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Home > Doctors > Mitchel Berger

Mitchel Berger, M.D.

Neurosurgeon and chair of Neurological Surgery

Dr. Mitchel S. Berger, chair of Neurological Surgery, is a nationally recognized expert in treating brain and spinal cord tumors and tumor-related epilepsy in adults and children. He also is a specialist in brain mapping techniques, used to identify areas of motor, sensory and language function during surgery, and an expert in the use of the Gamma Knife for tumor treatment. He is co-director of the Adult Brain Tumor Surgery Program, director of the Brain Tumor Research Center and director of the Center for Neurological Injury and Repair.

Berger, a professor of neurosurgery at UCSF, earned a bachelor's degree from Harvard College in 1975 and a medical degree from the University of Miami School of Medicine in 1979. He completed an internship and residency at UCSF and was awarded a clinical fellowship in neuro-oncology by the American Cancer Society and a research fellowship with the Brain Tumor Research Center. He completed further fellowship training in neuro-oncology at UCSF and in pediatric neurosurgery at the Hospital for Sick Children of the University of Toronto, Canada. His professional activities include his election to the board of directors of the American Association of Neurological Surgeons and his appointment to the American Board of Neurological Surgeons. Berger is board certified in neurosurgery.

Read a Q&A with Berger.

Clinics

California Center for Pituitary Disorders
400 Parnassus Ave., Eighth Floor
San Francisco, CA 94143
Phone: (866) 559-5543

Fax: (415) 353-2939

Hours: Monday to Friday
8 a.m. – 5 p.m.

Concussion and Brain Injury Program
1500 Owens St., Second Floor
San Francisco, CA 94158
Phone: (415) 353-1915
Fax: (415) 514-6075

Hours: Monday to Friday
8 a.m. – 5 p.m.

Neuro-Oncology Clinic
400 Parnassus Ave., Eighth Floor
San Francisco, CA 94143
Phone: (415) 353-2966
Fax: (415) 353-2167

Hours: Monday to Friday
8 a.m. – 5 p.m.

Neurosurgery Clinic
400 Parnassus Ave., Eighth Floor
San Francisco, CA 94143
Phone: (415) 353-7500
Fax: (415) 353-2939

Hours: Monday to Friday
8 a.m. – 4:30 p.m.

Conditions & Treatments

More about Mitchel Berger

Education

University of Miami School of Medicine 1979

Residencies

UCSF Medical Center, General Surgery 1979

Fellowships

UCSF Medical Center, Neuro-oncology 1985
Hospital for Sick Children, Toronto, Canada, Pediatric Neurological Surgery 1986

