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Signs & Symptoms

Polycystic Kidney Disease, Autosomal Dominant
Signs and Symptoms

The most common warning signs of autosomal dominant PKD are pain in the side or back, and headaches. Some people also experience blood in the urine, frequent urinary tract infections, high blood pressure and kidney stones.

Most often, symptoms surface when patients are in their 30s or 40s, though occasionally they begin in childhood. Patients with a family history of PKD may be tested and diagnosed before experiencing any symptoms.

Serious complications of autosomal dominant PKD can include aneurysms (bulges in blood vessels in the brain), heart valve problems and diverticulosis (bulges in the wall of the colon). These complications are usually familial — in other words, your risk of aneurysm is higher if a family member with PKD has had an aneurysm.

UCSF Health medical specialists have reviewed this information. It is for educational purposes only and is not intended to replace the advice of your doctor or other health care provider. We encourage you to discuss any questions or concerns you may have with your provider.