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Ronald Clyman, M.D.

Neonatologist

Dr. Ronald Clyman is a neonatologist and an expert in the treatment of extremely premature infants. He is internationally renowned for his basic and clinical studies of the ductus arteriousus, a blood vessel that transports blood from the right side of the heart to the aorta, which is the large blood vessel that distributes blood to a baby's body while still in the womb. He has helped define the role of oxygen and prostaglandins in ductus patency and is currently studying the mechanisms leading to irreversible ductal closure. Clyman is a professor of pediatrics at the University of California, San Francisco and a member of the Cardiovascular Research Institute. He earned his medical degree at Columbia University and is board certified in pediatrics and neonatal and perinatal medicine.

More about Ronald Clyman

Education

Columbia University School of Medicine 1971

Selected Research and Publications

  1. Clyman RI, Wickremasinghe A, Merritt TA, Solomon T, McNamara P, Jain A, Singh J, Chu A, Noori S, Sekar K, Lavoie PM, Attridge JT, Swanson JR, Gillam-Krakauer M, Reese J, DeMauro S, Poindexter B, Aucott S, Satpute M, Fernandez E, Auchus RJ. Hypotension following Patent Ductus Arteriosus Ligation: The Role of Adrenal Hormones. J Pediatr. 2014 Jun; 164(6):1449-1455.e1.
  2. Jelin AC, Kuppermann M, Erickson K, Clyman R, Schulkin J. Obstetricians' attitudes and beliefs regarding umbilical cord clamping. J Matern Fetal Neonatal Med. 2014 Sep; 27(14):1457-61.
  3. Yanowitz TD, Reese J, Gillam-Krakauer M, Cochran CM, Jegatheesan P, Lau J, Tran VT, Walsh M, Carey WA, Fujii A, Fabio A, Clyman R. Superior Mesenteric Artery Blood Flow Velocities following Medical Treatment of a Patent Ductus Arteriosus. J Pediatr. 2014 Mar; 164(3):661-3.
  4. Clyman RI. The role of patent ductus arteriosus and its treatments in the development of bronchopulmonary dysplasia. Semin Perinatol. 2013 Apr; 37(2):102-7.
  5. Clyman R, Wickremasinghe A, Jhaveri N, Hassinger DC, Attridge JT, Sanocka U, Polin R, Gillam-Krakauer M, Reese J, Mammel M, Couser R, Mulrooney N, Yanowitz TD, Derrick M, Jegatheesan P, Walsh M, Fujii A, Porta N, Carey WA, Swanson JR. Enteral feeding during indomethacin and ibuprofen treatment of a patent ductus arteriosus. J Pediatr. 2013 Aug; 163(2):406-11.
  6. Catenacci M, Miyagi S, Wickremasinghe AC, Lucas SS, de Alba Campomanes AG, Good WV, Clyman RI. Dopamine-resistant hypotension and severe retinopathy of prematurity. J Pediatr. 2013 Aug; 163(2):400-5.
  7. Clyman RI. Surgical ligation of the patent ductus arteriosus: treatment or morbidity? J Pediatr. 2012 Oct; 161(4):583-4.
  8. Wickremasinghe AC, Rogers EE, Piecuch RE, Johnson BC, Golden S, Moon-Grady AJ, Clyman RI. Neurodevelopmental outcomes following two different treatment approaches (early ligation and selective ligation) for patent ductus arteriosus. J Pediatr. 2012 Dec; 161(6):1065-72.
  9. Clyman RI, Couto J, Murphy GM. Patent ductus arteriosus: are current neonatal treatment options better or worse than no treatment at all? Semin Perinatol. 2012 Apr; 36(2):123-9.
  10. Sutherland MR, Yoder BA, McCurnin D, Seidner S, Gubhaju L, Clyman RI, Black MJ. Effects of ibuprofen treatment on the developing preterm baboon kidney. Am J Physiol Renal Physiol. 2012 May 15; 302(10):F1286-92.
  11. Waleh N, Seidner S, McCurnin D, Giavedoni L, Hodara V, Goelz S, Liu BM, Roman C, Clyman RI. Anatomic closure of the premature patent ductus arteriosus: The role of CD14+/CD163+ mononuclear cells and VEGF in neointimal mound formation. Pediatr Res. 2011 Oct; 70(4):332-8.
  12. Waleh N, McCurnin DC, Yoder BA, Shaul PW, Clyman RI. Patent ductus arteriosus ligation alters pulmonary gene expression in preterm baboons. Pediatr Res. 2011 Mar; 69(3):212-6.
  13. Shah NA, Hills NK, Waleh N, McCurnin D, Seidner S, Chemtob S, Clyman R. Relationship between circulating platelet counts and ductus arteriosus patency after indomethacin treatment. J Pediatr. 2011 Jun; 158(6):919-923.e1-2.
  14. Loeliger M, Shields A, McCurnin D, Clyman RI, Yoder B, Inder TE, Rees SM. Ibuprofen treatment for closure of patent ductus arteriosus is not associated with increased risk of neuropathology. Pediatr Res. 2010 Oct; 68(4):298-302.
  15. Waleh N, Hodnick R, Jhaveri N, McConaghy S, Dagle J, Seidner S, McCurnin D, Murray JC, Ohls R, Clyman RI. Patterns of gene expression in the ductus arteriosus are related to environmental and genetic risk factors for persistent ductus patency. Pediatr Res. 2010 Oct; 68(4):292-7.
  16. Jhaveri N, Moon-Grady A, Clyman RI. Early surgical ligation versus a conservative approach for management of patent ductus arteriosus that fails to close after indomethacin treatment. J Pediatr. 2010 Sep; 157(3):381-7, 387.e1.
  17. Chen S, Tacy T, Clyman R. How useful are B-type natriuretic peptide measurements for monitoring changes in patent ductus arteriosus shunt magnitude? J Perinatol. 2010 Dec; 30(12):780-5.
  18. Jhaveri N, Soll RF, Clyman RI. Feeding practices and patent ductus arteriosus ligation preferences-are they related? Am J Perinatol. 2010 Sep; 27(8):667-74.
  19. Clyman R, Chemtob S. Vessel remodeling in the newborn: platelets fill the gap. Nat Med. 2010 Jan; 16(1):33-5.
  20. Reese J, Waleh N, Poole SD, Brown N, Roman C, Clyman RI. Chronic in utero cyclooxygenase inhibition alters PGE2-regulated ductus arteriosus contractile pathways and prevents postnatal closure. Pediatr Res. 2009 Aug; 66(2):155-61.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.