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Signs & Symptoms Gastroenterology

Primary Biliary Cirrhosis
Signs and Symptoms

The initial signs and symptoms of PBC may be subtle, detectable only with blood testing. As the disease progresses over time, usually years, patients may suffer from itching and fatigue.

At an advanced stage, jaundice — a condition that gives a yellow tint to the skin and eyes — develops along with other signs of liver failure. These may include memory problems, fluid retention and internal bleeding.

UCSF Health medical specialists have reviewed this information. It is for educational purposes only and is not intended to replace the advice of your doctor or other health care provider. We encourage you to discuss any questions or concerns you may have with your provider.