Bryce Mendelsohn, MD, PhD

Medical geneticist

Dr. Bryce Mendelsohn is a clinical geneticist who provides evaluations and testing for pediatric and adult patients with suspected genetic conditions. He sees patients at the Medical Genetics and Genomics Clinic at Mission Bay, UCSF Medical Center at Parnassus and UCSF Benioff Children's Hospital Oakland.

Mendelsohn's areas of research include metabolic and mitochondrial diseases, which result from problems with cellular energy production that can eventually lead to complex dysfunction of multiple different organ systems. He is also interested in understanding how new genetic technologies impact health and costs in medicine, particularly for healthy people.

Mendelsohn received his medical degree from the Washington University School of Medicine in St. Louis, where he also completed a doctoral degree in molecular genetics and genomics. He completed post-doctoral work at the University of California, San Diego, and Gladstone Institutes in San Francisco. He also completed residencies in pediatrics and medical genetics at UCSF.

Mendelsohn is the author of "Precision Medicine: A Guide to Genomics in Clinical Practice," published by McGraw-Hill in 2016.


Biochemical Genetic Medicine Clinic
1825 Fourth St., Sixth Floor
San Francisco, CA 94158
Phone: (415) 476-9997
Fax: (415) 476-9976

Hours: Monday to Friday
8 a.m. – 5 p.m.

Lysosomal Disease Center
1825 Fourth St., Sixth Floor
San Francisco, CA 94158
Phone: (866) 476-9997
Fax: (415) 476-9976

Hours: Monday to Friday
9 a.m. – 5 p.m.

Medical Genetics and Genomics Clinic
1825 Fourth Street, Sixth Floor
San Francisco, CA 94158
Phone: (415) 476-2757
Fax: (415) 476-9305

Hours: Mondays, Tuesdays and Wednesdays

Preventive Genomics Clinic
2330 Post St., Suite 219
San Francisco, CA 94115
Phone: (415) 476-2757
Fax: (415) 476-9305
Email: Bryce.M

Academic Title

Assistant Professor

More about Bryce Mendelsohn


Washington University School of Medicine 2010


UCSF Medical Center 2016

Selected Research and Publications

  1. Hirabayashi KE, Moore AT, Mendelsohn BA, Taft RJ, Chawla A, Perry D, Henry D, Slavotinek A. Congenital sodium diarrhea and chorioretinal coloboma with optic disc coloboma in a patient with biallelic SPINT2 mutations, including p.(Tyr163Cys). Am J Med Genet A. 2018 Apr; 176(4):997-1000.
  2. Slavotinek A, Risolino M, Losa M, Cho MT, Monaghan KG, Schneidman-Duhovny D, Parisotto S, Herkert JC, Stegmann APA, Miller K, Shur N, Chui J, Muller E, DeBrosse S, Szot JO, Chapman G, Pachter NS, Winlaw DS, Mendelsohn BA, Dalton J, Sarafoglou K, Karachunski PI, Lewis JM, Pedro H, Dunwoodie SL, Selleri L, Shieh J. De novo, deleterious sequence variants that alter the transcriptional activity of the homeoprotein PBX1 are associated with intellectual disability and pleiotropic developmental defects. Hum Mol Genet. 2017 Dec 15; 26(24):4849-4860.
  3. Eppley S, Hopkin RJ, Mendelsohn B, Slavotinek AM. Clinical Report: Warsaw Breakage Syndrome with small radii and fibulae. Am J Med Genet A. 2017 Nov; 173(11):3075-3081.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.