Selected Research and Publications

  1. Safaee M, Clark AJ, Oh MC, Ivan ME, Bloch O, Kaur G, Sun MZ, Kim JM, Oh T, Berger MS, Parsa AT. Overexpression of CD97 Confers an Invasive Phenotype in Glioblastoma Cells and Is Associated with Decreased Survival of Glioblastoma Patients. PLoS One. 2013; 8(4):e62765.
  2. Shchors K, Persson AI, Rostker F, Tihan T, Lyubynska N, Li N, Swigart LB, Berger MS, Hanahan D, Weiss WA, Evan GI. Using a preclinical mouse model of high-grade astrocytoma to optimize p53 restoration therapy. Proc Natl Acad Sci U S A. 2013 Apr 16; 110(16):E1480-9.
  3. Safaee M, Clark AJ, Bloch O, Oh MC, Singh A, Auguste KI, Gupta N, McDermott MW, Aghi MK, Berger MS, Parsa AT. Surgical outcomes in choroid plexus papillomas: an institutional experience. J Neurooncol. 2013 May; 113(1):117-25.
  4. Potts MB, Berger MS. Response. J Neurosurg. 2013 Mar; 118(3):704.
  5. Rice T, Zheng S, Decker PA, Walsh KM, Bracci P, Xiao Y, McCoy LS, Smirnov I, Patoka JS, Hansen HM, Hsuang G, Wiemels JL, Tihan T, Pico AR, Prados MD, Chang SM, Berger MS, Caron A, Fink S, Kollmeyer T, Rynearson A, Voss J, Kosel ML, Fridley BL, Lachance DH, Eckel-Passow JE, Sicotte H, O'Neill BP, Giannini C, Wiencke JK, Jenkins RB, Wrensch MR. Inherited variant on chromosome 11q23 increases susceptibility to IDH-mutated but not IDH-normal gliomas regardless of grade or histology. Neuro Oncol. 2013 Feb 7.
  6. Berger MS, Carter BS. Introduction. Neurosurg Focus. 2013 Feb; 34(2):Introduction.
  7. Chen PY, Ozawa T, Drummond DC, Kalra A, Fitzgerald JB, Kirpotin DB, Wei KC, Butowski N, Prados MD, Berger MS, Forsayeth JR, Bankiewicz K, James CD. Comparing routes of delivery for nanoliposomal irinotecan shows superior anti-tumor activity of local administration in treating intracranial glioblastoma xenografts. Neuro Oncol. 2013 Feb; 15(2):189-97.
  8. Kaur G, Kane AJ, Sughrue ME, Madden M, Oh MC, Sun MZ, Safaee M, El-Sayed I, Aghi M, McDermott MW, Berger MS, Parsa AT. The prognostic implications of Hyam's subtype for patients with Kadish stage C esthesioneuroblastoma. J Clin Neurosci. 2013 Feb; 20(2):281-6.
  9. Silber J, Hashizume R, Felix T, Hariono S, Yu M, Berger MS, Huse JT, Vandenberg SR, James CD, Hodgson JG, Gupta N. Expression of miR-124 inhibits growth of medulloblastoma cells. Neuro Oncol. 2013 Jan; 15(1):83-90.
  10. Kaur G, Kane AJ, Sughrue ME, Oh M, Safaee M, Sun M, Tihan T, McDermott MW, Berger MS, Parsa AT. MIB-1 labeling index predicts recurrence in intraventricular central neurocytomas. J Clin Neurosci. 2013 Jan; 20(1):89-93.
  11. Lau CY, Greysen SR, Mistry RI, Han SJ, Mummaneni PV, Berger MS. Creating a culture of safety within operative neurosurgery: the design and implementation of a perioperative safety video. Neurosurg Focus. 2012 Nov; 33(5):E3.
  12. Tarapore PE, Martino J, Guggisberg AG, Owen J, Honma SM, Findlay A, Berger MS, Kirsch HE, Nagarajan SS. Magnetoencephalographic imaging of resting-state functional connectivity predicts postsurgical neurological outcome in brain gliomas. Neurosurgery. 2012 Nov; 71(5):1012-22.
