Signs and Symptoms
Cancer in the liver may be primary or secondary, also called metastatic. Primary cancer arises within the liver and in its early stages exists only within the liver. At an early stage, primary liver cancer may cause no symptoms at all. More advanced disease may cause loss of appetite, weight loss, fever, fatigue and weakness.
Secondary liver cancer is the term for cancer that originates in another organ, such as the colon, stomach, pancreas and breast, and then spreads to the liver. As the cancer grows, pain may develop in the upper abdomen on the right side and may extend into the back and shoulder. With advanced disease, the signs of liver failure appear, which include abdominal swelling and a feeling of fullness or bloating and jaundice, a condition in which the skin and the whites of the eyes become yellow and the urine becomes dark.
UCSF Health medical specialists have reviewed this information. It is for educational purposes only and is not intended to replace the advice of your doctor or other health care provider. We encourage you to discuss any questions or concerns you may have with your provider.