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Randall Lee, Ph.D., M.D.

Cardiologist and electrophysiologist

Dr. Randall J. Lee graduated from UCLA Medical School in 1984 where he also obtained his doctorate in pharmacology. After completing an internal medicine residency at Harbor-UCLA Medical Center in Torrance, Calif., he completed a cardiology fellowship and postdoctoral fellowship in biochemistry and molecular biology at Stanford University, where he earned a Physician Scientist Award and the Upjohn Young Investigator Award in cardiology. Lee subspecialized in cardiac electrophysiology during his second fellowship at UCSF.

His research focuses on cellular and molecular aspects of cardiac arrhythmias and vascular regeneration. He is investigating the cellular and molecular derangements that occur during cardiac arrhythmias and myocardial infarctions. Lee uses genetic engineering techniques to investigate derangements during cardiac arrhythmias and myocardial infarctions and as possible therapeutic tools. Lee also is interested in cardiac development of the conduction system and the means to alter conduction, which then may be applied to diseased states.

Clinics

Asian Heart and Vascular Center
1600 Divisadero St., Second Floor, Suite C-244
San Francisco, CA 94115
Appointments: (415) 885-3678
Events: (415) 885-3678
Fax: (415) 885-3676

Cardiac Electrophysiology and Arrhythmia Service
400 Parnassus Ave., Floor B1, Room 094
San Francisco, CA 94143
Phone: (415) 353-2554
Fax: (415) 353-2528

Hours: Monday to Friday
8 a.m. – 5 p.m.

Cardiovascular Genetics Program
400 Parnassus Avenue, Plaza Level, Room 94
San Francisco, CA 94143
Phone: (415) 353-2873
Fax: (415) 476-5355