  13. Bloch O, Han SJ, Cha S, Sun MZ, Aghi MK, McDermott MW, Berger MS, Parsa AT. Impact of extent of resection for recurrent glioblastoma on overall survival. J Neurosurg. 2012 Dec; 117(6):1032-8.
  14. Garvin JH, Selch MT, Holmes E, Berger MS, Finlay JL, Flannery A, Goldwein JW, Packer RJ, Rorke-Adams LB, Shiminski-Maher T, Sposto R, Stanley P, Tannous R, Pollack IF. Phase II study of pre-irradiation chemotherapy for childhood intracranial ependymoma. Children's Cancer Group protocol 9942: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2012 Dec 15; 59(7):1183-9.
  15. Jenkins RB, Xiao Y, Sicotte H, Decker PA, Kollmeyer TM, Hansen HM, Kosel ML, Zheng S, Walsh KM, Rice T, Bracci P, McCoy LS, Smirnov I, Patoka JS, Hsuang G, Wiemels JL, Tihan T, Pico AR, Prados MD, Chang SM, Berger MS, Caron AA, Fink SR, Halder C, Rynearson AL, Fridley BL, Buckner JC, O'Neill BP, Giannini C, Lachance DH, Wiencke JK, Eckel-Passow JE, Wrensch MR. A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation. Nat Genet. 2012 Oct; 44(10):1122-5.
  16. Engler JR, Robinson AE, Smirnov I, Hodgson JG, Berger MS, Gupta N, James CD, Molinaro A, Phillips JJ. Increased microglia/macrophage gene expression in a subset of adult and pediatric astrocytomas. PLoS One. 2012; 7(8):e43339.
  17. Crane CA, Han SJ, Ahn B, Oehlke J, Kivett V, Fedoroff A, Butowski N, Chang SM, Clarke J, Berger MS, McDermott MW, Prados MD, Parsa AT. Individual Patient-Specific Immunity against High-Grade Glioma after Vaccination with Autologous Tumor Derived Peptides Bound to the 96 KD Chaperone Protein. Clin Cancer Res. 2013 Jan 1; 19(1):205-14.
  18. Felicella MM, Hagenkord JM, Kash SF, Powers MP, Berger MS, Perry A. A common 8q (MYC) amplification detected in a multifocal anaplastic astrocytoma by SNP array karyotyping. Clin Neuropathol. 2012 Jul-Aug; 31(4):210-5.
  19. Mueller S, Phillips J, Onar-Thomas A, Romero E, Zheng S, Wiencke JK, McBride SM, Cowdrey C, Prados MD, Weiss WA, Berger MS, Gupta N, Haas-Kogan DA. PTEN promoter methylation and activation of the PI3K/Akt/mTOR pathway in pediatric gliomas and influence on clinical outcome. Neuro Oncol. 2012 Sep; 14(9):1146-52.
  20. Abazov VM, Abbott B, Acharya BS, Adams M, Adams T, Alexeev GD, Alkhazov G, Alton A, Alverson G, Aoki M, Askew A, Atkins S, Augsten K, Avila C, Badaud F, Bagby L, Baldin B, Bandurin DV, Banerjee S, Barberis E, Baringer P, Barreto J, Bartlett JF, Bassler U, Bazterra V, Bean A, Begalli M, Bellantoni L, Berger MS, Beri SB, Bernardi G, Bernhard R, Bertram I, Besançon M, Beuselinck R, Bezzubov VA, Bhat PC, Bhatia S, Bhatnagar V, Blazey G, Blessing S, Bloom K, Boehnlein A, Boline D, Boos EE, Borissov G, Bose T, Brandt A, Brandt O, Brock R, Brooijmans G, Bross A, Brown D, Brown J, Bu XB, Buehler M, Buescher V, Bunichev V, Burdin S, Buszello CP, Camacho-Pérez E, Casey BC, Castilla-Valdez H, Caughron S, Chakrabarti S, Chakraborty D, Chan KM, Chandra A, Chapon E, Chen G, Chevalier-Théry S, Cho DK, Cho SW, Choi S, Choudhary B, Cihangir S, Claes D, Clutter J, Cooke M, Cooper WE, Corcoran M, Couderc F, Cousinou MC, Croc A, Cutts D, Das A, Davies G, de Jong SJ, De la Cruz-Burelo E, Déliot F, Demina R, Denisov D, Denisov SP, Desai