Signs & Symptoms Endocrinology

Cushing's Syndrome
Signs and Symptoms

Symptoms of Cushing's syndrome may include:

  • Change in body form, particularly weight gain in the face that is referred to as moon facies as well as fat deposition above the collar bone, called supraclavicular fat, and at the back of neck, called a buffalo hump.
  • Skin changes with easy bruising, purplish stretch marks, called stria, and red cheeks
  • Excess hair growth on face, neck, chest, abdomen and thighs
  • Overall weakness and fatigue
  • Loss of muscle bulk
  • Menstrual disorders in women
  • Decreased fertility and/or sex drive
  • Hypertension
  • Diabetes mellitus
  • Depression with wide mood swings

UCSF Health medical specialists have reviewed this information. It is for educational purposes only and is not intended to replace the advice of your doctor or other health care provider. We encourage you to discuss any questions or concerns you may have with your provider.