Hours: Monday
noon – 4 p.m

Conditions & Treatments

More about Randall Lee

Education

UCLA School of Medicine 1984

Residencies

Harbor-UCLA Medical Center, Internal Medicine 1988

Fellowships

Stanford University Medical Center, Cardiovascular Diseases 1991

Selected Research and Publications

  1. Lee RJ. Evolution of stroke prevention in nonvalvular atrial fibrillation patients. J Am Coll Cardiol. 2014 Jul 8; 64(1):13-5.
  2. Stepanyan G, Badhwar N, Lee RJ, Marcus GM, Lee BK, Tseng ZH, Vedantham V, Olgin J, Scheinman M, Gerstenfeld EP. Safety of new oral anticoagulants for patients undergoing atrial fibrillation ablation. J Interv Card Electrophysiol. 2014 Jun; 40(1):33-8.
  3. Koneru JN, Badhwar N, Ellenbogen KA, Lee RJ. LAA ligation using the LARIAT suture delivery device: Tips and tricks for a successful procedure. Heart Rhythm. 2014 May; 11(5):911-21.
  4. Han FT, Bartus K, Lakkireddy D, Rojas F, Bednarek J, Kapelak B, Bartus M, Sadowski J, Badhwar N, Earnest M, Valderrabano M, Lee RJ. The effects of LAA ligation on LAA electrical activity. Heart Rhythm. 2014 May; 11(5):864-70.
  5. Boyle AJ, Hwang J, Ye J, Shih H, Jun K, Zhang Y, Fang Q, Sievers R, Yeghiazarians Y, Lee RJ. The effects of aging on apoptosis following myocardial infarction. Cardiovasc Ther. 2013 Dec; 31(6):e102-10.
  6. Hsu JC, Badhwar N, Gerstenfeld EP, Lee RJ, Mandyam MC, Dewland TA, Imburgia KE, Hoffmayer KS, Vedantham V, Lee BK, Tseng ZH, Scheinman MM, Olgin JE, Marcus GM. Randomized trial of conventional transseptal needle versus radiofrequency energy needle puncture for left atrial access (the TRAVERSE-LA study). J Am Heart Assoc. 2013 Oct; 2(5):e000428.
  7. Mihardja SS, Gonzales JA, Gao D, Sievers RE, Fang Q, Stillson CA, Yu J, Peng M, Lee RJ. The effect of a peptide-modified thermo-reversible methylcellulose on wound healing and LV function in a chronic myocardial infarction rodent model. Biomaterials. 2013 Nov; 34(35):8869-77.
  8. Hashem SI, Lam ML, Mihardja SS, White SM, Lee RJ, Claycomb WC. Shox2 regulates the pacemaker gene program in embryoid bodies. Stem Cells Dev. 2013 Nov 1; 22(21):2915-26.
  9. Sabbah HN, Wang M, Gupta RC, Rastogi S, Ilsar I, Sabbah MS, Kohli S, Helgerson S, Lee RJ. Augmentation of left ventricular wall thickness with alginate hydrogel implants improves left ventricular function and prevents progressive remodeling in dogs with chronic heart failure. JACC Heart Fail. 2013 Jun; 1(3):252-8.
  10. Fang Q, Mok PY, Thomas AE, Haddad DJ, Saini SA, Clifford BT, Kapasi NK, Danforth OM, Usui M, Ye W, Luu E, Sharma R, Bartel MJ, Pathmanabhan JA, Ang AA, Sievers RE, Lee RJ, Springer ML. Pleiotrophin gene therapy for peripheral ischemia: evaluation of full-length and truncated gene variants. PLoS One. 2013; 8(4):e61413.
  11. Lee LC, Wall ST, Klepach D, Ge L, Zhang Z, Lee RJ, Hinson A, Gorman JH, Gorman RC, Guccione JM. Algisyl-LVR™ with coronary artery bypass grafting reduces left ventricular wall stress and improves function in the failing human heart. Int J Cardiol. 2013 Oct 3; 168(3):2022-8.
  12. Bartus K, Han FT, Bednarek J, Myc J, Kapelak B, Sadowski J, Lelakowski J, Bartus S, Yakubov SJ, Lee RJ. Percutaneous left atrial appendage suture ligation using the LARIAT device in patients with atrial fibrillation: initial clinical experience. J Am Coll Cardiol. 2013 Jul 9; 62(2):108-18.
  13. Mihardja SS, Lee RJ. Using extracellular matrix-derived peptides to alter the microenvironment for myocardial repair. Curr Vasc Pharmacol. 2012 May; 10(3):342-6.
  14. Mandyam MC, Vedantham V, Scheinman MM, Tseng ZH, Badhwar N, Lee BK, Lee RJ, Gerstenfeld EP, Olgin JE, Marcus GM. Alcohol and vagal tone as triggers for paroxysmal atrial fibrillation. Am J Cardiol. 2012 Aug 1; 110(3):364-8.
  15. Lee RJ, Hinson A, Helgerson S, Bauernschmitt R, Sabbah HN. Polymer-based restoration of left ventricular mechanics. Cell Transplant. 2013; 22(3):529-33.
  16. Hsu JC, Friday J, Lee BK, Azadani PN, Lee RJ, Badhwar N, Tseng ZH, Olgin JE, Marcus GM. Predictors of axillary vein location for vascular access during pacemaker and defibrillator lead implantation. Pacing Clin Electrophysiol. 2011 Dec; 34(12):1585-92.
  17. Hoffmayer KS, Yang Y, Joseph S, McCabe JM, Bhave P, Hsu J, Ng RK, Lee BK, Badhwar N, Lee RJ, Tseng ZH, Olgin JE, Narayan SM, Marcus GM, Scheinman MM. Predictors of unusual ECG characteristics in cavotricuspid isthmus-dependent atrial flutter ablation. Pacing Clin Electrophysiol. 2011 Oct; 34(10):1251-7.
  18. Iwai S, Badhwar N, Markowitz SM, Stambler BS, Keung E, Lee RJ, Chung JH, Olgin JE, Scheinman MM, Lerman BB. Electrophysiologic properties of para-Hisian atrial tachycardia. Heart Rhythm. 2011 Aug; 8(8):1245-53.
  19. Mihardja SS, Yu J, Lee RJ. Extracellular matrix-derived peptides and myocardial repair. Cell Adh Migr. 2011 Mar-Apr; 5(2):111-3.
  20. Shih H, Lee B, Lee RJ, Boyle AJ. The aging heart and post-infarction left ventricular remodeling. J Am Coll Cardiol. 2011 Jan 4; 57(1):9-17.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.