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Home > Doctors > Michael J. Mann

Michael J. Mann, M.D.

Heart and lung surgeon

Dr. Michael Mann is a cardiothoracic surgeon with particular interest in coronary bypass, valve disease, aortic reconstruction, surgery for heart failure and thoracic cancer. His research interests include the development of molecular therapies for cardiothoracic disorders. While on the faculty at Harvard Medical School, he designed and directed the first clinical program for genetic manipulation during bypass surgery.

Mann earned a medical degree at the Stanford School of Medicine. He completed a residency at Stanford University Medical Center and Brigham and Women's Hospital in Boston, and a fellowship at UCSF.

Clinics

Thoracic Surgery and Oncology
1600 Divisadero St., Fourth Floor
San Francisco, CA 94143-1705
Phone: (415) 885-3882
Fax: (415) 353-9525

Hours: Monday to Friday
8 a.m. – 5 p.m.

Conditions & Treatments

More about Michael J. Mann

Additional Languages

Mandarin

Education

Stanford School of Medicine 1991

Residencies

Stanford University Medical Center 1996
Brigham and Women's Hospital 2001

Fellowships

UCSF Medical Center 2003

Selected Research and Publications

  1. Kratz JR, Tham PT, Mulvihill MS, Ziaei F, Ray MR, Hurst JW, Segal MR, Berryman DM, Chu W, He B, Jablons DM, Mann MJ. Analytical validation of a practical molecular assay prognostic of survival in nonsquamous non-small cell lung cancer. Diagn Mol Pathol. 2013 Jun; 22(2):65-9.
  2. Mann MJ, Jablons DM, Kratz JR. Prognostic assay in small, node-negative non-small cell lung cancer--reply. JAMA. 2013 Feb 27; 309(8):769-70.
  3. Yeh CC, Malhotra D, Yang YL, Xu Y, Fan Y, Li H, Mann MJ. MEK1-induced physiological hypertrophy inhibits chronic post-myocardial infarction remodeling in mice. J Cell Biochem. 2013 Jan; 114(1):47-55.
  4. Kratz JR, Van den Eeden SK, He J, Jablons DM, Mann MJ. A prognostic assay to identify patients at high risk of mortality despite small, node-negative lung tumors. JAMA. 2012 Oct 24; 308(16):1629-31.
  5. Kratz JR, He J, Van Den Eeden SK, Zhu ZH, Gao W, Pham PT, Mulvihill MS, Ziaei F, Zhang H, Su B, Zhi X, Quesenberry CP, Habel LA, Deng Q, Wang Z, Zhou J, Li H, Huang MC, Yeh CC, Segal MR, Ray MR, Jones KD, Raz DJ, Xu Z, Jahan TM, Berryman D, He B, Mann MJ, Jablons DM. A practical molecular assay to predict survival in resected non-squamous, non-small-cell lung cancer: development and international validation studies. Lancet. 2012 Mar 3; 379(9818):823-32.
  6. Wall ST, Yeh CC, Tu RY, Mann MJ, Healy KE. Biomimetic matrices for myocardial stabilization and stem cell transplantation. J Biomed Mater Res A. 2010 Dec 15; 95(4):1055-66.
  7. Yeh CC, Li H, Malhotra D, Turcato S, Nicholas S, Tu R, Zhu BQ, Cha J, Swigart PM, Myagmar BE, Baker AJ, Simpson PC, Mann MJ. Distinctive ERK and p38 signaling in remote and infarcted myocardium during post-MI remodeling in the mouse. J Cell Biochem. 2010 Apr 15; 109(6):1185-91.
  8. Wang GY, Yeh CC, Jensen BC, Mann MJ, Simpson PC, Baker AJ. Heart failure switches the RV alpha1-adrenergic inotropic response from negative to positive. Am J Physiol Heart Circ Physiol. 2010 Mar; 298(3):H913-20.
  9. Li H, Malhotra D, Yeh CC, Tu R, Zhu BQ, Birger N, Wisneski A, Cha J, Karliner JS, Mann MJ. Myocardial survival signaling in response to stem cell transplantation. J Am Coll Surg. 2009 Apr; 208(4):607-13.
  10. Yeh CC, Li H, Malhotra D, Huang MC, Zhu BQ, Goetzl EJ, Vessey DA, Karliner JS, Mann MJ. Sphingolipid signaling and treatment during remodeling of the uninfarcted ventricular wall after myocardial infarction. Am J Physiol Heart Circ Physiol. 2009 Apr; 296(4):H1193-9.
  11. Yeh CC, Malhotra D, Li H, Nicholas S, Tu R, Mann MJ. Surgical ventricular reconstruction in mice: elucidating potential targets for combined molecular/surgical intervention. J Thorac Cardiovasc Surg. 2009 Apr; 137(4):942-9.
  12. Mahimkar R, Nguyen A, Mann M, Yeh CC, Zhu BQ, Karliner JS, Lovett DH. Cardiac transgenic matrix metalloproteinase-2 expression induces myxomatous valve degeneration: a potential model of mitral valve prolapse disease. Cardiovasc Pathol. 2009 Sep-Oct; 18(5):253-61.
  13. Ratcliffe MB, Howard C, Mann M, del Nido P. National Institutes of Health funding for cardiothoracic surgical research. J Thorac Cardiovasc Surg. 2008 Aug; 136(2):392-7; discussion 398-9.
  14. Mann M, Tendulkar A, Birger N, Howard C, Ratcliffe MB. National institutes of health funding for surgical research. Ann Surg. 2008 Feb; 247(2):217-21.
  15. Mann MJ. Transcription factor decoys: a new model for disease intervention. Ann N Y Acad Sci. 2005 Nov; 1058:128-39.
  16. Mann MJ, Tseng E, Ratcliffe M, Strattman G, De Silva A, Demarco T, Achorn N, Moskalik W, Hoopes C. Use of bivalirudin, a direct thrombin inhibitor, and its reversal with modified ultrafiltration during heart transplantation in a patient with heparin-induced thrombocytopenia. J Heart Lung Transplant. 2005 Feb; 24(2):222-5.
  17. Stratmann G, deSilva AM, Tseng EE, Hambleton J, Balea M, Romo AJ, Mann MJ, Achorn NL, Moskalik WF, Hoopes CW. Reversal of direct thrombin inhibition after cardiopulmonary bypass in a patient with heparin-induced thrombocytopenia. Anesth Analg. 2004 Jun; 98(6):1635-9, table of contents.
  18. Braun-Dullaeus RC, Mann MJ, Sedding DG, Sherwood SW, von der Leyen HE, Dzau VJ. Cell cycle-dependent regulation of smooth muscle cell activation. Arterioscler Thromb Vasc Biol. 2004 May; 24(5):845-50.
  19. Mann MJ, Kramer MJ, Hall TS, Anastassiou P, Katz J, Golden J, Jones K, Jablons DM. Isolated pulmonary arteriovenous malformations requiring anatomic resection. J Thorac Cardiovasc Surg. 2004 Feb; 127(2):574-6.
  20. Mann MJ. Novel strategies for the prevention of bypass graft failure. BioDrugs. 2004; 18(1):1-8.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions by logging on to UCSF Profiles.

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