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William L. Young, M.D.

Anesthesiologist

Dr. William L. Young is an anesthesiologist at UCSF Medical Center and director of the UCSF Center for Cerebrovascular Research, which studies neuroscience to improve the understanding of cerebrovascular disease. Young's research focuses on vascular malformations of the brain, such as arteriovenous malformations and aneurysms that can result in hemorrhagic stroke. He is the James P. Livingston Professor and vice chair of Anesthesia and Perioperative Care, and a professor of Neurological Surgery and Neurology.

Conditions & Treatments

More about William L. Young

Additional Languages

French
German

Education

Indiana University School of Medicine 1980

Residencies

New York Univeristy Medical Center 1983

Fellowships

Columbia University College of Physicians and Surgeons 1985

Selected Research and Publications

  1. Degos V, Vacas S, Han Z, van Rooijen N, Gressens P, Su H, Young WL, Maze M. Depletion of bone marrow-derived macrophages perturbs the innate immune response to surgery and reduces postoperative memory dysfunction. Anesthesiology. 2013 Mar; 118(3):527-36.
  2. Hasan DM, Chalouhi N, Jabbour P, Dumont AS, Kung DK, Magnotta VA, Young WL, Hashimoto T, Richard Winn H, Heistad D. Evidence that acetylsalicylic Acid attenuates inflammation in the walls of human cerebral aneurysms: preliminary results. J Am Heart Assoc. 2013; 2(1):e000019.
  3. Choi EJ, Walker EJ, Degos V, Jun K, Kuo R, Pile-Spellman J, Su H, Young WL. Endoglin Deficiency in Bone Marrow is Sufficient to Cause Cerebrovascular Dysplasia in the Adult Mouse After Vascular Endothelial Growth Factor Stimulation. Stroke. 2013 Mar; 44(3):795-8.
  4. Shen F, Kuo R, Milon-Camus M, Han Z, Jiang L, Young WL, Su H. Intravenous delivery of adeno-associated viral vector serotype 9 mediates effective gene expression in ischemic stroke lesion and brain angiogenic foci. Stroke. 2013 Jan; 44(1):252-4.
  5. Chen W, Guo Y, Walker EJ, Shen F, Jun K, Oh SP, Degos V, Lawton MT, Tihan T, Davalos D, Akassoglou K, Nelson J, Pile-Spellman J, Su H, Young WL. Reduced Mural Cell Coverage and Impaired Vessel Integrity After Angiogenic Stimulation in the Alk1-deficient Brain. Arterioscler Thromb Vasc Biol. 2013 Feb; 33(2):305-10.
  6. Zaroff JG, Leong J, Kim H, Young WL, Cullen SP, Rao VA, Sorel M, Quesenberry CP, Sidney S. Cardiovascular predictors of long-term outcomes after non-traumatic subarachnoid hemorrhage. Neurocrit Care. 2012 Dec; 17(3):374-81.
  7. Degos V, Gourraud PA, Tursis VT, Whelan R, Colonne C, Korinek AM, Clarençon F, Boch AL, Nouet A, Young WL, Apfel CC, Puybasset L. Elderly age as a prognostic marker of 1-year poor outcome for subarachnoid hemorrhage patients through its interaction with admission hydrocephalus. Anesthesiology. 2012 Dec; 117(6):1289-99.
  8. Rodríguez-Hernández A, Kim H, Pourmohamad T, Young WL, Lawton MT. Cerebellar arteriovenous malformations: anatomic subtypes, surgical results, and increased predictive accuracy of the supplementary grading system. Neurosurgery. 2012 Dec; 71(6):1111-24.
  9. Hasan D, Chalouhi N, Jabbour P, Dumont AS, Kung DK, Magnotta VA, Young WL, Hashimoto T, Winn HR, Heistad D. Early change in ferumoxytol-enhanced magnetic resonance imaging signal suggests unstable human cerebral aneurysm: a pilot study. Stroke. 2012 Dec; 43(12):3258-65.
  10. Khush KK, Pawlikowska L, Menza RL, Goldstein BA, Hayden V, Nguyen J, Kim H, Poon A, Sapru A, Matthay MA, Kwok PY, Young WL, Baxter-Lowe LA, Zaroff JG. Beta-adrenergic receptor polymorphisms and cardiac graft function in potential organ donors. Am J Transplant. 2012 Dec; 12(12):3377-86.
  11. Nishida T, Faughnan ME, Krings T, Chakinala M, Gossage JR, Young WL, Kim H, Pourmohamad T, Henderson KJ, Schrum SD, James M, Quinnine N, Bharatha A, Terbrugge KG, White RI. Brain arteriovenous malformations associated with hereditary hemorrhagic telangiectasia: Gene-phenotype correlations. Am J Med Genet A. 2012 Nov; 158A(11):2829-34.
  12. Englot DJ, Young WL, Han SJ, McCulloch CE, Chang EF, Lawton MT. Seizure predictors and control after microsurgical resection of supratentorial arteriovenous malformations in 440 patients. Neurosurgery. 2012 Sep; 71(3):572-80; discussion 580.
  13. Kim H, Pourmohamad T, Westbroek EM, McCulloch CE, Lawton MT, Young WL. Evaluating performance of the spetzler-martin supplemented model in selecting patients with brain arteriovenous malformation for surgery. Stroke. 2012 Sep; 43(9):2497-9.
  14. Lee CZ, Young WL. Anesthesia for endovascular neurosurgery and interventional neuroradiology. Anesthesiol Clin. 2012 Jun; 30(2):127-47.
  15. Kahle MP, Lee B, Pourmohamad T, Cunningham A, Su H, Kim H, Chen Y, McCulloch CE, Barbaro NM, Lawton MT, Young WL, Bix GJ. Perlecan domain V is upregulated in human brain arteriovenous malformation and could mediate the vascular endothelial growth factor effect in lesional tissue. Neuroreport. 2012 Jul 11; 23(10):627-30.
  16. Westbroek EM, Pawlikowska L, Lawton MT, McCulloch CE, Young WL, Kim H. Brain-derived neurotrophic factor Val66Met polymorphism predicts worse functional outcome after surgery in patients with unruptured brain arteriovenous malformation. Stroke. 2012 Aug; 43(8):2255-7.
  17. Hetts SW, Keenan K, Fullerton HJ, Young WL, English JD, Gupta N, Dowd CF, Higashida RT, Lawton MT, Halbach VV. Pediatric intracranial nongalenic pial arteriovenous fistulas: clinical features, angioarchitecture, and outcomes. AJNR Am J Neuroradiol. 2012 Oct; 33(9):1710-9.
  18. Mohr JP, Moskowitz AJ, Parides M, Stapf C, Young WL. Hull down on the horizon: A Randomized trial of Unruptured Brain Arteriovenous malformations (ARUBA) Trial. Stroke. 2012 Jul; 43(7):1744-5.
  19. Wang DD, Englot DJ, Garcia PA, Lawton MT, Young WL. Minocycline- and tetracycline-class antibiotics are protective against partial seizures in vivo. Epilepsy Behav. 2012 Jul; 24(3):314-8.
  20. Choi EJ, Walker EJ, Shen F, Oh SP, Arthur HM, Young WL, Su H. Minimal homozygous endothelial deletion of Eng with VEGF stimulation is sufficient to cause cerebrovascular dysplasia in the adult mouse. Cerebrovasc Dis. 2012; 33(6):540-7.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions by logging on to UCSF Profiles.