Farid Chehab, PhD

Laboratory medicine specialist

Academic Title

Professor

Selected Research and Publications

  1. Stieglitz E, Mazor T, Olshen AB, Geng H, Gelston LC, Akutagawa J, Lipka DB, Plass C, Flotho C, Chehab FF, Braun BS, Costello JF, Loh ML. Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia. Nat Commun. 2017 Dec 19; 8(1):2127.
  2. Jai SR, Farah RH, Hamdaoui B, Boufettal R, Chehab F. Pleomorphous leiomyosarcoma of the mesocolon: a case report. Pan Afr Med J. 2015; 22:322.
  3. Lasater EA, Massi ES, Stecula A, Politi J, Tan SK, Smith CC, Gunthorpe M, Holmes JP, Chehab F, Sali A, Shah NP. Novel TKI-resistant BCR-ABL1 gatekeeper residue mutations retain in vitro sensitivity to axitinib. Leukemia. 2016 06; 30(6):1405-9.
  4. Boufettal R, Fahmi Y, Jai SR, Chehab F. Videocapsule retention: role of surgical treatment (a case report). Pan Afr Med J. 2015; 22:64.
  5. Eljai RS, Boufettal R, Farah RH, Chehab F. [Pancreatic hydatid cyst: a case about]. Pan Afr Med J. 2015; 21:273.
  6. Boufettal R, Elbakouri A, Jai SR, Chehab F. [Pancreatic heterotopia as an unusual cause of upper gastrointestinal bleeding]. Presse Med. 2015 Mar; 44(3):368-9.
  7. Zouheir Habbal M, Bou-Assi T, Zhu J, Owen R, Chehab FF. First report of a deletion encompassing an entire exon in the homogentisate 1,2-dioxygenase gene causing alkaptonuria. PLoS One. 2014; 9(9):e106948.
  8. Chehab FF. 20 years of leptin: leptin and reproduction: past milestones, present undertakings, and future endeavors. J Endocrinol. 2014 Oct; 223(1):T37-48.
  9. Zhu J, Jiang X, Chehab FF. FoxO4 interacts with the sterol regulatory factor SREBP2 and the hypoxia inducible factor HIF2a at the CYP51 promoter. J Lipid Res. 2014 Mar; 55(3):431-42.
  10. Van Ziffle J, Yang W, Chehab FF. Homozygous deletion of six olfactory receptor genes in a subset of individuals with Beta-thalassemia. PLoS One. 2011 Feb 24; 6(2):e17327.
  11. Zhu J, Mounzih K, Chehab EF, Mitro N, Saez E, Chehab FF. Effects of FoxO4 overexpression on cholesterol biosynthesis, triacylglycerol accumulation, and glucose uptake. J Lipid Res. 2010 Jun; 51(6):1312-24.
  12. Wang B, Zhu J, Mounzih K, Chehab EF, Ke Y, Chehab FF. Overexpression of the transcription factor Foxo4 is associated with rapid glucose clearance. Mol Cell Endocrinol. 2009 Aug 13; 307(1-2):217-23.
  13. Chehab FF. Obesity and lipodystrophy--where do the circles intersect? Endocrinology. 2008 Mar; 149(3):925-34.
  14. Wang B, Chehab FF. Deletion of the serotonin 2c receptor from transgenic mice overexpressing leptin does not affect their lipodystrophy but exacerbates their diet-induced obesity. Biochem Biophys Res Commun. 2006 Dec 15; 351(2):418-23.
  15. Han XD, Powell BR, Phalin JL, Chehab FF. Mosaicism for a full mutation, premutation, and deletion of the CGG repeats results in 22% FMRP and elevated FMR1 mRNA levels in a high-functioning fragile X male. Am J Med Genet A. 2006 Jul 01; 140(13):1463-71.
  16. Chehab FF, Qiu J, Ogus S. The use of animal models to dissect the biology of leptin. Recent Prog Horm Res. 2004; 59:245-66.
  17. Ke Y, Qiu J, Ogus S, Shen WJ, Kraemer FB, Chehab FF. Overexpression of leptin in transgenic mice leads to decreased basal lipolysis, PKA activity, and perilipin levels. Biochem Biophys Res Commun. 2003 Dec 26; 312(4):1165-70.
  18. Ogus S, Ke Y, Qiu J, Wang B, Chehab FF. Hyperleptinemia precipitates diet-induced obesity in transgenic mice overexpressing leptin. Endocrinology. 2003 Jul; 144(7):2865-9.
  19. Chehab FF, Qiu J, Mounzih K, Ewart-Toland A, Ogus S. Leptin and reproduction. Nutr Rev. 2002 Oct; 60(10 Pt 2):S39-46; discussion S68-84, 85-7.
  20. Qiu J, Ogus S, Mounzih K, Ewart-Toland A, Chehab FF. Leptin-deficient mice backcrossed to the BALB/cJ genetic background have reduced adiposity, enhanced fertility, normal body temperature, and severe diabetes. Endocrinology. 2001 Aug; 142(8):3421-5.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.