe M, Cambronero N, Ge L. Invited commentary. Ann Thorac Surg. 2013 Jan; 95(1):162.
  17. Chitsaz S, Wenk JF, Ge L, Wisneski A, Mookhoek A, Ratcliffe MB, Guccione JM, Tseng EE. Material properties of CorCap passive cardiac support device. Ann Thorac Surg. 2013 Jan; 95(1):148-54.
  18. Wenk JF, Ratcliffe MB, Guccione JM. Finite element modeling of mitral leaflet tissue using a layered shell approximation. Med Biol Eng Comput. 2012 Oct; 50(10):1071-9.
  19. Carrick R, Ge L, Lee LC, Zhang Z, Mishra R, Axel L, Guccione JM, Grossi EA, Ratcliffe MB. Patient-specific finite element-based analysis of ventricular myofiber stress after Coapsys: importance of residual stress. Ann Thorac Surg. 2012 Jun; 93(6):1964-71.
  20. Zhang Z, Sun K, Saloner DA, Wallace AW, Ge L, Baker AJ, Guccione JM, Ratcliffe MB. The benefit of enhanced contractility in the infarct borderzone: a virtual experiment. Front Physiol. 2012; 3:86.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.