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Stephen Hauser, M.D.

Neurologist and immunologist

Dr. Stephen Hauser is chair of Neurology at UCSF and a leader in the international effort to identify genetic causes of multiple sclerosis (MS). He is the first physician-researcher to demonstrate a promising weapon against progressive MS. He identified the benefit of immunosuppression that prevents the body's immune system from attacking the myelin sheath, the insulation that surrounds the nerves in the brain and spinal cord.

Hauser joined UCSF in 1992 as chair of Neurology. He is a graduate of the Massachusetts Institute of Technology and Harvard Medical School. He trained in internal medicine at New York Hospital-Cornell Medical Center, in neurology at Massachusetts General Hospital and in immunology at Harvard Medical School and Institute Pasteur in Paris. He is a fellow of the American Academy of the Arts and Sciences and American Association of Physicians, and a member of the Institute of Medicine of the National Academy of Sciences, a former president of the American Neurological Association and an editor of the textbook, "Harrison's Principles of Internal Medicine." He is the Robert A. Fishman Distinguished Professor of Neurology in the UCSF School of Medicine.


Multiple Sclerosis Center
1500 Owens St., Suite 320
San Francisco, CA 94158
Phone: (415) 353-2069
Fax: (415) 353-2633

Hours: Monday to Friday
8:30 a.m. – 4:30 p.m.

Neurology Clinic
400 Parnassus Ave., Eighth Floor
San Francisco, CA 94143
Phone: (415) 353-2273
Fax: (415) 353-2898

Hours: Monday to Friday
8:30 a.m. – 4:30 p.m.

Conditions & Treatments

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Harvard University School of Medicine 1975


Massachusetts General Hospital, Internal Medicine 1978


Massachusetts General Hospital, Neurology 1980

Selected Research and Publications

  1. Johnston SC, Ferriero DM, Josephson SA, Lowenstein DH, Messing RO, Oksenberg J, Stewart A, Hauser SL. Have the Annals editors added value? Ann Neurol. 2013 Nov; 74(5):A7-9.
  2. Hauser SL, Josephson SA, Johnston SC. Reviewing how we review. Ann Neurol. 2013 Oct; 74(4):A5-A25.
  3. Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet. 2013 Nov; 45(11):1353-60.
  4. Brown RH, Hauser SL. Introduction to a special edition of Annals: Therapeutic prospects. Ann Neurol. 2013 Sep; 74(3):A15.
  5. Josephson SA, Johnston SC, Hauser SL. Blockbusters for cheap? The difficulties surrounding generic biologics. Ann Neurol. 2013 Sep; 74(3):A7-8.
  6. Hauser SL, Chan JR, Oksenberg JR. Multiple sclerosis: Prospects and promise. Ann Neurol. 2013 Sep; 74(3):317-27.
  7. Isobe N, Damotte V, Lo Re V, Ban M, Pappas D, Guillot-Noel L, Rebeix I, Compston A, Mack T, Cozen W, Fontaine B, Hauser SL, Oksenberg JR, Sawcer S, Gourraud PA. Genetic burden in multiple sclerosis families. Genes Immun. 2013 Oct; 14(7):434-40.
  8. Schulze-Topphoff U, Casazza S, Varrin-Doyer M, Michel K, Sobel RA, Hauser SL, Oksenberg JR, Zamvil SS, Baranzini SE. Tob1 plays a critical role in the activation of encephalitogenic T cells in CNS autoimmunity. J Exp Med. 2013 Jul 1; 210(7):1301-9.
  9. Hauser SL, Johnston SC. Living in the time of sequestration. Ann Neurol. 2013 Jul; 74(1):A5-6.
  10. Isobe N, Gourraud PA, Harbo HF, Caillier SJ, Santaniello A, Khankhanian P, Maiers M, Spellman S, Cereb N, Yang S, Pando MJ, Piccio L, Cross AH, De Jager PL, Cree BA, Hauser SL, Oksenberg JR. Genetic risk variants in African Americans with multiple sclerosis. Neurology. 2013 Jul 16; 81(3):219-27.
  11. Nickles D, Chen HP, Li MM, Khankhanian P, Madireddy L, Caillier SJ, Santaniello A, Cree BA, Pelletier D, Hauser SL, Oksenberg JR, Baranzini SE. Blood RNA profiling in a large cohort of multiple sclerosis patients and healthy controls. Hum Mol Genet. 2013 Oct 15; 22(20):4194-205.
  12. Johnston SC, Hauser SL. The dangers of clinical conviction: an "M&M" of endovascular therapies for stroke. Ann Neurol. 2013 Jun; 73(6):A5-6.
  13. Josephson SA, Johnston SC, Hauser SL. The neurologic revolving door: time to pay attention to readmissions. Ann Neurol. 2013 May; 73(5):A5-6.
  14. Hauser SL, Josephson SA, Johnston SC. Multiple sclerosis: monotherapy rules. Ann Neurol. 2013 Mar; 73(3):A5-6.
  15. Ban M, Caillier S, Mero IL, Myhr KM, Celius EG, Aarseth J, Torkildsen , Harbo HF, Oksenberg J, Hauser SL, Sawcer S, Compston A. No evidence of association between mutant alleles of the CYP27B1 gene and multiple sclerosis. Ann Neurol. 2013 Mar; 73(3):430-2.
  16. Gourraud PA, Sdika M, Khankhanian P, Henry RG, Beheshtian A, Matthews PM, Hauser SL, Oksenberg JR, Pelletier D, Baranzini SE. A genome-wide association study of brain lesion distribution in multiple sclerosis. Brain. 2013 Apr; 136(Pt 4):1012-24.
  17. Johnston SC, Josephson SA, Hauser SL. Are relative value units hurting healthcare? Ann Neurol. 2013 Feb; 73(2):A5-6.
  18. Hauser SL, Johnston SC. DSM-V: psychodrama on the public stage. Ann Neurol. 2013 Jan; 73(1):A5-6.
  19. Hauser SL. Reply to Dr Sethi. Ann Neurol. 2013 Jan; 73(1):147.
  20. McElroy JP, Krupp LB, Johnson BA, McCauley JL, Qi Z, Caillier SJ, Gourraud PA, Yu J, Nathanson L, Belman AL, Hauser SL, Waubant E, Hedges DJ, Oksenberg JR. Copy number variation in pediatric multiple sclerosis. Mult Scler. 2013 Jul; 19(8):1014-21.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.