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Ruby Ghadially, M.D.

Dermatologist

Clinics

Dermatology Clinic
1701 Divisadero St., Third and Fourth Floors
San Francisco, CA 94115
Phone: (415) 353–7800
Fax: (415) 353–7870

Hours: Monday to Friday, 8 a.m. – 5 p.m.

Conditions & Treatments

More about Ruby Ghadially

Additional Languages

French

Education

University of Sheffield England 1982

Residencies

University of Toronto, Dermatology 1988

Selected Research and Publications

  1. Szabo AZ, Fong S, Yue L, Zhang K, Strachan LR, Scalapino K, Mancianti ML, Ghadially R. The CD44+ ALDH+ population of human keratinocytes is enriched for epidermal stem cells with long-term repopulating ability. Stem Cells. 2013 Apr; 31(4):786-99.
  2. Charruyer A, Strachan LR, Yue L, Toth AS, Cecchini G, Mancianti ML, Ghadially R. CD133 is a marker for long-term repopulating murine epidermal stem cells. J Invest Dermatol. 2012 Nov; 132(11):2522-33.
  3. Ghadially R. 25 years of epidermal stem cell research. J Invest Dermatol. 2012 Mar; 132(3 Pt 2):797-810.
  4. Ghadially R. The role of stem and circulating cells in cancer metastasis. J Surg Oncol. 2011 May 1; 103(6):555-7.
  5. Charruyer A, Ghadially R. What's new in dermatology: epidermal stem cells. G Ital Dermatol Venereol. 2011 Feb; 146(1):57-67.
  6. Boonyaratanakornkit JB, Yue L, Strachan LR, Scalapino KJ, LeBoit PE, Lu Y, Leong SP, Smith JE, Ghadially R. Selection of tumorigenic melanoma cells using ALDH. J Invest Dermatol. 2010 Dec; 130(12):2799-808.
  7. Strachan LR, Ghadially R. Limiting dilution analysis of murine epidermal stem cells using an in vivo regeneration assay. Methods Mol Biol. 2010; 585:421-32.
  8. Charruyer A, Barland CO, Yue L, Wessendorf HB, Lu Y, Lawrence HJ, Mancianti ML, Ghadially R. Transit-amplifying cell frequency and cell cycle kinetics are altered in aged epidermis. J Invest Dermatol. 2009 Nov; 129(11):2574-83.
  9. Charruyer A, Ghadially R. Stem cells and tissue-engineered skin. Skin Pharmacol Physiol. 2009; 22(2):55-62.
  10. Strachan LR, Ghadially R. Tiers of clonal organization in the epidermis: the epidermal proliferation unit revisited. Stem Cell Rev. 2008 Sep; 4(3):149-57.
  11. Strachan LR, Scalapino KJ, Lawrence HJ, Ghadially R. Rapid adhesion to collagen isolates murine keratinocytes with limited long-term repopulating ability in vivo despite high clonogenicity in vitro. Stem Cells. 2008 Jan; 26(1):235-43.
  12. Silvander M, Ringstad L, Ghadially R, Sk├Âld T. A new water-based topical carrier with polar skin-lipids. Lipids Health Dis. 2006; 5:12.
  13. Ghadially R. Epidermal stem cells. Adv Dermatol. 2005; 21:335-55.
  14. Ghadially R. In search of the elusive epidermal stem cell. Ernst Schering Res Found Workshop. 2005; (54):45-62.
  15. Barland CO, Zettersten E, Brown BS, Ye J, Elias PM, Ghadially R. Imiquimod-induced interleukin-1 alpha stimulation improves barrier homeostasis in aged murine epidermis. J Invest Dermatol. 2004 Feb; 122(2):330-6.
  16. Schneider TE, Barland C, Alex AM, Mancianti ML, Lu Y, Cleaver JE, Lawrence HJ, Ghadially R. Measuring stem cell frequency in epidermis: a quantitative in vivo functional assay for long-term repopulating cells. Proc Natl Acad Sci U S A. 2003 Sep 30; 100(20):11412-7.
  17. Ye J, Garg A, Calhoun C, Feingold KR, Elias PM, Ghadially R. Alterations in cytokine regulation in aged epidermis: implications for permeability barrier homeostasis and inflammation. I. IL-1 gene family. Exp Dermatol. 2002 Jun; 11(3):209-16.
  18. Elias PM, Ghadially R. The aged epidermal permeability barrier: basis for functional abnormalities. Clin Geriatr Med. 2002 Feb; 18(1):103-20, vii.
  19. Kao JS, Garg A, Mao-Qiang M, Crumrine D, Ghadially R, Feingold KR, Elias PM. Testosterone perturbs epidermal permeability barrier homeostasis. J Invest Dermatol. 2001 Mar; 116(3):443-51.
  20. Zettersten E, Man MQ, Sato J, Denda M, Farrell A, Ghadially R, Williams ML, Feingold KR, Elias PM. Recessive x-linked ichthyosis: role of cholesterol-sulfate accumulation in the barrier abnormality. J Invest Dermatol. 1998 Nov; 111(5):784-90.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.