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Robin M. Shaw, M.D.

Cardiologist

Dr. Robin Shaw is a cardiologist specializing in acute-care cardiology, coronary artery disease and general cardiology. He has a special interest in the genetics and non-invasive management of cardiac arrhythmias, or irregular heartbeats. In addition to caring for patients, Shaw researches the cellular biology of the heart muscle and the basic mechanisms of heart failure and cardiac arrhythmias. His goal is to use insights from these studies to develop new therapies for heart disease. Shaw's research is funded by the National Institutes of Health and the American Heart Association.

Shaw is the author of numerous scientific articles and reviews, as well as the World Book Encyclopedia's sections on cardiovascular circulation and heart failure. Shaw is an assistant professor of medicine at UCSF, and a member of the American Heart Association and the American Society for Cell Biology. Shaw received his medical degree and a Ph.D. in Biomedical Engineering from Case Western Reserve University.

Clinics

Cardiovascular Care and Prevention Center at Mission Bay
535 Mission Bay Blvd. South
San Francisco, CA 94158
Phone: (415) 353-2873
Fax: (415) 353-2528

Hours: Monday to Friday
8 a.m. – 5 p.m.

Cardiovascular Genetics Program
400 Parnassus Avenue, Plaza Level, Room 94
San Francisco, CA 94143
Phone: (415) 353-2873
Fax: (415) 476-5355

Hours: Monday
noon – 4 p.m

Heart Transplant Program
400 Parnassus Ave., Sixth Floor
San Francisco, CA 94143
Phone: (415) 353-4145
Fax: (415) 353-4166

Hours: Thursday 8 a.m. – 5 p.m. (times vary depending on the number of doctors in clinic)

Conditions & Treatments

More about Robin M. Shaw

Education

Case Western Reserve School of Medicine 1999

Residencies

UCSF Medical Center 2001

Fellowships

UCSF Medical Center, Cardiology 2004

Selected Research and Publications

  1. Gao D, Zhang L, Dhillon R, Hong TT, Shaw RM, Zhu J. Dynasore protects mitochondria and improves cardiac lusitropy in langendorff perfused mouse heart. PLoS One. 2013; 8(4):e60967.
  2. Shaw RM, Colecraft HM. L-type calcium channel targeting and local signalling in cardiac myocytes. Cardiovasc Res. 2013 May 1; 98(2):177-86.
  3. Shaw RM. Reduced sodium channels in human ARVC. Heart Rhythm. 2013 Mar; 10(3):420-1.
  4. Zhang SS, Shaw RM. Multilayered regulation of cardiac ion channels. Biochim Biophys Acta. 2013 Apr; 1833(4):876-85.
  5. Smyth JW, Vogan JM, Buch PJ, Zhang SS, Fong TS, Hong TT, Shaw RM. Actin cytoskeleton rest stops regulate anterograde traffic of connexin 43 vesicles to the plasma membrane. Circ Res. 2012 Mar 30; 110(7):978-89.
  6. Hong TT, Cogswell R, James CA, Kang G, Pullinger CR, Malloy MJ, Kane JP, Wojciak J, Calkins H, Scheinman MM, Tseng ZH, Ganz P, De Marco T, Judge DP, Shaw RM. Plasma BIN1 correlates with heart failure and predicts arrhythmia in patients with arrhythmogenic right ventricular cardiomyopathy. Heart Rhythm. 2012 Jun; 9(6):961-7.
  7. Smyth JW, Shaw RM. Visualizing cardiac ion channel trafficking pathways. Methods Enzymol. 2012; 505:187-202.
  8. Hong TT, Smyth JW, Chu KY, Vogan JM, Fong TS, Jensen BC, Fang K, Halushka MK, Russell SD, Colecraft H, Hoopes CW, Ocorr K, Chi NC, Shaw RM. BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes. Heart Rhythm. 2012 May; 9(5):812-20.
  9. Zhang SS, Kim KH, Rosen A, Smyth JW, Sakuma R, Delgado-Olguín P, Davis M, Chi NC, Puviindran V, Gaborit N, Sukonnik T, Wylie JN, Brand-Arzamendi K, Farman GP, Kim J, Rose RA, Marsden PA, Zhu Y, Zhou YQ, Miquerol L, Henkelman RM, Stainier DY, Shaw RM, Hui CC, Bruneau BG, Backx PH. Iroquois homeobox gene 3 establishes fast conduction in the cardiac His-Purkinje network. Proc Natl Acad Sci U S A. 2011 Aug 16; 108(33):13576-81.
  10. Smyth JW, Shaw RM. The gap junction life cycle. Heart Rhythm. 2012 Jan; 9(1):151-3.
  11. Chi NC, Bussen M, Brand-Arzamendi K, Ding C, Olgin JE, Shaw RM, Martin GR, Stainier DY. Cardiac conduction is required to preserve cardiac chamber morphology. Proc Natl Acad Sci U S A. 2010 Aug 17; 107(33):14662-7.
  12. Smyth JW, Shaw RM. Forward trafficking of ion channels: what the clinician needs to know. Heart Rhythm. 2010 Aug; 7(8):1135-40.
  13. Hong TT, Smyth JW, Gao D, Chu KY, Vogan JM, Fong TS, Jensen BC, Colecraft HM, Shaw RM. BIN1 localizes the L-type calcium channel to cardiac T-tubules. PLoS Biol. 2010 Feb; 8(2):e1000312.
  14. Smyth JW, Hong TT, Gao D, Vogan JM, Jensen BC, Fong TS, Simpson PC, Stainier DY, Chi NC, Shaw RM. Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium. J Clin Invest. 2010 Jan; 120(1):266-79.
  15. Ieda M, Tsuchihashi T, Ivey KN, Ross RS, Hong TT, Shaw RM, Srivastava D. Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling. Dev Cell. 2009 Feb; 16(2):233-44.
  16. Chi NC, Shaw RM, Jungblut B, Huisken J, Ferrer T, Arnaout R, Scott I, Beis D, Xiao T, Baier H, Jan LY, Tristani-Firouzi M, Stainier DY. Genetic and physiologic dissection of the vertebrate cardiac conduction system. PLoS Biol. 2008 May 13; 6(5):e109.
  17. Saxena A, Fish JE, White MD, Yu S, Smyth JW, Shaw RM, DiMaio JM, Srivastava D. Stromal cell-derived factor-1alpha is cardioprotective after myocardial infarction. Circulation. 2008 Apr 29; 117(17):2224-31.
  18. Chi NC, Shaw RM, De Val S, Kang G, Jan LY, Black BL, Stainier DY. Foxn4 directly regulates tbx2b expression and atrioventricular canal formation. Genes Dev. 2008 Mar 15; 22(6):734-9.
  19. Smyth JW, Shaw RM. Visualizing ion channel dynamics at the plasma membrane. Heart Rhythm. 2008 Jun; 5(6 Suppl):S7-11.
  20. Shaw RM, Fay AJ, Puthenveedu MA, von Zastrow M, Jan YN, Jan LY. Microtubule plus-end-tracking proteins target gap junctions directly from the cell interior to adherens junctions. Cell. 2007 Feb 9; 128(3):547-60.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions by logging on to UCSF Profiles.