Bruce Cree, MD, PhD, MAS

Clinical Research Director at the UCSF Multiple Sclerosis Center
Neurologist

Dr. Bruce Cree is a neurologist with a special interest in multiple sclerosis. He treats patients with multiple sclerosis, neuromyelitis optics, transverse myelitis and other autoimmune and central nervous system disorders. Cree currently serves as the clinical research director at the UCSF Multiple Sclerosis Center.

Cree's research focuses on the role of genetics in multiple sclerosis, the immunology of neuromyelitis optica and developing new treatments for multiple sclerosis and neuromyelitis optica through clinical trials.

Cree received his medical degree and doctorate in biochemistry from UCSF. He completed his neurology residency at Columbia University followed by a neurology fellowship at UCSF. He also earned a masters in advanced studies in clinical research from the department of epidemiology and biostatistics at UCSF.

Cree is a member of the American Academy of Neurology, the American Neurological Association and the San Francisco Neurological Society. He is an associate professor of neurology at the UCSF School of Medicine.

Clinics

Multiple Sclerosis Center
1500 Owens St., Suite 320
San Francisco, CA 94158
Phone: (415) 353-2069
Fax: (415) 353-2633

Hours: Monday to Friday
8 a.m. – 5 p.m.

Academic Title

Associate Professor

More about Bruce Cree

Education

UCSF School of Medicine 1997

Residencies

Columbia Presbyterian Medical Center, Neurology 2001

Fellowships

UCSF Medical Center, Neurology 2003

Selected Research and Publications

  1. Cree BA, Bennett JL, Sheehan M, Cohen J, Hartung HP, Aktas O, Kim HJ, Paul F, Pittock S, Weinshenker B, Wingerchuk D, Fujihara K, Cutter G, Patra K, Flor A, Barron G, Madani S, Ratchford JN, Katz E. Placebo-controlled study in neuromyelitis optica-Ethical and design considerations. Mult Scler. 2016 06; 22(7):862-72.
  2. Cree BA. Placebo controlled trials in neuromyelitis optica are needed and ethical. Mult Scler Relat Disord. 2015 Nov; 4(6):536-45.
  3. Cree BA. Acute inflammatory myelopathies. Handb Clin Neurol. 2014; 122:613-67.
  4. Cree BA. Genetics of primary progressive multiple sclerosis. Handb Clin Neurol. 2014; 122:211-30.
  5. Cree BA. Multiple sclerosis genetics. Handb Clin Neurol. 2014; 122:193-209.
  6. Cree BA. Update on reproductive safety of current and emerging disease-modifying therapies for multiple sclerosis. Mult Scler. 2013 Jun; 19(7):835-43.
  7. Cree BA, Stuart WH, Tornatore CS, Jeffery DR, Pace AL, Cha CH. Efficacy of natalizumab therapy in patients of African descent with relapsing multiple sclerosis: analysis of AFFIRM and SENTINEL data. Arch Neurol. 2011 Apr; 68(4):464-8.
  8. Cree BA, Kornyeyeva E, Goodin DS. Pilot trial of low-dose naltrexone and quality of life in multiple sclerosis. Ann Neurol. 2010 Aug; 68(2):145-50.
  9. Cree BA, Rioux JD, McCauley JL, Gourraud PA, Goyette P, McElroy J, De Jager P, Santaniello A, Vyse TJ, Gregersen PK, Mirel D, Hafler DA, Haines JL, Pericak-Vance MA, Compston A, Sawcer SJ, Oksenberg JR, Hauser SL. A major histocompatibility Class I locus contributes to multiple sclerosis susceptibility independently from HLA-DRB1*15:01. PLoS One. 2010 Jun 25; 5(6):e11296.
  10. Cree BA, Reich DE, Khan O, De Jager PL, Nakashima I, Takahashi T, Bar-Or A, Tong C, Hauser SL, Oksenberg JR. Modification of Multiple Sclerosis Phenotypes by African Ancestry at HLA. Arch Neurol. 2009 Feb; 66(2):226-33.
  11. Cree B. Neuromyelitis optica: diagnosis, pathogenesis, and treatment. Curr Neurol Neurosci Rep. 2008 Sep; 8(5):427-33.
  12. Barcellos LF, Sawcer S, Ramsay PP, Baranzini SE, Thomson G, Briggs F, Cree BC, Begovich AB, Villoslada P, Montalban X, Uccelli A, Savettieri G, Lincoln RR, DeLoa C, Haines JL, Pericak-Vance MA, Compston A, Hauser SL, Oksenberg JR. Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis. Hum Mol Genet. 2006 Sep 15; 15(18):2813-24.
  13. Cree BC, Bernardini GL, Hays AP, Lowe G. A fatal case of coxsackievirus B4 meningoencephalitis. Arch Neurol. 2003 Jan; 60(1):107-12.
  14. Stüve O, Cree BC, von Büdingen HC, Yousef S, Bowen JD, Genain CP, Hauser SL, Steinman L, Zamvil SS. Approved and future pharmacotherapy for multiple sclerosis. Neurologist. 2002 Sep; 8(5):290-301.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.