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David Larson, M.D.

Radiosurgery specialist

Dr. David A. Larson is an internationally recognized authority on brain and body radiosurgery and intensity modified radiotherapy for treatment of central nervous system tumors. He lectures extensively and has authored more than 200 scientific papers, reviews and book chapters.

Larson is past president of the International Stereotactic Radiosurgery Society and American Society for Therapeutic Radiology and Oncology. He has organized many national and international conferences and serves on the editorial board of numerous medical journals. He holds a Ph.D. in high-energy physics from the University of Chicago and an M.D. from the University of Miami. After completing a medical internship at UCSF and a radiation oncology residency at Harvard, he joined the UCSF Medical Center faculty, where he serves as professor in the departments of Radiation Oncology and Neurological Surgery.


Radiation Oncology at Mount Zion
1600 Divisadero St., Basement Level
San Francisco, CA 94143-1708
Main Phone: (415) 353-7175
New Patient Appointments: (415) 353-9807
Fax: (415) 353-9884

Hours: Monday to Friday
7 a.m. – 6 p.m.

Radiation Oncology at Parnassus
505 Parnassus Ave, Room L-75
San Francisco, CA 94143-0226
Main Phone: (415) 353-7175
New Patient Appointments: (415) 353-8335
Fax: (415) 353-7281

Hours: Monday to Friday
8 a.m. – 4:30 p.m.

Conditions & Treatments

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University of Miami 1981


Harvard University, Radiation Oncology 1985

Selected Research and Publications

  1. Ma L, Sahgal A, Larson DA. Letter: Volumetric Arc Therapy (RapidArc) vs Gamma Knife Radiosurgery for Multiple Brain Metastases. Neurosurgery. 2015 Mar; 76(3):E353.
  2. Sahgal A, Larson D, Knisely J. Stereotactic radiosurgery alone for brain metastases. Lancet Oncol. 2015 Mar; 16(3):249-50.
  3. Barani IJ, Larson DA. Radiation therapy of glioblastoma. Cancer Treat Res. 2015; 163:49-73.
  4. Barani IJ, Raleigh DR, Larson D. The management of central neurocytoma: radiotherapy. Neurosurg Clin N Am. 2015 Jan; 26(1):45-56.
  5. Ma L, Mason E, Sneed PK, McDermott M, Polishchuk A, Larson DA, Sahgal A. Clinical realization of sector beam intensity modulation for gamma knife radiosurgery: a pilot treatment planning study. Int J Radiat Oncol Biol Phys. 2015 Mar 1; 91(3):661-8.
  6. Lee CS, Larson DB. Beginner's Guide to Practice Quality Improvement Using the Model for Improvement. J Am Coll Radiol. 2014 Dec; 11(12 Pt A):1131-6.
  7. Torrens M, Chung C, Chung HT, Hanssens P, Jaffray D, Kemeny A, Larson D, Levivier M, Lindquist C, Lippitz B, Novotny J, Paddick I, Prasad D, Yu CP. Standardization of terminology in stereotactic radiosurgery: Report from the Standardization Committee of the International Leksell Gamma Knife Society: special topic. J Neurosurg. 2014 Dec; 121 Suppl:2-15.
  8. Abla AA, Rutledge WC, Seymour ZA, Guo D, Kim H, Gupta N, Sneed PK, Barani IJ, Larson D, McDermott MW, Lawton MT. A treatment paradigm for high-grade brain arteriovenous malformations: volume-staged radiosurgical downgrading followed by microsurgical resection. J Neurosurg. 2015 Feb; 122(2):419-32.
  9. Ma L, Sahgal A, Larson DA, Pinnaduwage D, Fogh S, Barani I, Nakamura J, McDermott M, Sneed P. Impact of millimeter-level margins on peripheral normal brain sparing for gamma knife radiosurgery. Int J Radiat Oncol Biol Phys. 2014 May 1; 89(1):206-13.
  10. Hallemeier CL, You YN, Larson DW, Dozois EJ, Nelson H, Klein KA, Miller RC, Haddock MG. Multimodality therapy including salvage surgical resection and intraoperative radiotherapy for patients with squamous-cell carcinoma of the anus with residual or recurrent disease after primary chemoradiotherapy. Dis Colon Rectum. 2014 Apr; 57(4):442-8.
  11. Larson DB, Duncan JR, Nagy PG, Kruskal JB. Guide to effective quality improvement reporting in radiology. Radiology. 2014 May; 271(2):561-73.
  12. Maa J, Waterford S, Jahan T, Larson DA, Chou D. A novel use of foley catheters to prevent injury to the pelvic viscera during stereotactic radiosurgery for undifferentiated pleomorphic sarcoma of the sacrum. Perm J. 2014; 18(3):e146-9.
  13. Larson DA. Introduction: Top 25 cited articles on Gamma Knife surgery for vestibular schwannoma in journals of the American Association of Neurological Surgeons. J Neurosurg. 2013 Dec; 119 Suppl:1-2.
  14. Merchea A, Abdelsattar ZM, Taner T, Dean PG, Colibaseanu DT, Larson DW, Dozois EJ. Outcomes of colorectal cancer arising in solid organ transplant recipients. J Gastrointest Surg. 2014 Mar; 18(3):599-604.
  15. Sahgal A, Whyne CM, Ma L, Larson DA, Fehlings MG. Vertebral compression fracture after stereotactic body radiotherapy for spinal metastases. Lancet Oncol. 2013 Jul; 14(8):e310-20.
  16. Larson DB, Wang LL, Podberesky DJ, Goske MJ. System for verifiable CT radiation dose optimization based on image quality. part I. Optimization model. Radiology. 2013 Oct; 269(1):167-76.
  17. Larson DB, Malarik RJ, Hall SM, Podberesky DJ. System for verifiable CT radiation dose optimization based on image quality. part II. process control system. Radiology. 2013 Oct; 269(1):177-85.
  18. Seung SK, Larson DA, Galvin JM, Mehta MP, Potters L, Schultz CJ, Yajnik SV, Hartford AC, Rosenthal SA. American College of Radiology (ACR) and American Society for Radiation Oncology (ASTRO) Practice Guideline for the Performance of Stereotactic Radiosurgery (SRS). Am J Clin Oncol. 2013 Jun; 36(3):310-5.
  19. Abdelsattar ZM, Mathis KL, Colibaseanu DT, Merchea A, Bower TC, Larson DW, Dozois EJ. Surgery for locally advanced recurrent colorectal cancer involving the aortoiliac axis: can we achieve R0 resection and long-term survival? Dis Colon Rectum. 2013 Jun; 56(6):711-6.
  20. Berdahl CT, Vermeulen MJ, Larson DB, Schull MJ. Emergency department computed tomography utilization in the United States and Canada. Ann Emerg Med. 2013 Nov; 62(5):486-494.e3.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.