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Clay Johnston, M.D.


Dr. Claiborne Johnston is a neurologist who treats patients with cerebral aneurysms, vascular malformations and stroke. Most of the care he provides occurs in the hospital, including the Neurological Intensive Care Unit, but he also provides follow-up care for patients with complex neurovascular disorders in the Neurovascular Disease and Stroke Center.

Johnston earned a medical degree at Harvard Medical School and completed a residency in neurology as well as a fellowship in neurovascular service at UCSF. He earned a doctorate in epidemiology at the University of California at Berkeley. At UCSF, Johnston is associate vice chancellor of research, director of the Clinical and Translational Science Institute, director of the hospital Stroke Service and a professor of neurology and epidemiology.


Neurovascular Disease and Stroke Center
400 Parnassus Ave., Eighth Floor
San Francisco, CA 94143
Phone: (415) 353-8897
Fax: (415) 353-8705

Hours: Monday to Friday
8:30 a.m. – 5 p.m.

Conditions & Treatments

More about Clay Johnston


Harvard Medical School 1992


UCSF, Neurology 1996


UCSF, Neurovascular 1998

Selected Research and Publications

  1. Poisson SN, Glidden D, Johnston SC, Fullerton HJ. Deaths from stroke in US young adults, 1989-2009. Neurology. 2014 Dec 2; 83(23):2110-5.
  2. Kahlon M, Yuan L, Gologorskaya O, Johnston SC. Crowdsourcing the CTSA Innovation Mission. Clin Transl Sci. 2014 Apr; 7(2):89-92.
  3. Grumbach K, Lucey CR, Johnston SC. Transforming from centers of learning to learning health systems: the challenge for academic health centers. JAMA. 2014 Mar 19; 311(11):1109-10.
  4. Wang Y, Johnston SC, Wang Y. Clopidogrel with aspirin in minor stroke or transient ischemic attack. N Engl J Med. 2013 Oct 3; 369(14):1376-7.
  5. Saposnik G, Johnston SC, Ovbiagele B. Response to letter regarding article, "Predicting clinical outcomes after thrombolysis using the iScore: results from the Virtual International Stroke Trials Archive". Stroke. 2013 Nov; 44(11):e155.
  6. Josephson SA, Johnston SC, Hauser SL. Blockbusters for cheap? The difficulties surrounding generic biologics. Ann Neurol. 2013 Sep; 74(3):A7-8.
  7. Douglas VC, Hessler CS, Dhaliwal G, Betjemann JP, Fukuda KA, Alameddine LR, Lucatorto R, Johnston SC, Josephson SA. The AWOL tool: derivation and validation of a delirium prediction rule. J Hosp Med. 2013 Sep; 8(9):493-9.
  8. Johnston SC, Easton JD, Farrant M, Barsan W, Battenhouse H, Conwit R, Dillon C, Elm J, Lindblad A, Morgenstern L, Poisson SN, Palesch Y. Platelet-oriented inhibition in new TIA and minor ischemic stroke (POINT) trial: rationale and design. Int J Stroke. 2013 Aug; 8(6):479-83.
  9. Saposnik G, Johnston SC, Raptis S, Ovbiagele B, Fisher M. Stroke journal: what is being published to advance the field? Stroke. 2013 Sep; 44(9):2644-9.
  10. Saposnik G, Reeves MJ, Johnston SC, Bath PM, Ovbiagele B. Predicting clinical outcomes after thrombolysis using the iScore: results from the Virtual International Stroke Trials Archive. Stroke. 2013 Oct; 44(10):2755-9.
  11. Hauser SL, Johnston SC. Living in the time of sequestration. Ann Neurol. 2013 Jul; 74(1):A5-6.
  12. Wang Y, Wang Y, Zhao X, Liu L, Wang D, Wang C, Wang C, Li H, Meng X, Cui L, Jia J, Dong Q, Xu A, Zeng J, Li Y, Wang Z, Xia H, Johnston SC. Clopidogrel with aspirin in acute minor stroke or transient ischemic attack. N Engl J Med. 2013 Jul 4; 369(1):11-9.
  13. Kiriakis J, Gaich N, Johnston SC, Kitterman D, Rosenblum D, Salberg L, Rifkind A. Observational study of contracts processing at 29 CTSA sites. Clin Transl Sci. 2013 Aug; 6(4):279-85.
  14. Kim AS, Johnston SC. Temporal and geographic trends in the global stroke epidemic. Stroke. 2013 Jun; 44(6 Suppl 1):S123-5.
  15. Johnston SC, Hauser SL. The dangers of clinical conviction: an "M&M" of endovascular therapies for stroke. Ann Neurol. 2013 Jun; 73(6):A5-6.
  16. Ovbiagele B, Goldstein LB, Higashida RT, Howard VJ, Johnston SC, Khavjou OA, Lackland DT, Lichtman JH, Mohl S, Sacco RL, Saver JL, Trogdon JG. Forecasting the future of stroke in the United States: a policy statement from the American Heart Association and American Stroke Association. Stroke. 2013 Aug; 44(8):2361-75.
  17. Hauser SL, Josephson SA, Johnston SC. Multiple sclerosis: monotherapy rules. Ann Neurol. 2013 Mar; 73(3):A5-6.
  18. Johnston SC, Josephson SA, Hauser SL. Are relative value units hurting healthcare? Ann Neurol. 2013 Feb; 73(2):A5-6.
  19. Nikneshan D, Raptis R, Pongmoragot J, Zhou L, Johnston SC, Saposnik G. Predicting clinical outcomes and response to thrombolysis in acute stroke patients with diabetes. Diabetes Care. 2013 Jul; 36(7):2041-7.
  20. Kim AS, Johnston SC. Is hypertension the key to reaching the healthy people 2000 goals by 2020? JAMA Intern Med. 2013 Jan 14; 173(1):51-3.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.