Signs and Symptoms
People with Lynch syndrome may have:
- Colon cancer that occurs at a young age, especially before age 45
- A family history of colon cancer that occurs at a young age
- A family history of endometrial cancer
- A family history of other related cancers, including ovarian cancer, kidney cancer, stomach cancer, small bowel cancer, liver cancer or other cancers
Those with Lynch syndrome have a 70 percent chance of developing colon cancer by age 70. Colon cancer patients with Lynch syndrome have an estimated 40 percent risk of developing a second primary colon cancer within seven years of being diagnosed after the first tumor. Women with Lynch syndrome have a 40 percent to 60 percent estimated lifetime risk of developing endometrial cancer.
Lynch syndrome may also increase a person's risk for cancers of the stomach, ovary, urinary tract, hepatobiliary tract, brain, small intestine, skin and pancreas.
UCSF Health medical specialists have reviewed this information. It is for educational purposes only and is not intended to replace the advice of your doctor or other health care provider. We encourage you to discuss any questions or concerns you may have with your provider.