Signs & Symptoms Heart & Vascular

Peripheral Artery Disease
Signs and Symptoms

While many patients with peripheral artery disease (PAD) have mild symptoms or no symptoms at all, about one in 10 experiences painful cramping or fatigue in the legs, hip, thigh or calf muscles after walking or climbing stairs, which is relieved by a short period of rest. This condition is called intermittent claudication.

Other symptoms include:

  • Change in the color of the legs
  • Changes in the toenails
  • Coldness in the lower leg or foot, especially compared to the other leg
  • Hair loss on the feet and legs
  • Leg numbness or weakness
  • Sores on the toes, feet or legs that won't heal

UCSF Health medical specialists have reviewed this information. It is for educational purposes only and is not intended to replace the advice of your doctor or other health care provider. We encourage you to discuss any questions or concerns you may have with your provider.

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