Growth Hormone Deficiency

Synthetic growth hormone, administered as daily injections, has proven to be an effective treatment of growth hormone deficiency.

In children, growth hormone replacement is critical for growth and development.

In adults, replacement therapy was controversial in the past but is now widely accepted.

Successful treatment with hormone replacement may be dependent on the patient's level of insulin-like growth factor 1 (IGF-1), which plays an important role in childhood growth. Its production is stimulated by growth hormone.

For patients with low levels of IGF-1, growth hormone levels can be adjusted to bring IGF-1 levels within a normal range. Benefits usually are noted in six to 18 months.

For patients with normal levels of IGF-1, there may be no benefit from growth hormone therapy.

Reviewed by health care specialists at UCSF Medical Center.

Related Information

UCSF Clinics & Centers

Neurology and Neurosurgery


Pituitary Disorders Center
400 Parnassus Ave., Eighth Floor
San Francisco, CA 94143
Phone: (866) 559-5543
or (415) 353-7500
Fax: (415) 353-2889
Appointment information

Endocrinology Clinic at Parnassus
400 Parnassus Ave., Suite A-550
San Francisco, CA 94143
Phone: (415) 353–2350
Fax: (415) 353–2337
Appointment information