S, Deterre C, DeVaughan K, Diehl HT, Diesburg M, Ding PF, Dominguez A, Dubey A, Dudko LV, Duggan D, Duperrin A, Dutt S, Dyshkant A, Eads M, Edmunds D, Ellison J, Elvira VD, Enari Y, Evans H, Evdokimov A, Evdokimov VN, Facini G, Feng L, Ferbel T, Fiedler F, Filthaut F, Fisher W, Fisk HE, Fortner M, Fox H, Fuess S, Garcia-Bellido A, García-González JA, García-Guerra GA, Gavrilov V, Gay P, Geng W, Gerbaudo D, Gerber CE, Gershtein Y, Ginther G, Golovanov G, Goussiou A, Grannis PD, Greder S, Greenlee H, Grenier G, Gris P, Grivaz JF, Grohsjean A, Grünendahl S, Grünewald MW, Guillemin T, Gutierrez G, Gutierrez P, Haas A, Hagopian S, Haley J, Han L, Harder K, Harel A, Hauptman JM, Hays J, Head T, Hebbeker T, Hedin D, Hegab H, Heinson AP, Heintz U, Hensel C, Heredia-De la Cruz I, Herner K, Hesketh G, Hildreth MD, Hirosky R, Hoang T, Hobbs JD, Hoeneisen B, Hohlfeld M, Howley I, Hubacek Z, Hynek V, Iashvili I, Ilchenko Y, Illingworth R, Ito AS, Jabeen S, Jaffré M, Jayasinghe A, Jesik R, Johns K, Johnson E, Johnson M, Jonckheere A, Jonsson P, Joshi J, Jung AW, Juste A, Kaadze K, Kajfasz E, Karmanov D, Kasper PA, Katsanos I, Kehoe R, Kermiche S, Khalatyan N, Khanov A, Kharchilava A, Kharzheev YN, Kiselevich I, Kohli JM, Kostelecký VA, Kozelov AV, Kraus J, Kulikov S, Kumar A, Kupco A, Kurca T, Kuzmin VA, Lammers S, Landsberg G, Lebrun P, Lee HS, Lee SW, Lee WM, Lellouch J, Li H, Li L, Li QZ, Lim JK, Lincoln D, Linnemann J, Lipaev VV, Lipton R, Liu H, Liu Y, Lobodenko A, Lokajicek M, Lopes de Sa R, Lubatti HJ, Luna-Garcia R, Lyon AL, Maciel AK, Madar R, Magaña-Villalba R, Malik S, Malyshev VL, Maravin Y, Martínez-Ortega J, McCarthy R, McGivern CL, Meijer MM, Melnitchouk A, Menezes D, Mercadante PG, Merkin M, Meyer A, Meyer J, Miconi F, Mondal NK, Mulhearn M, Nagy E, Naimuddin M, Narain M, Nayyar R, Neal HA, Negret JP, Neustroev P, Nunnemann T, Obrant G, Orduna J, Osman N, Osta J, Padilla M, Pal A, Parashar N, Parihar V, Park SK, Partridge R, Parua N, Patwa A, Penning B, Perfilov M, Peters Y, Petridis K, Petrillo G, Pétroff P, Pleier MA, Podesta-Lerma PL, Podstavkov VM, Popov AV, Prewitt M, Price D, Prokopenko N, Qian J, Quadt A, Quinn B, Rangel MS, Ranjan K, Ratoff PN, Razumov I, Renkel P, Ripp-Baudot I, Rizatdinova F, Rominsky M, Ross A, Royon C, Rubinov P, Ruchti R, Sajot G, Salcido P, Sánchez-Hernández A, Sanders MP, Sanghi B, Santos AS, Savage G, Sawyer L, Scanlon T, Schamberger RD, Scheglov Y, Schellman H, Schlobohm S, Schwanenberger C, Schwienhorst R, Sekaric J, Severini H, Shabalina E, Shary V, Shaw S, Shchukin AA, Shivpuri RK, Simak V, Skubic P, Slattery P, Smirnov D, Smith KJ, Snow GR, Snow J, Snyder S, Söldner-Rembold S, Sonnenschein L, Soustruznik K, Stark J, Stoyanova DA, Strauss M, Stutte L, Suter L, Svoisky P, Takahashi M, Titov M, Tokmenin VV, Tsai YT, Tschann-Grimm K, Tsybychev D, Tuchming B, Tully C, Uvarov L, Uvarov S, Uzunyan S, Van Kooten R, van Leeuwen WM, Varelas N, Varnes EW, Vasilyev IA, et al. Search for violation of Lorentz invariance in top quark pair production and decay. Phys Rev Lett. 2012 Jun 29; 108(26):261603.

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