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William Ryan, M.D.


Dr. William R. Ryan is a head and neck surgeon at the UCSF Helen Diller Family Comprehensive Cancer Center. He is skilled in caring for patients with benign and malignant tumors with the appropriate application of endoscopic, minimally invasive and traditional surgical techniques. He regularly performs ultrasonography in clinic and in the operating room for his patients. He also has experience with sentinel lymph node biopsy and regional facial reconstruction. Ryan helps direct the Robotic Head and Neck Surgery program along with Dr. Steven J. Wang.

Ryan is committed to providing adequate information and being as accessible as possible to his patients.

Ryan is actively involved in teaching in the UCSF residency training program and School of Medicine. He is an assistant professor in the division of Head and Neck Oncologic and Endocrine Surgery in the department of Otolaryngology-Head and Neck Surgery. He also conducts clinical research on the outcomes of head and neck surgery and radiology.

Ryan earned his medical degree from Stanford University School of Medicine, where he also completed his residency in otolaryngology-head and neck surgery. Following his residency, he completed a fellowship in head and neck oncologic/endocrine/skull base surgery at UCSF. He joined the UCSF faculty in 2011.


Head and Neck Surgery Cancer Clinic
1825 Fourth St., Fourth Floor
San Francisco, CA 94158
Phone: (415) 885–7528
Fax: (415) 885–7711

Hours: Monday to Friday
8 a.m. – 5 p.m.

Salivary Gland Surgery Center at Mission Bay
1825 Fourth St., Fourth Floor
San Francisco, CA 94158
Phone: (415) 885–7528
Fax: (415) 885–7711

Hours: Monday to Friday,
8 a.m. – 5 p.m.

Thyroid and Parathyroid Surgery
1825 Fourth St., Fourth Floor
San Francisco, CA 94158
Phone: (415) 885-7528
Fax: (415) 885-7711

Hours: Monday to Friday, 8 a.m. – 5 p.m.

Conditions & Treatments

More about William Ryan


Stanford University School of Medicine 2005


Stanford University Medical Center 2010


UCSF, Advanced Head and Neck Oncologic Surgery 2011

Selected Research and Publications

  1. Heaton CM, Al-Shwaiheen F, Liu CS, Yom SS, Ryan WR. Prognostic significance of hyoid bone invasion in advanced base of tongue carcinoma treated by chemoradiation. Clin Otolaryngol. 2015 Jun; 40(3):260-5.
  2. Hemmat SM, Wang SJ, Uzelac A, Yom SS, Ryan WR. The Limitations of Routine Magnetic Resonance Imaging for Long-Term Post-Treatment Locoregional Surveillance of Salivary Carcinoma. ORL J Otorhinolaryngol Relat Spec. 2015 May 27; 77(3):132-140.
  3. Goepfert RP, Liu C, Ryan WR. Trans-oral robotic surgery and surgeon-performed trans-oral ultrasound for intraoperative location and excision of an isolated retropharyngeal lymph node metastasis of papillary thyroid carcinoma. Am J Otolaryngol. 2015 Apr 21.
  4. Al-Shwaiheen FA, Wang SJ, Uzelac A, Yom SS, Ryan WR. The advantages and drawbacks of routine magnetic resonance imaging for long-term post-treatment locoregional surveillance of oral cavity squamous cell carcinoma. Am J Otolaryngol. 2015 May-Jun; 36(3):415-23.
  5. Goepfert RP, Yom SS, Ryan WR, Cheung SW. Development of a chemoradiation therapy toxicity staging system for oropharyngeal carcinoma. Laryngoscope. 2015 Apr; 125(4):869-76.
  6. Prendes BL, Aubin-Pouliot A, Egbert N, Ryan WR. Elective lymphadenectomy during salvage for locally recurrent head and neck squamous cell carcinoma after radiation. Otolaryngol Head Neck Surg. 2014 Sep; 151(3):462-7.
  7. Ryan WR, Chang JL, Eisele DW. Surgeon-performed ultrasound and transfacial sialoendoscopy for complete parotid duct stenosis. Laryngoscope. 2014 Feb; 124(2):418-20.
  8. Ryan WR, Orloff LA. Intraoperative tumor localization with surgeon-performed ultrasound-guided needle dye injection. Laryngoscope. 2011 Aug; 121(8):1651-5.
  9. Ryan WR, Ramachandra T, Hwang PH. Correlations between symptoms, nasal endoscopy, and in-office computed tomography in post-surgical chronic rhinosinusitis patients. Laryngoscope. 2011 Mar; 121(3):674-8.
  10. Ryan WR, Hwang PH. Safety of a preservative-free acidified saline nasal spray: a randomized, double-blind, placebo-controlled, crossover clinical trial. Arch Otolaryngol Head Neck Surg. 2010 Nov; 136(11):1099-103.
  11. Ryan WR, Most SP. A prospective evaluation of the efficacy of topical adhesive pads for the reduction of facial rhytids. Arch Facial Plast Surg. 2009 Jul-Aug; 11(4):252-6.
  12. Ryan WR, Fee WE. Long-term great auricular nerve morbidity after sacrifice during parotidectomy. Laryngoscope. 2009 Jun; 119(6):1140-6.
  13. Ryan WR, Fee WE. Great auricular nerve morbidity after nerve sacrifice during parotidectomy. Arch Otolaryngol Head Neck Surg. 2006 Jun; 132(6):642-9.
  14. Ryan WR, Fee WE, Le QT, Pinto HA. Positron-emission tomography for surveillance of head and neck cancer. Laryngoscope. 2005 Apr; 115(4):645-50.
  15. Ryan WR, Allan RN, Yamamoto T, Keighley MR. Crohn's disease patients who quit smoking have a reduced risk of reoperation for recurrence. Am J Surg. 2004 Feb; 187(2):219-25.
  16. Ryan WR, Ley C, Allan RN, Keighley MR. Patients with Crohn's disease are unaware of the risks that smoking has on their disease. J Gastrointest Surg. 2003 Jul-Aug; 7(5):706-11.
  17. Quigley TM, Ryan WR, Morgan S. Patient satisfaction after carotid endarterectomy using a selective policy of local anesthesia. Am J Surg. 2000 May; 179(5):382-5.
  18. Fisher RL, Ryan WR, Dugdale TW, Zimmermann GA. Arthroscopic ankle fusion. Conn Med. 1997 Oct; 61(10):643-6.
  19. Ho JJ, Chung YS, Ryan W, Henslee JG, Kim YS. Evaluation of factors affecting the performance of enzymatic SPan-1 immunoassays for pancreatic cancer. J Immunol Methods. 1989 Dec 20; 125(1-2):97-104.
  20. Ho JJ, Chung YS, Fujimoto Y, Bi N, Ryan W, Yuan SZ, Byrd JC, Kim YS. Mucin-like antigens in a human pancreatic cancer cell line identified by murine monoclonal antibodies SPan-1 and YPan-1. Cancer Res. 1988 Jul 15; 48(14):3924-31.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.