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Signs & Symptoms Hematology & Blood & Marrow Transplant (BMT)

Multiple Myeloma
Signs and Symptoms

Symptoms of multiple myeloma depend on how advanced the disease has become. In the earliest stages, a person may not have any symptoms.

When symptoms do occur, patients commonly experience:

  • Bone pain (often in the back or ribs)
  • Broken bones
  • Weakness
  • Fatigue
  • Weight loss
  • Repeated infections

When the disease is advanced, symptoms may include:

  • Nausea
  • Vomiting
  • Constipation
  • Problems with urination
  • Weakness or numbness in the legs

These are not sure signs of multiple myeloma, however — they can be caused by other medical problems. If you experience these symptoms, see a doctor as soon as possible. Only a health professional can determine what is causing a patient's symptoms.

UCSF Health medical specialists have reviewed this information. It is for educational purposes only and is not intended to replace the advice of your doctor or other health care provider. We encourage you to discuss any questions or concerns you may have with your provider.

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