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Kari Connolly, M.D.

Autoimmune dermatologist

Dr. Kari Connolly is a dermatologist and rheumatologist whose overall interest is in autoimmune skin diseases and the mechanisms by which tissue damage occurs. Connolly is involved with a variety of research studies involving scleroderma, lupus erythematosus, dermatomyositis and blistering diseases. Her laboratory processes several hundred skin specimens a year. She also participates in clinical trials looking at treatment in autoimmune diseases.

Connolly earned a medical degree at Albany Medical College in New York in 1984 with honors. She completed a three-year internal medicine residency at UCLA and became board certified in 1987. Her interest in autoimmune diseases brought Connolly to UCSF Medical Center where she did a combined fellowship in rheumatology and residency in dermatology. She completed her postdoctoral studies in the laboratory of Dr. David Wofsy in murine models of systemic lupus erythematosus. She joined the faculty with a joint appointment in Dermatology and Medicine (Rheumatology) in 1991. Connolly has received honors and awards in the areas of research, teaching and patient care.

To make an appointment with Connolly, patients need a referral from a dermatologist or rheumatologist.


Dermatology Clinic
1701 Divisadero St., Third and Fourth Floors
San Francisco, CA 94115
Phone: (415) 353–7800
Fax: (415) 353–7870

Hours: Monday to Friday, 8 a.m. – 5 p.m.

Scleroderma Clinic
400 Parnassus Ave., Floor B1
San Francisco, CA 94143
Phone: (415) 353–2497
Fax: (415) 353–2530

Hours: Monday to Friday; 8 a.m. to 4 p.m.

Conditions & Treatments

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Albany Medical College 1984


UCLA Medical Center, Internal Medicine 1987


UCSF Medical Center, Rheumatology 1990
UCSF Medical Center, Dermatology 1991

Selected Research and Publications

  1. Kaiser R, Connolly K, Linker C, Maldonado J, Fye K. Stem cell transplant for myelodysplastic syndrome-associated histiocytoid Sweet's syndrome in a patient with arthritis and myalgias. Arthritis Rheum. 2008 Dec 15; 59(12):1832-4.
  2. Kadlecek TA, van Oers NS, Lefrancois L, Olson S, Finlay D, Chu DH, Connolly K, Killeen N, Weiss A. Differential requirements for ZAP-70 in TCR signaling and T cell development. J Immunol. 1998 Nov 1; 161(9):4688-94.
  3. van Oers NS, Lowin-Kropf B, Finlay D, Connolly K, Weiss A. alpha beta T cell development is abolished in mice lacking both Lck and Fyn protein tyrosine kinases. Immunity. 1996 Nov; 5(5):429-36.
  4. Connolly K, Roubinian JR, Wofsy D. Development of murine lupus in CD4-depleted NZB/NZW mice. Sustained inhibition of residual CD4+ T cells is required to suppress autoimmunity. J Immunol. 1992 Nov 1; 149(9):3083-8.

Publications are derived from MEDLINE/PubMed and provided by UCSF Profiles, a service of the Clinical & Translational Science Institute (CTSI) at UCSF. Researchers can make corrections and additions to their publications by logging on to UCSF Profiles.